KEGG   Homo sapiens (human): 55902
Entry
55902             CDS       T01001                                 

Gene name
ACSS2, ACAS2, ACECS, ACS, ACSA, AceCS1, dJ1161H23.1
Definition
(RefSeq) acyl-CoA synthetase short chain family member 2
  KO
K01895  acetyl-CoA synthetase [EC:6.2.1.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00010  Glycolysis / Gluconeogenesis
hsa00620  Pyruvate metabolism
hsa00630  Glyoxylate and dicarboxylate metabolism
hsa00640  Propanoate metabolism
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    55902 (ACSS2)
   00620 Pyruvate metabolism
    55902 (ACSS2)
   00630 Glyoxylate and dicarboxylate metabolism
    55902 (ACSS2)
   00640 Propanoate metabolism
    55902 (ACSS2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:hsa01004]
    55902 (ACSS2)
Enzymes [BR:hsa01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.1  acetate---CoA ligase
     55902 (ACSS2)
Lipid biosynthesis proteins [BR:hsa01004]
 Acyl-CoA synthetase
  Short/medium chain acyl-CoA synthetase
   55902 (ACSS2)
SSDB
Motif
Pfam: AMP-binding AMP-binding_C ACAS_N
Other DBs
NCBI-GeneID: 55902
NCBI-ProteinID: NP_061147
OMIM: 605832
HGNC: 15814
Ensembl: ENSG00000131069
Vega: OTTHUMG00000032317
Pharos: Q9NR19(Tbio)
UniProt: Q9NR19 Q6DKJ3
Position
20q11.22
AA seq 701 aa
MGLPEERVRSGSGSRGQEEAGAGGRARSWSPPPEVSRSAHVPSLQRYRELHRRSVEEPRE
FWGDIAKEFYWKTPCPGPFLRYNFDVTKGKIFIEWMKGATTNICYNVLDRNVHEKKLGDK
VAFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAMLAC
ARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEALQKCQEK
GFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQISWNQGIDLWWHELMQEAGDEC
EPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIG
WITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFG
DEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPG
ATPMKPGSATFPFFGVAPAILNESGEELEGEAEGYLVFKQPWPGIMRTVYGNHERFETTY
FKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVV
GHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSG
KIMRRVLRKIAQNDHDLGDMSTVADPSVISHLFSHRCLTIQ
NT seq 2106 nt   +upstreamnt  +downstreamnt
atggggcttcctgaggagcgggtccggagcggcagcgggagccggggccaggaggaagct
ggagccggaggccgggcgcggagttggtctccgccgcccgaggtcagccgctccgcgcac
gtcccctcgctgcagcgctaccgcgagctgcaccggcgctccgtggaggagccgcgggaa
ttctggggagacattgccaaggaattttactggaagactccatgccctggcccattcctt
cggtacaactttgatgtgactaaagggaaaatcttcattgagtggatgaaaggagcaact
accaacatctgctacaatgtactggatcgaaatgtccatgagaaaaagcttggagataaa
gttgctttttactgggagggcaatgagccaggggagaccactcagatcacataccatcag
cttctggtccaagtgtgtcagttcagcaatgttctccgaaaacagggcattcagaagggg
gaccgagtggccatctacatgcctatgatcccagagcttgtggtggccatgctggcatgt
gcccgcattggggctttgcactccattgtgtttgcaggcttctcttcagagtctctatgt
gaacggatcttggattccagctgcagtcttctcatcactacagatgccttctacaggggg
gaaaagcttgtgaacctgaaggagctggctgacgaggccctgcagaagtgtcaggagaag
ggtttcccagtaagatgctgcattgtggtcaagcacctggggcgggcagagctcggcatg
ggtgactccaccagccagtcccccccaattaagaggtcatgcccagatgtgcagatctca
tggaaccaagggattgacttgtggtggcatgagctcatgcaagaggcaggggatgagtgt
gagcccgagtggtgtgatgccgaggacccactcttcatcctgtacaccagtggctccaca
ggcaaacccaagggtgtggttcacacagttgggggctacatgctctatgtagccacaacc
ttcaagtatgtgtttgacttccatgcagaggatgtgttctggtgcacggcagacattggt
tggatcactggtcattcctacgtcacctatgggccactggccaatggtgccaccagtgtt
ttgtttgaggggattcccacatatccggacgtgaaccgcctgtggagcattgtggacaaa
tacaaggtgaccaagttctacacagcacccacagccatccgtctgctcatgaagtttgga
gatgagcctgtcaccaagcatagccgggcatccttgcaggtgttaggcacagtgggtgaa
cccatcaaccctgaggcctggctatggtaccaccgggtggtaggtgcccagcgctgcccc
atcgtggacaccttctggcaaacagagacaggtggccacatgttgactccccttcctggt
gccacacccatgaaacccggttctgctactttcccattctttggtgtagctcctgcaatc
ctgaatgagtccggggaagagttggaaggtgaagctgaaggttatctggtgttcaagcag
ccctggccagggatcatgcgcacagtctatgggaaccacgaacgctttgagacaacctac
tttaagaagtttcctggatactatgttacaggagatggctgccagcgggaccaggatggc
tattactggatcactggcaggattgatgacatgctcaatgtatctggacacctgctgagt
acagcagaggtggagtcagcacttgtggaacatgaggctgttgcagaggcagctgtggtg
ggccaccctcatcctgtgaagggtgaatgcctctactgctttgtcaccttgtgtgatggc
cacaccttcagccccaagctcaccgaggagctcaagaagcagattagagaaaagattggc
cccattgccacaccagactacatccagaatgcacctggcttgcctaaaacccgctcaggg
aaaatcatgaggcgagtgcttcggaagattgctcagaatgaccatgacctcggggacatg
tctactgtggctgacccatctgtcatcagtcacctcttcagccaccgctgcctgaccatc
cagtga

KEGG   Homo sapiens (human): 84532
Entry
84532             CDS       T01001                                 

Gene name
ACSS1, ACAS2L, ACECS1, AceCS2L
Definition
(RefSeq) acyl-CoA synthetase short chain family member 1
  KO
K01895  acetyl-CoA synthetase [EC:6.2.1.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00010  Glycolysis / Gluconeogenesis
hsa00620  Pyruvate metabolism
hsa00630  Glyoxylate and dicarboxylate metabolism
hsa00640  Propanoate metabolism
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    84532 (ACSS1)
   00620 Pyruvate metabolism
    84532 (ACSS1)
   00630 Glyoxylate and dicarboxylate metabolism
    84532 (ACSS1)
   00640 Propanoate metabolism
    84532 (ACSS1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:hsa01004]
    84532 (ACSS1)
Enzymes [BR:hsa01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.1  acetate---CoA ligase
     84532 (ACSS1)
Lipid biosynthesis proteins [BR:hsa01004]
 Acyl-CoA synthetase
  Short/medium chain acyl-CoA synthetase
   84532 (ACSS1)
SSDB
Motif
Pfam: AMP-binding AMP-binding_C ACAS_N
Other DBs
NCBI-GeneID: 84532
NCBI-ProteinID: NP_115890
OMIM: 614355
HGNC: 16091
Ensembl: ENSG00000154930
Vega: OTTHUMG00000032112
Pharos: Q9NUB1(Tbio)
UniProt: Q9NUB1
Position
20p11.21
AA seq 689 aa
MAARTLGRGVGRLLGSLRGLSGQPARPPCGVSAPRRAASGPSGSAPAVAAAAAQPGSYPA
LSAQAAREPAAFWGPLARDTLVWDTPYHTVWDCDFSTGKIGWFLGGQLNVSVNCLDQHVR
KSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVA
AMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVK
HCPTVQHVLVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGM
PKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLF
ESTPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSVGEPI
NCEAWEWLHRVVGDSRCTLVDTWWQTETGGICIAPRPSEEGAEILPAMAMRPFFGIVPVL
MDEKGSVVEGSNVSGALCISQAWPGMARTIYGDHQRFVDAYFKAYPGYYFTGDGAYRTEG
GYYQITGRMDDVINISGHRLGTAEIEDAIADHPAVPESAVIGYPHDIKGEAAFAFIVVKD
SAGDSDVVVQELKSMVATKIAKYAVPDEILVVKRLPKTRSGKVMRRLLRKIITSEAQELG
DTTTLEDPSIIAEILSVYQKCKDKQAAAK
NT seq 2070 nt   +upstreamnt  +downstreamnt
atggcggcgcgcaccctgggccgcggcgtcgggaggctgctgggcagcctgcgagggctc
tcggggcagcccgcgcggccgccgtgcggggtgagcgcgccgcgcagggcggcctcggga
ccctcgggcagcgctcccgcagttgcagcagcagcagcacagccaggctcgtatcccgcg
ctgagtgcacaggcagcccgggagccggccgccttctgggggcctctggcgcgggacact
ctcgtgtgggacaccccctaccacaccgtctgggactgcgacttcagcactggcaagatc
ggctggttcctgggaggccagttaaatgtctctgtcaactgcttggaccagcatgttcgg
aagtcccccgagagcgttgctttgatctgggagcgcgatgagcctggaacggaagtgagg
atcacctacagggaactactggagaccacgtgccgcctggccaacacgctgaagaggcat
ggagtccaccgtggggaccgtgttgccatctacatgcccgtgtccccattggctgtggca
gcaatgctggcctgtgccaggatcggagctgtccacacagtcatctttgctggcttcagt
gcagagtccttggctgggaggatcaatgatgccaagtgcaaggtggttatcaccttcaac
caaggactccggggtgggcgcgtggtggagctgaagaaaatagtggatgaggctgtgaag
cactgccccaccgtgcagcatgtcctggtggctcacaggacagacaacaaggtccacatg
ggggatctggacgtcccgctggagcaggaaatggccaaggaggaccctgtttgcgcccca
gagagcatgggcagtgaggacatgctcttcatgctgtacacctcagggagcaccggaatg
cccaagggcatcgtccatacccaggcaggctacctgctctatgccgccctgactcacaag
cttgtgtttgaccaccagccaggtgacatctttggctgtgtggccgacatcggttggatt
acaggacacagctacgtggtgtatgggcctctctgcaatggtgccaccagcgtccttttt
gagagcaccccagtttatcccaatgctggtcggtactgggagacagtagagaggttgaag
atcaatcagttctatggcgccccaacggctgtccggctgttgctgaaatacggtgatgcc
tgggtgaagaagtatgatcgctcctccctgcggaccctggggtcagtgggagagcccatc
aactgtgaggcctgggagtggcttcacagggtggtgggggacagcaggtgcacgctggtg
gacacctggtggcagacagaaacaggtggcatctgcatcgcaccacggccctcggaagaa
ggggcggaaatcctccctgccatggcgatgaggcccttctttggcatcgtccccgtcctc
atggatgagaagggcagcgtcgtggagggcagcaacgtctccggggccctgtgcatctcc
caggcctggccgggcatggccaggaccatctatggcgaccaccagcgatttgtggacgcc
tacttcaaggcctacccaggctattacttcactggagacggggcttaccgaactgagggc
ggctattaccagatcacagggcggatggatgatgtcatcaacatcagtggccaccggctg
gggaccgcagagattgaggacgccatcgccgaccaccctgcagtaccagaaagtgctgtc
attggctacccccacgacatcaaaggagaagctgcctttgccttcattgtggtgaaagat
agtgcgggtgactcagatgtggtggtgcaggagctcaagtccatggtggccaccaagatc
gccaaatatgctgtgcctgatgagatcctggtggtgaaacgtcttccaaaaaccaggtct
gggaaggtcatgcggcggctcctgaggaagatcatcactagtgaggcccaggagctggga
gacactaccaccttggaggaccccagcatcatcgcagagatcctgagtgtctaccagaag
tgcaaggacaagcaggctgctgctaagtga

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