KEGG   Homo sapiens (human): 55818
Entry
55818             CDS       T01001                                 
Symbol
KDM3A, JHDM2A, JHMD2A, JMJD1, JMJD1A, TSGA
Name
(RefSeq) lysine demethylase 3A
  KO
K15601  [histone H3]-dimethyl-L-lysine9 demethylase [EC:1.14.11.65]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04714  Thermogenesis
Network
nt06529  Thermogenesis
  Element
N01688  ADRB3-UCP1 signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09159 Environmental adaptation
   04714 Thermogenesis
    55818 (KDM3A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    55818 (KDM3A)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.65  [histone H3]-dimethyl-L-lysine9 demethylase
     55818 (KDM3A)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   Histone demethylases
    55818 (KDM3A)
SSDB
Motif
Pfam: DUF7030 PWWP_KDM3B JmjC Tudor_KDM3B zf-UDP Cupin_2 C1_2
Other DBs
NCBI-GeneID: 55818
NCBI-ProteinID: NP_001140160
OMIM: 611512
HGNC: 20815
Ensembl: ENSG00000115548
UniProt: Q9Y4C1
Position
2:86437044..86492716
AA seq 1321 aa
MVLTLGESWPVLVGRRFLSLSAADGSDGSHDSWDVERVAEWPWLSGTIRAVSHTDVTKKD
LKVCVEFDGESWRKRRWIEVYSLLRRAFLVEHNLVLAERKSPEISERIVQWPAITYKPLL
DKAGLGSITSVRFLGDQQRVFLSKDLLKPIQDVNSLRLSLTDNQIVSKEFQALIVKHLDE
SHLLKGDKNLVGSEVKIYSLDPSTQWFSATVINGNPASKTLQVNCEEIPALKIVDPSLIH
VEVVHDNLVTCGNSARIGAVKRKSSENNGTLVSKQAKSCSEASPSMCPVQSVPTTVFKEI
LLGCTAATPPSKDPRQQSTPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKSEALRTK
PDVCKAGLLSKSSQIGTGDLKILTEPKGSCTQPKTNTDQENRLESVPQALTGLPKECLPT
KASSKAELEIANPPELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSALACR
SQNLKESSVKVDNESCCSRSNNKIQNAPSRKSVLTDPAKLKKLQQSGEAFVQDDSCVNIV
AQLPKCRECRLDSLRKDKEQQKDSPVFCRFFHFRRLQFNKHGVLRVEGFLTPNKYDNEAI
GLWLPLTKNVVGIDLDTAKYILANIGDHFCQMVISEKEAMSTIEPHRQVAWKRAVKGVRE
MCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKNCQQGAAYKTFSWLKCVKSQIHEPENL
MPTQIIPGKALYDVGDIVHSVRAKWGIKANCPCSNRQFKLFSKPASKEDLKQTSLAGEKP
TLGAVLQQNPSVLEPAAVGGEAASKPAGSMKPACPASTSPLNWLADLTSGNVNKENKEKQ
PTMPILKNEIKCLPPLPPLSKSSTVLHTFNSTILTPVSNNNSGFLRNLLNSSTGKTENGL
KNTPKILDDIFASLVQNKTTSDLSKRPQGLTIKPSILGFDTPHYWLCDNRLLCLQDPNNK
SNWNVFRECWKQGQPVMVSGVHHKLNSELWKPESFRKEFGEQEVDLVNCRTNEIITGATV
GDFWDGFEDVPNRLKNEKEPMVLKLKDWPPGEDFRDMMPSRFDDLMANIPLPEYTRRDGK
LNLASRLPNYFVRPDLGPKMYNAYGLITPEDRKYGTTNLHLDVSDAANVMVYVGIPKGQC
EQEEEVLKTIQDGDSDELTIKRFIEGKEKPGALWHIYAAKDTEKIREFLKKVSEEQGQEN
PADHDPIHDQSWYLDRSLRKRLHQEYGVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKV
AEDFVSPEHVKHCFWLTQEFRYLSQTHTNHEDKLQVKNVIYHAVKDAVAMLKASESSFGK
P
NT seq 3966 nt   +upstreamnt  +downstreamnt
atggtgctcacgctcggagaaagttggccggtattggtggggaggaggtttctcagtctg
tccgcagccgacggcagcgatggcagccacgacagctgggacgtggagcgcgtcgccgag
tggccctggctctccgggaccattcgagctgtttcccacaccgacgttaccaagaaggat
ctgaaggtgtgtgtggaatttgatggggaatcttggaggaaaagaagatggatagaagtc
tacagccttctaaggagagcatttttagtagaacataatttggttttagctgaacgaaag
tcacctgaaatttctgaacgaattgtacagtggcctgcaataacgtacaaacctctgttg
gacaaagctggtttgggatccataacttctgttcgctttctgggagatcaacaaagagta
tttctttctaaagaccttttgaagcctatacaggatgtaaacagtcttcgactttctctt
acggataatcagattgtcagtaaagaatttcaagctttgattgtgaagcatttagatgaa
agccatcttttaaaaggtgacaaaaacttagttggttcagaagtaaaaatttatagcttg
gacccatctactcagtggttttcagcaaccgttataaatggaaacccagcatcaaaaact
cttcaagtcaactgtgaggagattccagcactgaaaattgttgatccgtcactgattcat
gttgaagttgtacacgataaccttgtgacatgtggtaattctgcaagaattggagctgta
aaacgcaagtcttctgagaataatggaaccctggtttccaaacaagcaaaatcttgctct
gaggcctctcccagtatgtgtcctgtgcagtctgtacctacaacagtttttaaggagata
ctgcttggctgtactgcggcaactccacctagtaaggacccaagacagcaaagtactccc
caggctgccaactctccacctaaccttggagcaaaaattcctcaaggatgtcataaacaa
agtttaccagaggaaatttcttcctgtctaaatacaaagtctgaagctctgagaacaaaa
ccagatgtctgcaaagcagggttgctctcaaagtcctctcagattggaactggagacttg
aaaattctgactgagccaaaaggcagctgtactcagcctaagacaaacactgatcaggaa
aacagattggagtctgttccacaagcattgactggccttcctaaggagtgcttacctaca
aaggcttcttctaaggcagaattggaaattgccaatcctcctgaactgcagaagcaccta
gaacatgcaccttccccatcggatgtttcaaatgcaccagaagtgaaagcaggtgtcaat
agtgatagccctaataactgttcaggaaaaaaggtagaaccttcagctttagcttgccga
tcacagaatttaaaggaatcttcagtaaaagtagataatgaaagctgttgttcaagaagc
aacaataaaatccagaatgccccatccaggaagtcggttttgacagacccagctaaactc
aaaaagctgcaacagagtggcgaggccttcgtacaggatgattcttgtgtgaacatcgtg
gcacagttgcctaaatgccgagagtgtcgcttggacagtctccgcaaggataaggagcaa
cagaaggactcacctgtgttttgccgcttctttcacttcaggaggttacaattcaacaaa
catggtgtgttgcgggtagaaggcttcttaacaccaaacaagtatgacaatgaagcaatt
ggcttgtggttacctttaaccaaaaacgttgtggggattgatttggacacagcaaagtac
atcttggccaacattggagaccacttctgtcaaatggtgatttctgaaaaggaagctatg
tcaactattgagccacacagacaggttgcttggaagcgagctgtcaaaggtgttcgagaa
atgtgtgatgtgtgcgacaccaccatcttcaacctgcactgggtgtgtcctcggtgtggg
tttggagtatgtgtggactgctaccggatgaagagaaagaattgccaacagggtgctgct
tacaagactttctcttggctaaaatgtgtgaagagtcagatacatgaaccagagaactta
atgcccacacagatcattcctggaaaagcactctatgatgttggagacattgttcattct
gtaagagcgaaatggggaataaaggcaaactgcccttgttcaaacaggcaattcaaactc
ttttcaaagccagcctcaaaggaagacctaaaacagacttctttagctggagaaaaaccg
actcttggtgcagtgctccagcagaatccctcagtgttggagccagcagctgtgggtggg
gaagcagcctccaagccagccggcagcatgaagcctgcctgtccagccagcacatctcct
ctaaactggctggccgacctaaccagcgggaatgtcaacaaggaaaacaaggaaaaacaa
ccaacaatgccaattttaaagaatgaaatcaaatgccttccacccctcccacctttaagc
aaatccagcacagtcctccatacgtttaacagcacaattttgacacccgtaagcaacaac
aattctggtttcctccggaatctcttgaattcttctacaggaaagacagaaaatggactc
aagaatacaccaaaaatccttgatgacatctttgcctctttggtgcaaaataagacgact
tctgatttatctaagaggcctcaaggactaaccatcaagcccagcattctgggctttgac
actcctcactattggctttgtgataatcgcttgctgtgcttgcaagaccccaacaataag
agcaactggaatgtgtttagggagtgctggaaacaagggcagccagtgatggtgtctgga
gtgcatcataaattgaactctgaactttggaaacctgaatccttcaggaaagagtttggt
gagcaggaagtagacctagttaattgtaggaccaatgaaatcatcacaggagccacagta
ggagacttctgggatggatttgaagatgttccaaatcgtttgaaaaatgaaaaagaacca
atggtgttgaaacttaaggactggccaccaggagaagattttagagatatgatgccttcc
aggtttgatgatctgatggccaacattccactgcccgagtacacaaggcgagatggcaaa
ctgaatttggcctctaggctgccaaactactttgttcggccagatctgggccccaagatg
tataatgcttatggattaatcactcctgaagatcggaaatatggaacaacaaatcttcac
ttagatgtatctgatgcagctaatgtcatggtctatgtgggaattcccaaaggacagtgt
gagcaagaagaagaagtccttaagaccatccaagatggagattctgacgaactcacaata
aagcgatttattgaaggaaaagagaagccaggagcactgtggcacatatatgctgcaaag
gacacggagaagataagggaatttcttaaaaaggtatcagaagagcaaggtcaagaaaac
ccagcagaccacgatcctattcatgatcaaagctggtatttagaccgatcattaagaaaa
cgtcttcatcaagagtatggagttcaaggctgggctattgtacagtttcttggggatgtg
gtgtttatcccggcaggagctccacatcaggttcataacttatatagctgcatcaaagtg
gctgaagattttgtttctccagagcatgttaaacactgcttctggcttactcaggaattc
cgatatctgtcacagactcataccaatcacgaagataaattacaggtgaagaatgttatc
taccatgcagtgaaagatgcagttgctatgctgaaagccagtgaatccagttttggcaaa
ccttaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (35)   
   RefGene (28)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (16)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (14)   
DNA sequence (48)   
   RefSeq(nuc) (14)   
   GenBank (17)   
   EMBL (17)   
Protein domain (7)   
   Pfam (7)   
All databases (107)   

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