KEGG   Homo sapiens (human): 5547
Entry
5547              CDS       T01001                                 
Symbol
PRCP, HUMPCP, PCP
Name
(RefSeq) prolylcarboxypeptidase
  KO
K01285  lysosomal Pro-X carboxypeptidase [EC:3.4.16.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04614  Renin-angiotensin system
hsa04974  Protein digestion and absorption
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04614 Renin-angiotensin system
    5547 (PRCP)
  09154 Digestive system
   04974 Protein digestion and absorption
    5547 (PRCP)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    5547 (PRCP)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.16  Serine-type carboxypeptidases
    3.4.16.2  lysosomal Pro-Xaa carboxypeptidase
     5547 (PRCP)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S28
   5547 (PRCP)
SSDB
Motif
Pfam: Peptidase_S28 Hydrolase_4 Peptidase_S37 DUF2920 Abhydrolase_6 Peptidase_S9 Abhydrolase_1
Other DBs
NCBI-GeneID: 5547
NCBI-ProteinID: NP_005031
OMIM: 176785
HGNC: 9344
Ensembl: ENSG00000137509
UniProt: P42785
Structure
Position
11:complement(82822936..82901644)
AA seq 496 aa
MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHF
GFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFA
EHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSY
GGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRS
WDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQP
LPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWS
YQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHT
NIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRH
MKNWIRDFYDSAGKQH
NT seq 1491 nt   +upstreamnt  +downstreamnt
atgggccgccgagccctcctgctcctgcttctgtcttttctggcgccctgggccaccata
gccctccggccggccttaagggccctcggcagcctacacttgccaaccaaccccacatcc
ctcccggctgtagccaagaactattcggttctctacttccaacagaaggttgatcatttt
ggatttaatactgtgaaaacttttaatcagcggtacctagtagctgataaatactggaag
aaaaatggtggatcaatacttttctacactggtaatgaaggggacattatctggttttgt
aataacacggggttcatgtgggatgtggctgaggaactgaaagctatgttggtgtttgct
gaacatcgatactatggagagtctctcccctttggtgacaactcattcaaggattccaga
cacttgaatttcctgacatcagaacaagctctggctgattttgcagagttaatcaaacac
ttgaaaagaacaatcccaggagctgaaaatcaacctgtcattgccataggaggctcctat
ggtggcatgcttgccgcctggtttaggatgaaatatcctcatatggtagttggagctctt
gcagcttctgcccctatctggcagtttgaggatttagtaccttgtggtgtatttatgaag
atcgtaactacagattttaggaaaagcggtccacattgttcagagagcatccacaggtcc
tgggatgccattaatcgactctcaaatactggcagtggtttgcagtggcttactggagcc
cttcacttatgcagcccattaacttctcaggacatccaacatttgaaagactggatctct
gaaacctgggtgaatctggcaatggtggactatccttatgcctctaactttttacagcct
ttgcctgcttggcctatcaaggtagtgtgccagtatttgaaaaatcccaatgtatctgat
tcactgctgctgcagaatattttccaagctctgaatgtatattacaattattcgggccag
gtgaaatgcctgaatatttcagagacagcaactagcagtctgggaacactgggttggagc
tatcaggcctgcacagaagtagtcatgcccttttgtactaatggtgtcgatgacatgttt
gaacctcactcatggaacttaaaggaactttctgatgactgttttcaacagtggggtgtg
agaccaaggccctcctggatcactactatgtatggaggcaaaaacattagttcacacaca
aacattgttttcagcaatggtgaactagacccctggtcaggaggtggagtaactaaggat
atcacagacactctggttgcagtcaccatctcagagggggcccaccacttagatctccgc
accaagaatgccttggatcctatgtctgtgctgttagcccgctccttggaagttagacat
atgaagaattggatcagagatttctatgacagtgcgggaaagcagcactga

  All links  
Disease (1)   
   OMIM (1)   
Gene (19)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (39)   
   RefSeq(nuc) (5)   
   GenBank (17)   
   EMBL (17)   
3D Structure (1)   
   PDB (1)   
Protein domain (7)   
   Pfam (7)   
All databases (74)   

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