KEGG   Homo sapiens (human): 5641Help
Entry
5641              CDS       T01001                                 

Gene name
LGMN, AEP, LGMN1, PRSC1
Definition
(RefSeq) legumain
  KO
K01369  legumain [EC:3.4.22.34]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04142  Lysosome
hsa04612  Antigen processing and presentation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Cellular Processes
  Transport and catabolism
   04142 Lysosome
    5641 (LGMN)
 Organismal Systems
  Immune system
   04612 Antigen processing and presentation
    5641 (LGMN)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.34  legumain
     5641 (LGMN)
Peptidases [BR:hsa01002]
 Cysteine Peptidases
  Family C13: legumain family
   5641 (LGMN)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Peptidase_C13 DUF2675
Motif
Other DBs
NCBI-GeneID: 5641
NCBI-ProteinID: NP_001008530
OMIM: 602620
HGNC: 9472
Ensembl: ENSG00000100600
Vega: OTTHUMG00000171199
Pharos: Q99538(Tchem)
UniProt: Q99538 Q53XC6
Structure
PDB: 

Position
14q32.12
AA seq 433 aa AA seqDB search
MVWKVAVFLSVALGIGAVPIDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNG
IPDEQIVVMMYDDIAYSEDNPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGD
AEAVKGIGSGKVLKSGPQDHVFIYFTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYR
KMVFYIEACESGSMMNHLPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMED
SDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVT
HLDLTPSPDVPLTIMKRKLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASE
AEVEQLLSERAPLTGHSCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHR
IKLSMDHVCLGHY
NT seq 1302 nt NT seq  +upstreamnt  +downstreamnt
atggtttggaaagtagctgtattcctcagtgtggccctgggcattggtgccgttcctata
gatgatcctgaagatggaggcaagcactgggtggtgatcgtggcaggttcaaatggctgg
tataattataggcaccaggcagacgcgtgccatgcctaccagatcattcaccgcaatggg
attcctgacgaacagatcgttgtgatgatgtacgatgacattgcttactctgaagacaat
cccactccaggaattgtgatcaacaggcccaatggcacagatgtctatcagggagtcccg
aaggactacactggagaggatgttaccccacaaaatttccttgctgtgttgagaggcgat
gcagaagcagtgaagggcataggatccggcaaagtcctgaagagtggcccccaggatcac
gtgttcatttacttcactgaccatggatctactggaatactggtttttcccaatgaagat
cttcatgtaaaggacctgaatgagaccatccattacatgtacaaacacaaaatgtaccga
aagatggtgttctacattgaagcctgtgagtctgggtccatgatgaaccacctgccggat
aacatcaatgtttatgcaactactgctgccaaccccagagagtcgtcctacgcctgttac
tatgatgagaagaggtccacgtacctgggggactggtacagcgtcaactggatggaagat
tcggacgtggaagatctgactaaagagaccctgcacaagcagtaccacctggtaaaatcg
cacaccaacaccagccacgtcatgcagtatggaaacaaaacaatctccaccatgaaagtg
atgcagtttcagggtatgaaacgcaaagccagttctcccgtccccctacctccagtcaca
caccttgacctcacccccagccctgatgtgcctctcaccatcatgaaaaggaaactgatg
aacaccaatgatctggaggagtccaggcagctcacggaggagatccagcggcatctggat
gccaggcacctcattgagaagtcagtgcgtaagatcgtctccttgctggcagcgtccgag
gctgaggtggagcagctcctgtccgagagagccccgctcacggggcacagctgctaccca
gaggccctgctgcacttccggacccactgcttcaactggcactcccccacgtacgagtat
gcgttgagacatttgtacgtgctggtcaacctttgtgagaagccgtatccgcttcacagg
ataaaattgtccatggaccacgtgtgccttggtcactactga

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