KEGG   Homo sapiens (human): 5644
Entry
5644              CDS       T01001                                 

Gene name
PRSS1, TRP1, TRY1, TRY4, TRYP1
Definition
(RefSeq) serine protease 1
  KO
K01312  trypsin [EC:3.4.21.4]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04972  Pancreatic secretion
hsa04974  Protein digestion and absorption
hsa05164  Influenza A
Disease
H00933  Hereditary pancreatitis
Drug target
Ulinastatin: D05183<JP>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    5644 (PRSS1)
 09150 Organismal Systems
  09154 Digestive system
   04972 Pancreatic secretion
    5644 (PRSS1)
   04974 Protein digestion and absorption
    5644 (PRSS1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    5644 (PRSS1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    5644 (PRSS1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5644 (PRSS1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.4  trypsin
     5644 (PRSS1)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S1: chymotrypsin family
   5644 (PRSS1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   5644 (PRSS1)
SSDB
Motif
Pfam: Trypsin Trypsin_2 DUF1986
Other DBs
NCBI-GeneID: 5644
NCBI-ProteinID: NP_002760
OMIM: 276000
HGNC: 9475
Ensembl: ENSG00000204983
Vega: OTTHUMG00000158923
Pharos: P07477(Tclin)
UniProt: P07477
Structure
PDB: 
2RA3 4WWY 4WXV 1FXY 1TRN

Position
7q34
AA seq 247 aa
MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
NT seq 744 nt   +upstreamnt  +downstreamnt
atgaatccactcctgatccttacctttgtggcagctgctcttgctgccccctttgatgat
gatgacaagatcgttgggggctacaactgtgaggagaattctgtcccctaccaggtgtcc
ctgaattctggctaccacttctgtggtggctccctcatcaacgaacagtgggtggtatca
gcaggccactgctacaagtcccgcatccaggtgagactgggagagcacaacatcgaagtc
ctggaggggaatgagcagttcatcaatgcagccaagatcatccgccacccccaatacgac
aggaagactctgaacaatgacatcatgttaatcaagctctcctcacgtgcagtaatcaac
gcccgcgtgtccaccatctctctgcccaccgcccctccagccactggcacgaagtgcctc
atctctggctggggcaacactgcgagctctggcgccgactacccagacgagctgcagtgc
ctggatgctcctgtgctgagccaggctaagtgtgaagcctcctaccctggaaagattacc
agcaacatgttctgtgtgggcttccttgagggaggcaaggattcatgtcagggtgattct
ggtggccctgtggtctgcaatggacagctccaaggagttgtctcctggggtgatggctgt
gcccagaagaacaagcctggagtctacaccaaggtctacaactatgtgaaatggattaag
aacaccatagctgccaatagctaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (1)   
   KEGG DRUG (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (38)   
   RefSeq(nuc) (2)   
   GenBank (18)   
   EMBL (18)   
Protein domain (3)   
   Pfam (3)   
All databases (71)   

Download RDF
KEGG   Homo sapiens (human): 5645
Entry
5645              CDS       T01001                                 

Gene name
PRSS2, TRY2, TRY8, TRYP2
Definition
(RefSeq) serine protease 2
  KO
K01312  trypsin [EC:3.4.21.4]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04972  Pancreatic secretion
hsa04974  Protein digestion and absorption
hsa05164  Influenza A
Disease
H00933  Hereditary pancreatitis
Drug target
Ulinastatin: D05183<JP>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    5645 (PRSS2)
 09150 Organismal Systems
  09154 Digestive system
   04972 Pancreatic secretion
    5645 (PRSS2)
   04974 Protein digestion and absorption
    5645 (PRSS2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    5645 (PRSS2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    5645 (PRSS2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5645 (PRSS2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.4  trypsin
     5645 (PRSS2)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S1: chymotrypsin family
   5645 (PRSS2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   5645 (PRSS2)
SSDB
Motif
Pfam: Trypsin Trypsin_2 DUF1986
Other DBs
NCBI-GeneID: 5645
NCBI-ProteinID: NP_002761
OMIM: 601564
HGNC: 9483
Ensembl: ENSG00000275896
Vega: OTTHUMG00000158904
Pharos: P07478(Tchem)
UniProt: P07478 Q5NV56 Q6PK75
Position
7q34
AA seq 247 aa
MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVIN
SRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKIT
NNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIK
DTIAANS
NT seq 744 nt   +upstreamnt  +downstreamnt
atgaatctacttctgatccttacctttgttgcagctgctgttgctgccccctttgatgat
gatgacaagatcgttgggggctacatctgtgaggagaattctgtcccctaccaggtgtcc
ttgaattctggctaccacttctgcggtggctccctcatcagcgaacagtgggtggtgtca
gcaggtcactgctacaagtcccgcatccaggtgagactgggagagcacaacatcgaagtc
ctggaggggaatgaacagttcatcaatgcggccaagatcatccgccaccccaaatacaac
agccggactctggacaatgacatcctgctgatcaagctctcctcacctgccgtcatcaat
tcccgcgtgtccgccatctctctgcccactgcccctccagctgctggcaccgagtccctc
atctccggctggggcaacactctgagttctggtgccgactacccagacgagctgcagtgc
ctggatgctcctgtgctgagccaggctgagtgtgaagcctcctaccctggaaagattacc
aacaacatgttctgtgtgggcttcctcgagggaggcaaggattcctgccagggtgattct
ggtggccctgtggtctccaatggagagctccaaggaattgtctcctggggctatggctgt
gcccagaagaacaggcctggagtctacaccaaggtctacaactatgtggactggattaag
gacaccatagctgccaacagctaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (1)   
   KEGG DRUG (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (25)   
   RefSeq(nuc) (3)   
   GenBank (11)   
   EMBL (11)   
Protein domain (3)   
   Pfam (3)   
All databases (62)   

Download RDF
KEGG   Homo sapiens (human): 5646
Entry
5646              CDS       T01001                                 

Gene name
PRSS3, MTG, PRSS4, T9, TRY3, TRY4
Definition
(RefSeq) serine protease 3
  KO
K01312  trypsin [EC:3.4.21.4]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04972  Pancreatic secretion
hsa04974  Protein digestion and absorption
hsa05164  Influenza A
Drug target
Ulinastatin: D05183<JP>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    5646 (PRSS3)
 09150 Organismal Systems
  09154 Digestive system
   04972 Pancreatic secretion
    5646 (PRSS3)
   04974 Protein digestion and absorption
    5646 (PRSS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    5646 (PRSS3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    5646 (PRSS3)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5646 (PRSS3)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.4  trypsin
     5646 (PRSS3)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S1: chymotrypsin family
   5646 (PRSS3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   5646 (PRSS3)
SSDB
Motif
Pfam: Trypsin DUF1986
Other DBs
NCBI-GeneID: 5646
NCBI-ProteinID: NP_001184026
OMIM: 613578
HGNC: 9486
Ensembl: ENSG00000010438
Vega: OTTHUMG00000019798
Pharos: P35030(Tchem)
UniProt: P35030 Q7Z5F4
Structure
PDB: 

Position
9p13.3
AA seq 261 aa
MHMRETSGFTLKKGRSAPLVFHPPDALIAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSH
FCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDN
DIMLIKLSSPAVINARVSTISLPTTPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVL
TQAECKASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRP
GVYTKVYNYVDWIKDTIAANS
NT seq 786 nt   +upstreamnt  +downstreamnt
atgcacatgagagagacaagtggcttcacattgaagaaggggaggagtgcgccattggtt
ttccatcctccagatgcactgattgctgtcccctttgacgatgatgacaagattgttggg
ggctacacctgtgaggagaattctctcccctaccaggtgtccctgaattctggctcccac
ttctgcggtggctccctcatcagcgaacagtgggtggtatcagcagctcactgctacaag
acccgcatccaggtgagactgggagagcacaacatcaaagtcctggaggggaatgagcag
ttcatcaatgcggccaagatcatccgccaccctaaatacaacagggacactctggacaat
gacatcatgctgatcaaactctcctcacctgccgtcatcaatgcccgcgtgtccaccatc
tctctgcccaccacccctccagctgctggcactgagtgcctcatctccggctggggcaac
actctgagctttggtgctgactacccagacgagctgaagtgcctggatgctccggtgctg
acccaggctgagtgtaaagcctcctaccctggaaagattaccaacagcatgttctgtgtg
ggcttccttgagggaggcaaggattcctgccagcgtgactctggtggccctgtggtctgc
aacggacagctccaaggagttgtctcctggggccatggctgtgcctggaagaacaggcct
ggagtctacaccaaggtctacaactatgtggactggattaaggacaccatcgctgccaac
agctaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (25)   
   RefSeq(nuc) (5)   
   GenBank (10)   
   EMBL (10)   
Protein domain (2)   
   Pfam (2)   
All databases (65)   

Download RDF
DBGET integrated database retrieval system