KEGG   Homo sapiens (human): 55270
Entry
55270             CDS       T01001                                 
Symbol
NUDT15, MTH2, NUDT15D
Name
(RefSeq) nudix hydrolase 15
  KO
K03574  8-oxo-dGTP diphosphatase [EC:3.6.1.55]
Organism
hsa  Homo sapiens (human)
Disease
H00964  Poor metabolism of thiopurines
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    55270 (NUDT15)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.55  8-oxo-dGTP diphosphatase
     55270 (NUDT15)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    55270 (NUDT15)
 Prokaryotic type
    55270 (NUDT15)
SSDB
Motif
Pfam: NUDIX Brr6_like_C_C NUDIX_4
Other DBs
NCBI-GeneID: 55270
NCBI-ProteinID: NP_060753
OMIM: 615792
HGNC: 23063
Ensembl: ENSG00000136159
UniProt: Q9NV35
Structure
Position
13:48037726..48052755
AA seq 164 aa
MTASAQPRGRRPGVGVGVVVTSCKHPRCVLLGKRKGSVGAGSFQLPGGHLEFGETWEECA
QRETWEEAALHLKNVHFASVVNSFIEKENYHYVTILMKGEVDVTHDSEPKNVEPEKNESW
EWVPWEELPPLDQLFWGLRCLKEQGYDPFKEDLNHLVGYKGNHL
NT seq 495 nt   +upstreamnt  +downstreamnt
atgacggccagcgcacagccgcgcgggcggcggccaggagtcggagtcggagtcgtggtg
accagctgcaagcatccgcgttgcgtcctcctggggaagaggaaaggctcggttggagct
ggcagtttccaactccctggaggtcatctggagttcggtgaaacctgggaagaatgtgct
caaagggaaacctgggaagaagcagctcttcacctgaaaaatgttcactttgcctcagtt
gtgaattctttcattgagaaggagaattaccattatgttactatattaatgaaaggagaa
gtggatgtgactcatgattcagaaccaaagaatgtagagcctgaaaaaaatgaaagttgg
gagtgggttccttgggaagaactacctcccctggaccagcttttctggggactgcgttgt
ttaaaagaacaaggctatgatccatttaaagaagatctgaaccatctggtgggatacaaa
ggaaatcatctctag

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