KEGG   Homo sapiens (human): 5739Help
Entry
5739              CDS       T01001                                 

Gene name
PTGIR, IP, PRIPR
Definition
(RefSeq) prostaglandin I2 receptor
  KO
K04263  prostacyclin receptor
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
hsa04611  Platelet activation
Drug target
Beraprost (DG00160): D01551 D02720
Clinprost: D02048
Epoprostenol (DG00157): D00106 D01337
Esuberaprost (DG01839): D10628 D10703
Ibudilast: D01385
Iloprost (DG00158): D02721 D08065
Pimilprost: D01188
Ralinepag: D10725
Selexipag: D09994
Treprostinil (DG00161): D06213 D08628
Treprostinil diolamine: D10430
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    5739 (PTGIR)
 Organismal Systems
  Immune system
   04611 Platelet activation
    5739 (PTGIR)
  Circulatory system
   04270 Vascular smooth muscle contraction
    5739 (PTGIR)
G protein-coupled receptors [BR:hsa04030]
 Class A. Rhodopsin family
  Lipid
   Prostacyclin
    5739 (PTGIR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srx 7TM_GPCR_Srsx
Motif
Other DBs
NCBI-GeneID: 5739
NCBI-ProteinID: NP_000951
OMIM: 600022
HGNC: 9602
Ensembl: ENSG00000160013
Vega: OTTHUMG00000183429
Pharos: P43119(Tclin)
UniProt: P43119
Position
19q13.32
AA seq 386 aa AA seqDB search
MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATD
LLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLA
LSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPG
GAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLIL
LALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVF
QRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPL
PPTQQSSGSAVGTSSKAEASVACSLC
NT seq 1161 nt NT seq  +upstreamnt  +downstreamnt
atggcggattcgtgcaggaacctcacctacgtgcggggctcggtggggccggccaccagc
accctgatgttcgtggccggtgtggtgggcaacgggctggccctgggcatcctgagcgca
cggcgaccggcgcgcccctcggccttcgcggtgctggtgaccggactggcggccaccgac
ctgctgggcaccagcttcctgagcccggccgtgttcgtggcctatgcgcgcaacagctcc
ctgctgggcctggcccgaggcggccccgccctgtgcgatgccttcgccttcgccatgacc
ttcttcggcctggcgtccatgctcatcctctttgccatggccgtggagcgctgcctggcg
ctgagccacccctacctctacgcgcagctggacgggccccgctgcgcccgcctggcgctg
ccagccatctacgccttctgcgtcctcttctgcgcgctgcccctgctgggcctgggccaa
caccagcagtactgccccggcagctggtgcttcctccgcatgcgctgggcccagccgggc
ggcgccgccttctcgctggcctacgccggcctggtggccctgctggtggctgccatcttc
ctctgcaacggctcggtcaccctcagcctctgccgcatgtaccgccagcagaagcgccac
cagggctctctgggtccacggccgcgcaccggagaggacgaggtggaccacctgatcctg
ctggccctcatgacagtggtcatggccgtgtgctccctgcctctcacgatccgctgcttc
acccaggctgtcgcccctgacagcagcagtgagatgggggacctccttgccttccgcttc
tacgccttcaaccccatcctggacccctgggtcttcatccttttccgcaaggctgtcttc
cagcgactcaagctctgggtctgctgcctgtgcctcgggcctgcccacggagactcgcag
acacccctttcccagctcgcctcagggaggagggacccaagggccccctctgctcctgtg
ggaaaggaggggagctgcgtgcctttgtcggcttggggcgaggggcaggtggagcccttg
cctcccacacagcagtccagcggcagcgccgtgggaacgtcgtccaaagcagaagccagc
gtcgcctgctccctctgctga

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