Entry |
|
Symbol |
PSMB8, ALDD, D6S216, D6S216E, JMP, LMP7, NKJO, PRAAS1, PSMB5i, RING10
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Name |
(RefSeq) proteasome 20S subunit beta 8
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KO |
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Organism |
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Pathway |
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Disease |
H01741 | Autoinflammation lipodystrophy and dermatosis syndrome |
H02532 | Proteasome-associated autoinflammatory syndrome |
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Drug target |
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Brite |
KEGG Orthology (KO) [BR:hsa00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03050 Proteasome
5696 (PSMB8)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:hsa01002]
5696 (PSMB8)
09182 Protein families: genetic information processing
03051 Proteasome [BR:hsa03051]
5696 (PSMB8)
Enzymes [BR:hsa01000]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.25 Threonine endopeptidases
3.4.25.1 proteasome endopeptidase complex
5696 (PSMB8)
Peptidases and inhibitors [BR:hsa01002]
Threonine peptidases
Family T1: proteasome family
5696 (PSMB8)
Proteasome [BR:hsa03051]
Eukaryotic proteasome
Core particles (20S proteasome)
beta type subunits
5696 (PSMB8)
|
SSDB |
|
Motif |
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Other DBs |
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Structure |
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Position |
6:complement(32840717..32844679)
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AA seq |
276 aa
MALLDVCGAPRGQRPESALPVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLGGD
GERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGC
AADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKG
PGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDS
YSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ |
NT seq |
831 nt +upstreamnt +downstreamnt
atggcgctactagatgtatgcggagccccccgagggcagcggccggaatcggctctcccg
gttgcgggaagcgggcgtcgctcggacccaggacactacagtttctctatgcgatctcca
gagctcgctttaccccggggaatgcagcccacagaattcttccagtccctgggtggggac
ggagaaaggaacgttcagattgagatggcccatggcaccaccacgctcgccttcaagttc
cagcatggagtgattgcagcagtggattctcgggcctcagctgggtcctacattagtgcc
ttacgggtgaacaaggtgattgagattaacccttacctgcttggcaccatgtctggctgt
gcagcagactgtcagtactgggagcgcctgctggccaaggaatgcaggctgtactatctg
cgaaatggagaacgtatttcagtgtcggcagcctccaagctgctgtccaacatgatgtgc
cagtaccggggcatgggcctctctatgggcagtatgatctgtggctgggataagaagggt
cctggactctactacgtggatgaacatgggactcggctctcaggaaatatgttctccacg
ggtagtgggaacacttatgcctacggggtcatggacagtggctatcggcctaatcttagc
cctgaagaggcctatgaccttggccgcagggctattgcttatgccactcacagagacagc
tattctggaggcgttgtcaatatgtaccacatgaaggaagatggttgggtgaaagtagaa
agtacagatgtcagtgacctgctgcaccagtaccgggaagccaatcaataa |