KEGG   Homo sapiens (human): 5715
Entry
5715              CDS       T01001                                 

Gene name
PSMD9, Rpn4, p27
Definition
(RefSeq) proteasome 26S subunit, non-ATPase 9
  KO
K06693  26S proteasome regulatory subunit N4
Organism
hsa  Homo sapiens (human)
Pathway
hsa03050  Proteasome
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05017  Spinocerebellar ataxia
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
Network
nt06420  Ubiquitin-proteasome system
nt06460  Alzheimer disease
nt06461  Huntington disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06465  Prion disease
  Element
N01029  26S proteasome-mediated protein degradation
N01030  Mutation-caused aberrant SNCA to 26S proteasome-mediated protein degradation
N01060  Mutation-caused aberrant Abeta to 26S proteasome-mediated protein degradation
N01061  Mutation-caused aberrant Htt to 26S proteasome-mediated protein degradation
N01144  Mutation-caused aberrant SOD1 to 26S proteasome-mediated protein degradation
N01145  Mutation-inactivated VCP to 26S proteasome-mediated protein degradation
N01146  Mutation-inactivated UBQLN2 to 26S proteasome-mediated protein degradation
N01197  Scrapie conformation PrPSc to 26S proteasome-mediated protein degradation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03050 Proteasome
    5715 (PSMD9)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    5715 (PSMD9)
   05012 Parkinson disease
    5715 (PSMD9)
   05014 Amyotrophic lateral sclerosis
    5715 (PSMD9)
   05016 Huntington disease
    5715 (PSMD9)
   05017 Spinocerebellar ataxia
    5715 (PSMD9)
   05020 Prion disease
    5715 (PSMD9)
   05022 Pathways of neurodegeneration - multiple diseases
    5715 (PSMD9)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03051 Proteasome [BR:hsa03051]
    5715 (PSMD9)
Proteasome [BR:hsa03051]
 Eukaryotic proteasome
  Regulatory particles
   PA700 (19S proteasome)
    non-ATPase subunits
     5715 (PSMD9)
SSDB
Motif
Pfam: Nas2_N PDZ_6 PDZ_2 PDZ GRASP55_65
Other DBs
NCBI-GeneID: 5715
NCBI-ProteinID: NP_002804
OMIM: 603146
HGNC: 9567
Ensembl: ENSG00000110801
Vega: OTTHUMG00000168945
Pharos: O00233(Tbio)
UniProt: O00233
Position
12q24.31
AA seq 223 aa
MSDEEARQSGGSSQAGVVTVSDVQELMRRKEEIEAQIKANYDVLESQKGIGMNEPLVDCE
GYPRSDVDLYQVRTARHNIICLQNDHKAVMKQVEEALHQLHARDKEKQARDMAEAHKEAM
SRKLGQSESQGPPRAFAKVNSISPGSPASIAGLQVDDEIVEFGSVNTQNFQSLHNIGSVV
QHSEGKPLNVTVIRRGEKHQLRLVPTRWAGKGLLGCNIIPLQR
NT seq 672 nt   +upstreamnt  +downstreamnt
atgtccgacgaggaagcgaggcagagcggaggctcctcgcaggccggcgtcgtgactgtc
agcgacgtccaggagctgatgcggcgcaaggaggagatagaagcgcagatcaaggccaac
tatgacgtgctggaaagccaaaaaggcattgggatgaacgagccgctggtggactgtgag
ggctacccccggtcagacgtggacctgtaccaagtccgcaccgccaggcacaacatcata
tgcctgcagaatgatcacaaggcagtgatgaagcaggtggaggaggccctgcaccagctg
cacgctcgcgacaaggagaagcaggcccgggacatggctgaggcccacaaagaggccatg
agccgcaaactgggtcagagtgagagccagggccctccacgggccttcgccaaagtgaac
agcatcagccccggctccccagccagcatcgcgggtctgcaagtggatgatgagattgtg
gagttcggctctgtgaacacccagaacttccagtcactgcataacattggcagtgtggtg
cagcacagtgaggggaagcccctgaatgtgacagtgatccgcaggggggaaaaacaccag
cttagacttgttccaacacgctgggcaggaaaaggactgctgggctgcaacattattcct
ctgcaaagatga

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