KEGG   Homo sapiens (human): 55867
Entry
55867             CDS       T01001                                 

Gene name
SLC22A11, OAT4, hOAT4
Definition
(RefSeq) solute carrier family 22 member 11
  KO
K08207  MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 11
Organism
hsa  Homo sapiens (human)
Drug target
Lesinurad (DG01388): D09921 D09922
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    55867 (SLC22A11)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC22: Organic cation/anion/zwitterion transporter
   55867 (SLC22A11)
 Major facilitator superfamily (MFS)
  Organic acid transporters
   Organic cation transporter (OCT) family [TC:2.A.1.19]
    55867 (SLC22A11)
SSDB
Motif
Pfam: Sugar_tr MFS_1
Other DBs
NCBI-GeneID: 55867
NCBI-ProteinID: NP_060954
OMIM: 607097
HGNC: 18120
Ensembl: ENSG00000168065
Vega: OTTHUMG00000045142
Pharos: Q9NSA0(Tclin)
UniProt: Q9NSA0
Position
11q13.1
AA seq 550 aa
MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV
STNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYD
RSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQL
AVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSA
GQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVA
RINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLISY
YGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILANM
LVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMGP
LILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQKSTAAQGNRQ
EAVTVESTSL
NT seq 1653 nt   +upstreamnt  +downstreamnt
atggcgttctcgaagctcttggagcaagccggaggcgtgggcctcttccagaccctgcag
gtgctcaccttcatcctcccctgcctcatgataccttcccagatgctcctggagaacttc
tcagccgccatcccaggccaccgatgctggacacacatgctggacaatggctctgcggtt
tccacaaacatgacccccaaggcccttctgaccatctccatcccgccaggccccaaccag
gggccccaccagtgccgccgcttccgccagccacagtggcagctcttggaccccaatgcc
acggccaccagctggagcgaagctgacacggagccgtgtgtggacggctgggtctatgac
cgcagcgtcttcacctccaccatcgtggccaagtgggacctggtgtgcagctcccagggc
ttgaagcccctaagccagtccatcttcatgtccgggatcctggtgggctcctttatctgg
ggcctcctctcctaccggtttgggaggaagccgatgctgagctggtgctgcctgcagttg
gccgtggcgggcaccagcaccatcttcgccccaacattcgtcatctactgcggcctgcgg
ttcgtggccgcttttgggatggccggcatctttctgagttcactgacactgatggtggag
tggaccacgaccagcaggagggcggtcaccatgacggtggtgggatgtgccttcagcgca
ggccaggcggcgctgggcggcctggcctttgccctgcgggactggaggactctccagctg
gcagcatcagtgcccttctttgccatctccctgatatcctggtggctgccagaatccgcc
cggtggctgattattaagggcaaaccagaccaagcacttcaggagctcagaaaggtggcc
aggataaatggccacaaggaggccaagaacctgaccatagaggtgctgatgtccagcgtg
aaggaggaggtggcctctgcaaaggagccgcggtcggtgctggacctgttctgcgtgccc
gtgctccgctggaggagctgcgccatgctggtggtgaatttctctctattgatctcctac
tatgggctggtcttcgacctgcagagcctgggccgtgacatcttcctcctccaggccctc
ttcggggccgtggacttcctgggccgggccaccactgccctcttgctcagtttccttggc
cgccgcaccatccaggcgggttcccaggccatggccggcctcgccattctagccaacatg
ctggtgccgcaagatttgcagaccctgcgtgtggtctttgctgtgctgggaaagggatgt
tttgggataagcctaacctgcctcaccatctacaaggctgaactctttccaacgccagtg
cggatgacagcagatggcattctgcatacagtgggccggctgggggctatgatgggtccc
ctgatcctgatgagccgccaagccctgcccctgctgcctcctctcctctatggcgttatc
tccattgcttccagcctggttgtgctgttcttcctcccggagacccagggacttccgctc
cctgacactatccaggacctggagagccagaaatcaacagcagcccagggcaaccggcaa
gaggccgtcactgtggaaagtacctcgctctag

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Ontology (2)   
   KEGG BRITE (2)   
Disease (1)   
   OMIM (1)   
Drug (2)   
   KEGG DRUG (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (29)   
   RefSeq(nuc) (3)   
   GenBank (13)   
   EMBL (13)   
Protein domain (2)   
   Pfam (2)   
All databases (63)   

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