KEGG   Homo sapiens (human): 57379Help
Entry
57379             CDS       T01001                                 

Gene name
AICDA, AID, ARP2, CDA2, HEL-S-284, HIGM2
Definition
(RefSeq) activation induced cytidine deaminase
  KO
K10989  activation-induced cytidine deaminase [EC:3.5.4.38]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04672  Intestinal immune network for IgA production
hsa05340  Primary immunodeficiency
Disease
H00086  Hyper IgM syndromes, autosomal recessive type
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04672 Intestinal immune network for IgA production
    57379 (AICDA)
 09160 Human Diseases
  09163 Immune diseases
   05340 Primary immunodeficiency
    57379 (AICDA)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.38  single-stranded DNA cytosine deaminase
     57379 (AICDA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: APOBEC2 NAD1 APOBEC_N NAD2 SNAD4 APOBEC3 APOBEC_C APOBEC4_like APOBEC4 APOBEC1 RcbX DUF2599
Motif
Other DBs
NCBI-GeneID: 57379
NCBI-ProteinID: NP_065712
OMIM: 605257
HGNC: 13203
Ensembl: ENSG00000111732
Vega: OTTHUMG00000168676
Pharos: Q9GZX7(Tbio)
UniProt: Q9GZX7 Q546Y9 Q7Z599
Position
12p13.31
AA seq 198 aa AA seqDB search
MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFGYLRNKNGCHVELL
FLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRK
AEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLSRQLRRIL
LPLYEVDDLRDAFRTLGL
NT seq 597 nt NT seq  +upstreamnt  +downstreamnt
atggacagcctcttgatgaaccggaggaagtttctttaccaattcaaaaatgtccgctgg
gctaagggtcggcgtgagacctacctgtgctacgtagtgaagaggcgtgacagtgctaca
tccttttcactggactttggttatcttcgcaataagaacggctgccacgtggaattgctc
ttcctccgctacatctcggactgggacctagaccctggccgctgctaccgcgtcacctgg
ttcacctcctggagcccctgctacgactgtgcccgacatgtggccgactttctgcgaggg
aaccccaacctcagtctgaggatcttcaccgcgcgcctctacttctgtgaggaccgcaag
gctgagcccgaggggctgcggcggctgcaccgcgccggggtgcaaatagccatcatgacc
ttcaaagattatttttactgctggaatacttttgtagaaaaccacgaaagaactttcaaa
gcctgggaagggctgcatgaaaattcagttcgtctctccagacagcttcggcgcatcctt
ttgcccctgtatgaggttgatgacttacgagacgcatttcgtactttgggactttga

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