KEGG   Homo sapiens (human): 5586Help
Entry
5586              CDS       T01001                                 

Gene name
PKN2, PAK2, PRK2, PRKCL2, PRO2042, Pak-2, STK7
Definition
(RefSeq) protein kinase N2
  KO
K23691  serine/threonine-protein kinase N2 [EC:2.7.11.13]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04621  NOD-like receptor signaling pathway
hsa05135  Yersinia infection
Network
nt06139  NLR signaling (viruses and bacteria)
  Element
N00866  Yersinia YopM to Pyrin Inflammasome signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    5586 (PKN2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    5586 (PKN2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    5586 (PKN2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    5586 (PKN2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     5586 (PKN2)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: AGC group
  PKN family
   5586 (PKN2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase HR1 Pkinase_Tyr Pkinase_C Kinase-like Uds1 Haspin_kinase C2 Fib_alpha
Motif
Other DBs
NCBI-GeneID: 5586
NCBI-ProteinID: NP_006247
OMIM: 602549
HGNC: 9406
Ensembl: ENSG00000065243
Vega: OTTHUMG00000010074
Pharos: Q16513(Tchem)
UniProt: Q16513
Structure
PDB: 

Position
1p22.2
AA seq 984 aa AA seqDB search
MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKEL
KIKEGAENLRKVTTDKKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPR
TPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLL
QDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVM
KLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVA
ASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWS
PSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQK
FTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFN
PVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQAPV
PTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPG
QDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCC
AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFL
VNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVY
RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDW
WGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRL
GASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPP
REPRILSEEEQEMFRDFDYIADWC
NT seq 2955 nt NT seq  +upstreamnt  +downstreamnt
atggcgtccaaccccgaacggggggagattctgctcacggaactgcagggggattcccga
agtcttccgttttctgagaatgtgagtgctgttcaaaaattagacttttcagatacaatg
gtgcagcagaaattggatgatatcaaggatcgaattaagagagaaataaggaaagaactg
aaaatcaaagaaggagctgaaaatctgaggaaagtcacaacagataaaaaaagtttggct
tatgtagacaacattttgaaaaaatcaaataaaaaattagaagaactacatcacaagctg
caggaattaaatgcacatattgttgtatcagatccagaagatattacagattgcccaagg
actccagatactccaaataatgaccctcgttgttctactagcaacaatagattgaaggcc
ttacaaaaacaattggatatagaacttaaagtaaaacaaggtgcagagaatatgatacag
atgtattcaaatggatcttcaaaggatcggaaactccatggtacagctcagcaactgctc
caggacagcaagacaaaaatagaagtcatacgaatgcagattcttcaggcagtccagact
aatgaattggcttttgataatgcaaaacctgtgataagtcctcttgaacttcggatggaa
gaattaaggcatcattttaggatagagtttgcagtagcagaaggtgcaaagaatgtaatg
aaattacttggctcaggaaaagtaacagacagaaaagcactttcagaagctcaagcaaga
tttaatgaatcaagtcagaagttggaccttttaaagtattcattagagcaaagattaaac
gaagtccccaagaatcatcccaaaagcaggattattattgaagaactttcacttgttgct
gcatcaccaacactaagtccacgtcaaagtatgatatctacgcaaaatcaatatagtaca
ctatccaaaccagcagcactaacaggtactttggaagttcgtcttatgggctgccaagat
atcctagagaatgtccctggacggtcaaaagcaacatcagttgcactgcctggttggagt
ccaagtgaaaccagatcatctttcatgagcagaacgagtaaaagtaaaagcggaagtagt
cgaaatcttctaaaaaccgatgacttgtccaatgatgtctgtgctgttttgaagctcgat
aatactgtggttggccaaactagctggaaacccatttccaatcagtcatgggaccagaag
tttacactggaactggacaggtcacgtgaactggaaatttcagtttattggcgtgattgg
cggtctctgtgtgctgtaaaatttctgaggttagaagattttttagacaaccaacggcat
ggcatgtgtctctatttggaaccacagggtactttatttgcagaggttaccttttttaat
ccagttattgaaagaagaccaaaacttcaaagacaaaagaaaattttttcaaagcaacaa
ggcaaaacatttctcagagctcctcaaatgaatattaatattgccacttggggaaggcta
gtaagaagagctattcctacagtaaatcattctggcaccttcagccctcaagctcctgtg
cctactacagtgccagtggttgatgtacgcatccctcaactagcacctccagctagtgat
tctacagtaaccaaattggactttgatcttgagcctgaacctcctccagccccaccacga
gcttcttctcttggagaaatagatgaatcttctgaattaagagttttggatataccagga
caggattcagagactgtttttgatattcagaatgacagaaatagtatacttccaaaatct
caatctgaatacaagcctgatactcctcagtcaggcctagaatatagtggtattcaagaa
cttgaggacagaagatctcagcaaaggtttcagtttaatctacaagatttcaggtgttgt
gctgtcttgggaagaggacattttggaaaggtgcttttagctgaatataaaaacacaaat
gagatgtttgctataaaagccttaaagaaaggagatattgtggctcgagatgaagtagac
agcctgatgtgtgaaaaaagaatttttgaaactgtgaatagtgtaaggcatccctttttg
gtgaacctttttgcatgtttccaaaccaaagagcatgtttgctttgtaatggaatatgct
gccggtggggacctaatgatgcacattcatactgatgtcttttctgaaccaagagctgta
ttttatgctgcttgtgtagttcttgggttgcagtatttacatgaacacaaaattgtttat
agagatttgaaattggataacttattgctagatacagagggctttgtgaaaattgctgat
tttggtctttgcaaagaaggaatgggatatggagatagaacaagcacattttgtggcact
cctgaatttcttgccccagaagtattaacagaaacttcttatacaagggctgtagattgg
tggggccttggcgtgcttatatatgaaatgcttgttggtgagtctccctttcctggtgat
gatgaagaggaagtttttgacagtattgtaaatgatgaagtaaggtatccaaggttctta
tctacagaagccatttctataatgagaaggctgttaagaagaaatcctgaacggcgcctt
ggggctagcgagaaagatgcagaggatgtaaaaaagcacccatttttccggctaattgat
tggagcgctctgatggacaaaaaagtaaagccaccatttatacctaccataagaggacga
gaagatgttagtaattttgatgatgaatttacctcagaagcacctattctgactccacct
cgagaaccaaggatactttcggaagaggagcaggaaatgttcagagattttgactacatt
gctgattggtgttaa

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