KEGG   Homo sapiens (human): 55823
Entry
55823             CDS       T01001                                 
Symbol
VPS11, END1, HLD12, DYT32, PEP5, RNF108, hVPS11
Name
(RefSeq) VPS11 core subunit of CORVET and HOPS complexes
  KO
K20179  vacuolar protein sorting-associated protein 11
Organism
hsa  Homo sapiens (human)
Pathway
hsa04140  Autophagy - animal
hsa04148  Efferocytosis
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06532  Autophagy
  Element
N01300  Tethering of late endosomes and lysosomes
N01301  Salmonella SifA to Tethering of late endosomes and lysosomes
N01721  Autophagosome and lysosome fusion, tethering factor
Disease
H00679  Hypomyelinating leukodystrophy
H00831  Primary dystonia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    55823 (VPS11)
   04148 Efferocytosis
    55823 (VPS11)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    55823 (VPS11)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    55823 (VPS11)
Membrane trafficking [BR:hsa04131]
 Endosome - Lysosome transport
  Tethering complex
   CORVET complex
    55823 (VPS11)
   Hops complex
    55823 (VPS11)
SSDB
Motif
Pfam: PEP5_VPS11_N TPR_PEP5_VPS11 VPS11_N VPS11_C Clathrin zf-C3HC4_2 zf-RING_2 zf-C3HC4 zf-rbx1 TPR_GEMI5 zf-C3H2C3 zf-RING_UBOX zf-RING_5 DUF1993 zf-RING_11 zf-ANAPC11 zf-C3HC4_3 zf-RING-like zf_RING_Vps8_fungal DLP_helical DUF5847
Other DBs
NCBI-GeneID: 55823
NCBI-ProteinID: NP_068375
OMIM: 608549
HGNC: 14583
Ensembl: ENSG00000160695
UniProt: Q9H270 A0A087WXL6 B7Z879
Position
11:119067818..119081972
AA seq 941 aa
MAAYLQWRRFVFFDKELVKEPLSNDGAAPGATPASGSAASKFLCLPPGITVCDSGRGSLV
FGDMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEK
RDGGNPLCTRIFPAIPGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQ
ILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIVSGKDYPRVELDTHGCGLRCSALSD
PSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIAHWFRGYLIIVSRDRKVSPKSEFTS
RDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGSLYVLTRDGRVHALQEKDTQTK
LEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEP
SYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSES
EVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQ
AESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANN
PRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFC
DVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLW
EQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQ
KQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGH
SFHQHCFESYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSNDSFSVIAD
YFGRGVFNKLTLLTDPPTARLTSSLEAGLQRDLLMHSRRGT
NT seq 2826 nt   +upstreamnt  +downstreamnt
atggcggcctacctgcagtggcggcgcttcgttttcttcgacaaggagctggtgaaggag
ccgctgagcaatgatggggccgctcccggggccacacctgcttctggatccgctgcttcc
aagttcctttgcctccctcctggcatcactgtctgcgactcaggccgagggagcctggtc
tttggagatatggaaggccagatctggttcttgccacgttccctacagcttacaggcttc
caagcctacaaactacgggtgacacacctgtaccaactgaagcagcacaatattctggca
tctgttggagaagatgaagagggcatcaaccccttggttaagatctggaacctggagaag
agagatggtggcaatccactctgcactcgaatcttccctgctattccaggaacagagcca
actgttgtatcttgtttgactgtccatgaaaatctcaactttatggccattggtttcaca
gatggcagtgttacattgaacaaaggagacatcacccgggaccggcatagcaagacccag
attttgcacaagggcaactatcctgtaactggattggcctttcgccaagcaggaaagacc
actcacttgtttgttgtgacaacagagaacgtccagtcctatatagtttctggaaaagac
taccctcgcgtggagttggacacccatggttgtggcctgcgctgctcagccctaagtgac
ccttctcaggacctgcagttcattgtggccggggatgagtgtgtctacttgtaccagcct
gatgaacgtgggccctgcttcgcctttgagggccataagctcattgcccactggtttaga
ggctaccttatcattgtctcccgtgaccggaaggtttctcccaagtcagagtttaccagc
agggattcacagagctccgacaagcagattctaaacatctatgacctgtgcaacaagttc
atagcctatagcaccgtctttgaggatgtagtggatgtgcttgctgagtggggctccctg
tacgtgctgacgcgggatgggcgggtccacgcactgcaggagaaggacacacagaccaaa
ctggagatgctgtttaagaagaacctatttgagatggcgattaaccttgccaagagccag
catctggacagtgatgggctggcccagattttcatgcagtatggagaccatctctacagc
aagggcaaccacgatggggctgtccagcaatatatccgaaccattggaaagttggagcca
tcctacgtgatccgcaagtttctggatgcccagcgcattcacaacctgactgcctacctg
cagaccctgcaccgacaatccctggccaatgccgaccataccaccctgctcctcaactgc
tataccaagctcaaggacagctcgaagctggaggagttcatcaagaaaaagagtgagagt
gaagtccactttgatgtggagacagccatcaaggtcctccggcaggctggctactactcc
catgccctgtatctggcggagaaccatgcacatcatgagtggtacctgaagatccagcta
gaagacattaagaattatcaggaagcccttcgatacatcggcaagctgccttttgagcag
gcagagagcaacatgaagcgctacggcaagatcctcatgcaccacataccagagcagaca
actcagttgctgaagggactttgtactgattatcggcccagcctcgaaggccgcagcgat
agggaggccccaggctgcagggccaactctgaggagttcatccccatctttgccaataac
ccgcgagagctgaaagccttcctagagcacatgagtgaagtgcagccagactcaccccag
gggatctacgacacactccttgagctgcgactgcagaactgggcccacgagaaggatcca
caggtcaaagagaagcttcacgcagaggccatttccctgctgaagagtggtcgcttctgc
gacgtctttgacaaggccctggtcctgtgccagatgcacgacttccaggatggtgtcctt
tacctttatgagcaggggaagctgttccagcagatcatgcactaccacatgcagcacgag
cagtaccggcaggtcatcagcgtgtgtgagcgccatggggagcaggacccctccttgtgg
gagcaggccctcagctacttcgctcgcaaggaggaggactgcaaggagtatgtggcagct
gtcctcaagcatatcgagaacaagaacctcatgccacctcttctagtggtgcagaccctg
gcccacaactccacagccacactctccgtcatcagggactacctggtccaaaaactacag
aaacagagccagcagattgcacaggatgagctgcgggtgcggcggtaccgagaggagacc
acccgtatccgccaggagatccaagagctcaaggccagtcctaagattttccaaaagacc
aagtgcagcatctgtaacagtgccttggagttgccctcagtccacttcctgtgtggccac
tccttccaccaacactgctttgagagttactcggaaagtgatgctgactgccccacctgc
ctccctgaaaaccggaaggtcatggatatgatccgggcccaggaacagaaacgagatctc
catgatcaattccagcatcagctcaagtgctccaatgacagcttttctgtgattgctgac
tactttggcagaggtgttttcaacaaattgactctgctgaccgaccctcccacagccaga
ctgacctccagcctggaggctgggctgcaacgcgacctactcatgcactccaggaggggc
acttaa

  All links  
Disease (3)   
   OMIM (3)   
Gene (14)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (13)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (44)   
   RefSeq(nuc) (20)   
   GenBank (12)   
   EMBL (12)   
Protein domain (21)   
   Pfam (21)   
All databases (95)   

Download RDF
DBGET integrated database retrieval system