KEGG   Homo sapiens (human): 55879
Entry
55879             CDS       T01001                                 
Symbol
GABRQ, THETA
Name
(RefSeq) gamma-aminobutyric acid type A receptor subunit theta
  KO
K05192  gamma-aminobutyric acid receptor subunit theta
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04082  Neuroactive ligand signaling
hsa04723  Retrograde endocannabinoid signaling
hsa04727  GABAergic synapse
hsa05032  Morphine addiction
hsa05033  Nicotine addiction
Drug target
Abecarnil: D02594
Adinazolam (DG00911): D02770 D02771
Adipiplon: D08840
Alpidem: D02833
Alprazolam: D00225<JP/US>
Aminobutyric acid: D00058<JP>
Amobarbital (DG00916): D00555 D02252
Aprobarbital: D00698
Barbexaclone: D07298
Barbital: D01740
Bretazenil: D03155
Brexanolone: D11149
Bromazepam: D01245<JP>
Brotizolam: D01744<JP>
Butabarbital (DG01308): D00699 D03180
Butobarbital: D02618
Cenobamate: D11150<US>
Chlordiazepoxide (DG00908): D00267<JP> D00693<US>
Cinolazepam: D07328
Cipepofol: D12449
Clobazam: D01253<JP/US>
Clonazepam: D00280<JP/US>
Clotiazepam: D01328<JP>
Cloxazolam: D01268<JP>
Darigabat: D12146
Delorazepam: D07784
Dextofisopam: D03737
Diazepam: D00293<JP/US>
Estazolam: D00311<JP/US>
Eszopiclone: D02624<JP/US>
Ethyl loflazepate: D01293<JP>
Etizolam: D01514<JP>
Fludiazepam: D01354
Flumazenil: D00697<JP/US>
Flunitrazepam: D01230<JP>
Flurazepam (DG00919): D00329 D00695<US> D01408<JP>
Flutazolam: D01286
Flutoprazepam: D01279
Gaboxadol: D04282
Ganaxolone: D04300<US>
Glutethimide: D00532
Halazepam: D00338
Haloxazolam: D01758<JP>
Hexobarbital: D01071
Indiplon: D02640
Iomazenil: D02283<JP>
Ketazolam: D04650
Levotofisopam: D04721
Loprazolam (DG00921): D07326 D08145
Lorazepam: D00365<JP/US>
Lormetazepam: D01657<JP>
Medazepam (DG00909): D01292<JP> D04882
Meprobamate: D00376<US>
Metharbital: D01382
Methylphenobarbital: D00700
Mexazolam: D01316<JP>
Midazolam (DG00920): D00550<JP/US> D00696<US> D05028
Nimetazepam: D01593
Nitrazepam: D00531<JP>
Nordazepam: D08283
Ocinaplon: D02617
Oxazepam: D00464<US>
Oxazolam: D01278<JP>
Pagoclone: D02616
Panadiplon: D05346
Pazinaclone: D05378
Pentobarbital (DG00915): D00499 D00500<US> D02253<JP>
Phenobarbital (DG00845): D00506<JP> D00701<JP/US> D08356
Potassium clorazepate (DG01218): D00694<JP/US> D03562
Prazepam: D00470
Propofol (DG00797): D00549<JP/US> D04257
Quazepam: D00457<JP/US>
Remimazolam (DG03105): D10194<JP/US> D11788
Rilmazafone (DG01307): D01564<JP> D08481
Sarmazenil: D08507
Secobarbital (DG00917): D00430 D01310
Suritozole: D05980
Talbutal: D06887
Temazepam: D00370<US>
Thiamylal (DG01377): D00713<JP> D06106
Thiopental (DG00790): D00714<JP>
Tofisopam: D01254<JP>
Topiramate: D00537<JP/US>
Triazolam: D00387<JP/US>
Zolpidem (DG00922): D00706<JP/US> D08690
Zopiclone: D01372<JP>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    55879 (GABRQ)
   04082 Neuroactive ligand signaling
    55879 (GABRQ)
 09150 Organismal Systems
  09156 Nervous system
   04727 GABAergic synapse
    55879 (GABRQ)
   04723 Retrograde endocannabinoid signaling
    55879 (GABRQ)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    55879 (GABRQ)
   05033 Nicotine addiction
    55879 (GABRQ)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    55879 (GABRQ)
Ion channels [BR:hsa04040]
 Ligand-gated channels
  GABA-A
   55879 (GABRQ)
SSDB
Motif
Pfam: Neur_chan_LBD Neur_chan_memb
Other DBs
NCBI-GeneID: 55879
NCBI-ProteinID: NP_061028
OMIM: 300349
HGNC: 14454
Ensembl: ENSG00000268089
UniProt: Q9UN88
Position
X:152637895..152658965
AA seq 632 aa
MGIRGMLRAAVILLLIRTWLAEGNYPSPIPKFHFEFSSAVPEVVLNLFNCKNCANEAVVQ
KILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQTWKDSRLA
YYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTT
AACSLDLHKFPMDKQACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTI
TSKEVYFYTGSYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTI
GLTSMLILTTIDSHLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYLFYSRGPRR
QPRRHRRPRRVIARYRYQQVVVGNVQDGLINVEDGVSSLPITPAQAPLASPESLGSLTST
SEQAQLATSESLSPLTSLSGQAPLATGESLSDLPSTSEQARHSYGVRFNGFQADDSIIPT
EIRNRVEAHGHGVTHDHEDSNESLSSDERHGHGPSGKPMLHHGEKGVQEAGWDLDDNNDK
SDCLAIKEQFKCDTNSTWGLNDDELMAHGQEKDSSSESEDSCPPSPGCSFTEGFSFDLFN
PDYVPKVDKWSRFLFPLAFGLFNIVYWVYHMY
NT seq 1899 nt   +upstreamnt  +downstreamnt
atgggcatccgaggcatgctgcgagccgcagtgatcctgctgctcatcaggacctggctc
gcggagggcaactaccccagtcccatcccgaaattccacttcgagttctcctctgctgtg
cccgaagtcgtcctgaacctcttcaactgcaaaaattgtgcaaatgaagctgtggttcaa
aagattttggacagggtgctgtcaagatacgatgtccgcctgagaccgaattttggaggt
gcccctgtgcctgtgagaatatctatttatgtcacgagcattgaacagatctcagaaatg
aatatggactacacgatcacgatgttttttcatcagacttggaaagattcacgcttagca
tactatgagaccaccctgaacttgaccctggactatcggatgcatgagaagttgtgggtc
cctgactgctactttctgaacagcaaggatgctttcgtgcatgatgtgactgtggagaat
cgcgtgtttcagcttcacccagatggaacggtgcggtacggcatccgactcaccactaca
gcagcttgttccctggatctgcataaattccctatggacaagcaggcctgcaacctggtg
gtagagagctatggttacacggttgaagacatcatattattctgggatgacaatgggaac
gccatccacatgactgaggagctgcatatccctcagttcactttcctgggaaggacgatt
actagcaaggaggtgtatttctacacaggttcctacatacgcctgatactgaagttccag
gttcagagggaagttaacagctaccttgtgcaagtctactggcctactgtcctcaccact
attacctcttggatatcgttttggatgaactatgattcctctgcagccagggtgacaatt
ggcttaacttcaatgctcatcctgaccaccatcgactcacatctgcgggataagctcccc
aacatttcctgtatcaaggccattgatatctatatcctcgtgtgcttgttctttgtgttc
ctgtccttgctggagtatgtctacatcaactatcttttctacagtcgaggacctcggcgc
cagcctaggcgacacaggagaccccgaagagtcattgcccgctaccgctaccagcaagtg
gtggtaggaaacgtgcaggatggcctgattaacgtggaagacggagtcagctctctcccc
atcaccccagcgcaggcccccctggcaagcccggaaagcctcggttctttgacgtccacc
tccgagcaggcccagctggccacctcggaaagcctcagcccactcacttctctctcaggc
caggcccccctggccactggagaaagcctgagcgatctcccctccacctcagagcaggcc
cggcacagctatggtgttcgctttaatggtttccaggctgatgacagtattattcctacc
gaaatccgcaaccgtgtcgaagcccatggccatggtgttacccatgaccatgaagattcc
aatgagagcttgagctcggatgagcgccatggccatggccccagtgggaagcccatgctt
caccatggcgagaagggtgtgcaagaagcaggctgggaccttgatgacaacaatgacaag
agcgactgccttgccattaaggagcaattcaagtgtgatactaacagtacctggggcctt
aatgatgatgagctcatggcccatggccaagagaaggacagtagctcagagtctgaggat
agttgccccccaagccctgggtgctccttcactgaagggttctccttcgatctctttaat
cctgactacgtcccaaaggtcgacaagtggtcccggttcctcttccctctggcctttggg
ttgttcaacattgtttactgggtataccatatgtattag

  All links  
Disease (1)   
   OMIM (1)   
Gene (27)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (14)   
   RefSeq(nuc) (4)   
   GenBank (5)   
   EMBL (5)   
Protein domain (2)   
   Pfam (2)   
All databases (50)   

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