KEGG   Homo sapiens (human): 5586
Entry
5586              CDS       T01001                                 
Symbol
PKN2, PAK2, PRK2, PRKCL2, PRO2042, Pak-2, STK7
Name
(RefSeq) protein kinase N2
  KO
K23691  serine/threonine-protein kinase N2 [EC:2.7.11.13]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04621  NOD-like receptor signaling pathway
hsa05135  Yersinia infection
Network
nt06183  Yersinia
nt06521  NLR signaling
  Element
N00866  Yersinia YopM to Pyrin Inflammasome signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    5586 (PKN2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    5586 (PKN2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    5586 (PKN2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    5586 (PKN2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     5586 (PKN2)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: AGC group
  PKN family
   5586 (PKN2)
SSDB
Motif
Pfam: Pkinase HR1 PK_Tyr_Ser-Thr Pkinase_C Kinase-like Uds1 Haspin_kinase C2 ABC1
Other DBs
NCBI-GeneID: 5586
NCBI-ProteinID: NP_006247
OMIM: 602549
HGNC: 9406
Ensembl: ENSG00000065243
UniProt: Q16513
Structure
Position
1:88684273..88836255
AA seq 984 aa
MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKEL
KIKEGAENLRKVTTDKKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPR
TPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLL
QDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVM
KLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVA
ASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWS
PSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQK
FTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFN
PVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQAPV
PTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPG
QDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCC
AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFL
VNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVY
RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDW
WGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRL
GASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPP
REPRILSEEEQEMFRDFDYIADWC
NT seq 2955 nt   +upstreamnt  +downstreamnt
atggcgtccaaccccgaacggggggagattctgctcacggaactgcagggggattcccga
agtcttccgttttctgagaatgtgagtgctgttcaaaaattagacttttcagatacaatg
gtgcagcagaaattggatgatatcaaggatcgaattaagagagaaataaggaaagaactg
aaaatcaaagaaggagctgaaaatctgaggaaagtcacaacagataaaaaaagtttggct
tatgtagacaacattttgaaaaaatcaaataaaaaattagaagaactacatcacaagctg
caggaattaaatgcacatattgttgtatcagatccagaagatattacagattgcccaagg
actccagatactccaaataatgaccctcgttgttctactagcaacaatagattgaaggcc
ttacaaaaacaattggatatagaacttaaagtaaaacaaggtgcagagaatatgatacag
atgtattcaaatggatcttcaaaggatcggaaactccatggtacagctcagcaactgctc
caggacagcaagacaaaaatagaagtcatacgaatgcagattcttcaggcagtccagact
aatgaattggcttttgataatgcaaaacctgtgataagtcctcttgaacttcggatggaa
gaattaaggcatcattttaggatagagtttgcagtagcagaaggtgcaaagaatgtaatg
aaattacttggctcaggaaaagtaacagacagaaaagcactttcagaagctcaagcaaga
tttaatgaatcaagtcagaagttggaccttttaaagtattcattagagcaaagattaaac
gaagtccccaagaatcatcccaaaagcaggattattattgaagaactttcacttgttgct
gcatcaccaacactaagtccacgtcaaagtatgatatctacgcaaaatcaatatagtaca
ctatccaaaccagcagcactaacaggtactttggaagttcgtcttatgggctgccaagat
atcctagagaatgtccctggacggtcaaaagcaacatcagttgcactgcctggttggagt
ccaagtgaaaccagatcatctttcatgagcagaacgagtaaaagtaaaagcggaagtagt
cgaaatcttctaaaaaccgatgacttgtccaatgatgtctgtgctgttttgaagctcgat
aatactgtggttggccaaactagctggaaacccatttccaatcagtcatgggaccagaag
tttacactggaactggacaggtcacgtgaactggaaatttcagtttattggcgtgattgg
cggtctctgtgtgctgtaaaatttctgaggttagaagattttttagacaaccaacggcat
ggcatgtgtctctatttggaaccacagggtactttatttgcagaggttaccttttttaat
ccagttattgaaagaagaccaaaacttcaaagacaaaagaaaattttttcaaagcaacaa
ggcaaaacatttctcagagctcctcaaatgaatattaatattgccacttggggaaggcta
gtaagaagagctattcctacagtaaatcattctggcaccttcagccctcaagctcctgtg
cctactacagtgccagtggttgatgtacgcatccctcaactagcacctccagctagtgat
tctacagtaaccaaattggactttgatcttgagcctgaacctcctccagccccaccacga
gcttcttctcttggagaaatagatgaatcttctgaattaagagttttggatataccagga
caggattcagagactgtttttgatattcagaatgacagaaatagtatacttccaaaatct
caatctgaatacaagcctgatactcctcagtcaggcctagaatatagtggtattcaagaa
cttgaggacagaagatctcagcaaaggtttcagtttaatctacaagatttcaggtgttgt
gctgtcttgggaagaggacattttggaaaggtgcttttagctgaatataaaaacacaaat
gagatgtttgctataaaagccttaaagaaaggagatattgtggctcgagatgaagtagac
agcctgatgtgtgaaaaaagaatttttgaaactgtgaatagtgtaaggcatccctttttg
gtgaacctttttgcatgtttccaaaccaaagagcatgtttgctttgtaatggaatatgct
gccggtggggacctaatgatgcacattcatactgatgtcttttctgaaccaagagctgta
ttttatgctgcttgtgtagttcttgggttgcagtatttacatgaacacaaaattgtttat
agagatttgaaattggataacttattgctagatacagagggctttgtgaaaattgctgat
tttggtctttgcaaagaaggaatgggatatggagatagaacaagcacattttgtggcact
cctgaatttcttgccccagaagtattaacagaaacttcttatacaagggctgtagattgg
tggggccttggcgtgcttatatatgaaatgcttgttggtgagtctccctttcctggtgat
gatgaagaggaagtttttgacagtattgtaaatgatgaagtaaggtatccaaggttctta
tctacagaagccatttctataatgagaaggctgttaagaagaaatcctgaacggcgcctt
ggggctagcgagaaagatgcagaggatgtaaaaaagcacccatttttccggctaattgat
tggagcgctctgatggacaaaaaagtaaagccaccatttatacctaccataagaggacga
gaagatgttagtaattttgatgatgaatttacctcagaagcacctattctgactccacct
cgagaaccaaggatactttcggaagaggagcaggaaatgttcagagattttgactacatt
gctgattggtgttaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (18)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (40)   
   RefSeq(nuc) (12)   
   GenBank (14)   
   EMBL (14)   
3D Structure (4)   
   PDB (4)   
Protein domain (9)   
   Pfam (9)   
All databases (86)   

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