KEGG   Homo sapiens (human): 57674Help
Entry
57674             CDS       T01001                                 

Gene name
RNF213, ALO17, C17orf27, KIAA1618, MYMY2, MYSTR, NET57
Definition
(RefSeq) ring finger protein 213
  KO
K22754  E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]
Organism
hsa  Homo sapiens (human)
Disease
H01396  Moyamoya disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    57674 (RNF213)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     57674 (RNF213)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    57674 (RNF213)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: AAA zf-C3HC4_3 zf-C3HC4 zf-C3HC4_2 AAA_22 zf-RING_2 AAA_5 AAA_7 zf-C3HC4_4 ABC_tran zf-RING_UBOX zf-RING_6 NOB1_Zn_bind
Motif
Other DBs
NCBI-GeneID: 57674
NCBI-ProteinID: NP_001243000
OMIM: 613768
HGNC: 14539
Ensembl: ENSG00000173821
Vega: OTTHUMG00000161415
Pharos: Q63HN8(Tbio)
UniProt: Q63HN8 A0A0A0MTR7
Position
17q25.3
AA seq 5207 aa AA seqDB search
MECPSCQHVSKEETPKFCSQCGERLPPAAPIADSENNNSTMASASEGEMECGQELKEEGG
PCLFPGSDSWQENPEEPCSKASWTVQESKKKKRKKKKKGNKSASSELASLPLSPASPCHL
TLLSNPWPQDTALPHSQAQQSGPTGQPSQPPGTATTPLEGDGLSAPTEVGDSPLQAQALG
EAGVATGSEAQSSPQFQDHTEGEDQDASIPSGGRGLSQEGTGPPTSAGEGHSRTEDAAQE
LLLPESKGGSSEPGTELQTTEQQAGASASMAVDAVAEPANAVKGAGKEMKEKTQRMKQPP
ATTPPFKTHCQEAETKTKDEMAAAEEKVGKNEQGEPEDLKKPEGKNRSAAAVKNEKEQKN
QEADVQEVKASTLSPGGGVTVFFHAIISLHFPFNPDLHKVFIRGGEEFGESKWDSNICEL
HYTRDLGHDRVLVEGIVCISKKHLDKYIPYKYVIYNGESFEYEFIYKHQQKKGEYVNRCL
FIKSSLLGSGDWHQYYDIVYMKPHGRLQKVMNHITDGPRKDLVKGKQIAAALMLDSTFSI
LQTWDTINLNSFFTQFEQFCFVLQQPMIYEGQAQLWTDLQYREKEVKRYLWQHLKKHVVP
LPDGKSTDFLPVDCPVRSKLKTGLIVLFVVEKIELLLEGSLDWLCHLLTSDASSPDEFHR
DLSHILGIPQSWRLYLVNLCQRCMDTRTYTWLGALPVLHCCMELAPRHKDAWRQPEDTWA
ALEGLSFSPFREQMLDTSSLLQFMREKQHLLSIDEPLFRSWFSLLPLSHLVMYMENFIEH
LGRFPAHILDCLSGIYYRLPGLEQVLNTQDVQDVQNVQNILEMLLRLLDTYRDKIPEEAL
SPSYLTVCLKLHEAICSSTKLLKFYELPALSAEIVCRMIRLLSLVDSAGQRDETGNNSVQ
TVFQGTLAATKRWLREVFTKNMLTSSGASFTYVKEIEVWRRLVEIQFPAEHGWKESLLGD
MEWRLTKEEPLSQITAYCNSCWDTKGLEDSVAKTFEKCIIEAVSSACQSQTSILQGFSYS
DLRKFGIVLSAVITKSWPRTADNFDDILKHLLTLADVKHVFRLCGTDEKILANVTEDAKR
LIAVADSVLTKVVGDLLSGTILVGQLELIIKHKNQFLDIWQLREKSLSPQDEQCAVEEAL
DWRREELLLLKKEKRCVDSLLKMCGNVKHLIQVDFGVLAVRHSQDLSSKRLNDTVTVRLS
TSSNSQRATHYHLSSQVQEMAGKIDLLRDSHIFQLFWREAAEPLSEPKEDQEAAELLSEP
EEESERHILELEEVYDYLYQPSYRKFIKLHQDLKSGEVTLAEIDVIFKDFVNKYTDLDSE
LKIMCTVDHQDQRDWIKDRVEQIKEYHHLHQAVHAAKVILQVKESLGLNGDFSVLNTLLN
FTDNFDDFRRETLDQINQELIQAKKLLQDISEARCKGLQALSLRKEFICWVREALGGINE
LKVFVDLASISAGENDIDVDRVACFHDAVQGYASLLFKLDPSVDFSAFMKHLKKLWKALD
KDQYLPRKLCDSARNLEWLKTVNESHGSVERSSLTLATAINQRGIYVIQAPKGGQKISPD
TVLHLILPESPGSHEESREYSLEEVKELLNKLMLMSGKKDRNNTEVERFSEVFCSVQRLS
QAFIDLHSAGNMLFRTWIAMAYCSPKQGVSLQMDFGLDLVTELKEGGDVTELLAALCRQM
EHFLDSWKRFVTQKRMEHFYLNFYTAEQLVYLSTELRKQPPSDAALTMLSFIKSNCTLRD
VLRASVGCGSEAARYRMRRVMEELPLMLLSEFSLVDKLRIIMEQSMRCLPAFLPDCLDLE
TLGHCLAHLAGMGGSPVERCLPRGLQVGQPNLVVCGHSEVLPAALAVYMQTPSQPLPTYD
EVLLCTPATTFEEVALLLRRCLTLGSLGHKVYSLLFADQLSYEVARQAEELFHNLCTQQH
REDYQLVMVCDGDWEHCYLPSAFSQHKVFVTPQAPLEAIQAYLAGHYRVPKQTLSAAAVF
NDRLCVGIVASERAGVGKSLYVKRLHDKMKMQLNVKNVPLKTIRLIDPQVDESRVLGALL
PFLDAQYQKVPVLFHLDVTSSVQTGIWVFLFKLLILQYLMDINGKMWLRNPCHLYIVEIL
ERRTSVPSRSSSALRTRVPQFSFLDIFPKVTCRPPKEVIDMELSALRSDTEPGMDLWEFC
SETFQRPYQYLRRFNQNQDLDTFQYQEGSVEGTPEECLQHFLFHCGVINPSWSELRNFAR
FLNYQLRDCEASLFCNPSFIGDTLRGFKKFVVTFMIFMARDFATPSLHTSDQSPGKHMVT
MDGVREEDLAPFSLRKRWESEPHPYVFFNDDHTTMTFIGFHLQPNINGSVDAISHLTGKV
IKRDVMTRDLYQGLLLQRVPFNVDFDKLPRHKKLERLCLTLGIPQATDPDKTYELTTDNM
LKILAIEMRFRCGIPVIIMGETGCGKTRLIKFLSDLRRGGTNADTIKLVKVHGGTTADMI
YSRVREAENVAFANKDQHQLDTILFFDEANTTEAISCIKEVLCDHMVDGQPLAEDSGLHI
IAACNPYRKHSEEMICRLESAGLGYRVSMEETADRLGSIPLRQLVYRVHALPPSLIPLVW
DFGQLSDVAEKLYIQQIVQRLVESISLDENGTRVITEVLCASQGFMRKTEDECSFVSLRD
VERCVKVFRWFHEHSAMLLAQLNAFLSKSSVSKNHTERDPVLWSLMLAIGVCYHASLEKK
DSYRKAIARFFPKPYDDSRLLLDEITRAQDLFLDGVPLRKTIAKNLALKENVFMMVVCIE
LKIPLFLVGKPGSSKSLAKTIVADAMQGPAAYSDLFRSLKQVHLVSFQCSPHSTPQGIIS
TFRQCARFQQGKDLQQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIEDDPAPHKKVG
FVGISNWALDPAKMNRGIFVSRGSPNETELIESAKGICSSDILVQDRVQGYFASFAKAYE
TVCKRQDKEFFGLRDYYSLIKMVFAAAKASNRKPSPQDIAQAVLRNFSGKDDIQALDIFL
ANLPEAKCSEEVSPMQLIKQNIFGPSQKVPGGEQEDAESRYLLVLTKNYVALQILQQTFF
EGDQQPEIIFGSGFPKDQEYTQLCRNINRVKICMETGKMVLLLNLQNLYESLYDALNQYY
VHLGGQKYVDLGLGTHRVKCRVHPNFRLIVIEEKDVVYKHFPIPLINRLEKHYLDINTVL
EKWQKSIVEELCAWVEKFINVKAHHFQKRHKYSPSDVFIGYHSDACASVVLQVIERQGPR
ALTEELHQKVSEEAKSILLNCATPDAVVRLSAYSLGGFAAEWLSQEYFHRQRHNSFADFL
QAHLHTADLERHAIFTEITTFSRLLTSHDCEILESEVTGRAPKPTLLWLQQFDTEYSFLK
EVRNCLTNTAKCKILIFQTDFEDGIRSAQLIASAKYSVINEINKIRENEDRIFVYFITKL
SRVGRGTAYVGFHGGLWQSVHIDDLRRSTLMVSDVTRLQHVTISQLFAPGDLPELGLEHR
AEDGHEEAMETEASTSGEVAEVAEEAMETESSEKVGKETSELGGSDVSILDTTRLLRSCV
QSAVGMLRDQNESCTRNMRRVVLLLGLLNEDDACHASFLRVSKMRLSVFLKKQEESQFHP
LEWLAREACNQDALQEAGTFRHTLWKRVQGAVTPLLASMISFIDRDGNLELLTRPDTPPW
ARDLWMFIFSDTMLLNIPLVMNNERHKGEMAYIVVQNHMNLSENASNNVPFSWKIKDYLE
ELWVQAQYITDAEGLPKKFVDIFQQTPLGRFLAQLHGEPQQELLQCYLKDFILLTMRVST
EEELKFLQMALWSCTRKLKAASEAPEEEVSLPWVHLAYQRFRSRLQNFSRILTIYPQVLH
SLMEARWNHELAGCEMTLDAFAAMACTEMLTRNTLKPSPQAWLQLVKNLSMPLELICSDE
HMQGSGSLAQAVIREVRAQWSRIFSTALFVEHVLLGTESRVPELQGLVTEHVFLLDKCLR
ENSDVKTHGPFEAVMRTLCECKETASKTLSRFGIQPCSICLGDAKDPVCLPCDHVHCLRC
LRAWFASEQMICPYCLTALPDEFSPAVSQAHREAIEKHARFRQMCNSFFVDLVSTICFKD
NAPPEKEVIESLLSLLFVQKGRLRDAAQRHCEHTKSLSPFNDVVDKTPVIRSVILKLLLK
YSFHDVKDYIQEYLTLLKKKAFITEDKTELYMLFINCLEDSILEKTSAYSRNDELNHLEE
EGRFLKAYSPASRGREPANEASVEYLQEVARIRLCLDRAADFLSEPEGGPEMAKEKQCYL
QQVKQFCIRVENDWHRVYLVRKLSSQRGMEFVQGLSKPGRPHQWVFPKDVVKQQGLRQDH
PGQMDRYLVYGDEYKALRDAVAKAVLECKPLGIKTALKACKTPQSQQSAYFLLTLFREVA
ILYRSHNASLHPTPEQCEAVSKFIGECKILSPPDISRFATSLVDNSVPLLRAGPSDSNLD
GTVTEMAIHAAAVLLCGQNELLEPLKNLAFSPATMAHAFLPTMPEDLLAQARRWKGLERV
HWYTCPNGHPCSVGECGRPMEQSICIDCHAPIGGIDHKPRDGFHLVKDKADRTQTGHVLG
NPQRRDVVTCDRGLPPVVFLLIRLLTHLALLLGASQSSQALINIIKPPVRDPKGFLQQHI
LKDLEQLAKMLGHSADETIGVVHLVLRRLLQEQHQLSSRRLLNFDTELSTKEMRNNWEKE
IAAVISPELEHLDKTLPTMNNLISQDKRISSNPVAKIIYGDPVTFLPHLPRKSVVHCSKI
WSCRKRITVEYLQHIVEQKNGKERVPILWHFLQKEAELRLVKFLPEILALQRDLVKQFQN
VQQVEYSSIRGFLSKHSSDGLRQLLHNRITVFLSTWNKLRRSLETNGEINLPKDYCSTDL
DLDTEFEILLPRRRGLGLCATALVSYLIRLHNEIVYAVEKLSKENNSYSVDAAEVTELHV
ISYEVERDLTPLILSNCQYQVEEGRETVQEFDLEKIQRQIVSRFLQGKPRLSLKGIPTLV
YRHDWNYEHLFMDIKNKMAQDSLPSSVISAISGQLQSYSDACEVLSVVEVTLGFLSTAGG
DPNMQLNVYTQDILQMGDQTIHVLKALNRCQLKHTIALWQFLSAHKSEQLLRLHKEPFGE
ISSRYKADLSPENAKLLSTFLNQTGLDAFLLELHEMIILKLKNPQTQTEERFRPQWSLRD
TLVSYMQTKESEILPEMASQFPEEILLASCVSVWKTAAVLKWNREMR
NT seq 15624 nt NT seq  +upstreamnt  +downstreamnt
atggagtgtccttcgtgccagcatgtctccaaggaggaaacccccaagttctgcagccag
tgcggagagaggctgcctcctgcagcccccatagcagattctgagaacaataactccaca
atggcgtcggcctcggagggtgaaatggagtgtgggcaggagctgaaggaggaagggggc
ccgtgcttgttcccgggctcagacagttggcaagaaaaccccgaggagccctgttccaaa
gcctcctggaccgtccaagaaagcaaaaagaagaaaaggaagaagaaaaagaaggggaac
aagtccgcttcctcagagctggcttccttgcccctttctcctgccagcccctgtcacctg
actttgctttcaaacccgtggcctcaggacacagccctgccccacagccaagcccagcag
agtggccccactggccagccgagccagcccccaggcacagccaccacgccactggagggt
gacggcctctccgcgcccaccgaggttggcgacagccccctgcaggcccaggctttggga
gaggcaggagtggccacaggaagtgaggctcagagcagcccgcaattccaggaccacacg
gaaggggaggaccaggacgcttccatcccctctgggggcagaggcctgtcccaggagggg
accggtccccccacctctgctggtgaaggccattctaggactgaagatgctgcccaggag
ctcctgttgcctgagtcaaaaggaggcagctctgagcccgggacagaactgcagaccacc
gagcaacaggcaggggcctcagcctctatggcagttgatgctgtagctgagccagccaat
gcagttaaaggggccgggaaggaaatgaaagagaagacccagagaatgaaacagccacca
gcaaccactcctcctttcaaaacacactgccaggaagctgagaccaagaccaaggacgag
atggctgctgctgaagaaaaagtcggtaagaatgaacaaggggagcctgaagacctcaag
aagccagaggggaagaacagaagtgcagctgctgtgaaaaacgagaaggagcaaaaaaac
caggaagcagatgtccaggaagtgaaggcaagcacgctgagcccgggtggaggagtcacc
gtgttcttccacgccatcatctctcttcatttcccattcaatcctgacctccataaagtc
ttcatcagaggaggagaagaatttggggagtcaaaatgggacagcaatatctgtgagctg
cactacaccagagacttgggtcatgaccgcgttcttgttgaaggcattgtctgcatttcc
aagaagcacctagataaatacattccttacaagtacgtcatttataatggggaatctttt
gagtatgagttcatttacaagcaccagcagaagaagggcgagtacgtcaaccgctgtctg
ttcataaaatcttcacttctgggctcaggagactggcatcagtactatgacatagtttat
atgaagcctcatgggagactccagaaagtcatgaaccacatcacagacgggccgaggaag
gacctggtgaaggggaagcagattgccgctgcgctcatgctggacagcaccttcagcatc
ctgcagacctgggacaccatcaacctgaacagcttcttcacccagttcgagcagttttgc
tttgtcctgcaacagcctatgatttatgaaggacaggcacagctgtggaccgatttgcag
tacagggagaaagaggtgaagagatacctgtggcaacatctgaaaaaacacgtggtacca
ttgccggacggaaaaagcacggactttttgcctgtggactgcccagtgaggagtaaactg
aaaacaggcctgattgtcctttttgtagtggaaaaaattgagcttttattagaaggcagc
ctggactggttgtgtcacctcctaacctcagatgccagctcaccagatgagtttcaccgt
gacctaagccacatccttgggatacctcagagctggcggctgtacctggtgaacctgtgc
caaagatgcatggacacaaggacgtacacctggctgggcgccctgcctgtcctgcactgc
tgtatggagctggccccgcggcacaaggatgcctggagacagcctgaggacacctgggcc
gctctggagggactctccttctcaccgttccgggaacaaatgctagatacgagttcccta
cttcagtttatgagagagaagcagcatttgctgagcatagacgagcctctcttccggtcc
tggtttagtctgctacctctgagtcacctggttatgtatatggaaaacttcattgagcac
ctgggtcgttttcctgctcatatcctggactgtctttcagggatttactaccggcttccg
ggacttgagcaagtcttgaatacgcaggatgttcaggatgttcagaacgttcagaacatt
ttagaaatgctgttgcgactcctggacacttaccgggacaagattcccgaggaggccttg
tcaccatcctacctgactgtgtgtctgaaactgcatgaagccatctgcagcagcacaaag
ctacttaagttttacgagctgccagccttatctgccgagattgtctgcagaatgattaga
cttctatctctggtggattctgcaggacagagagatgaaactggaaataattcagtccaa
acagtcttccaagggacccttgctgctacgaaaaggtggctccgagaagtttttacaaag
aacatgctcacatcttcaggtgcctcattcacatacgtcaaggaaattgaggtctggagg
cggctggtggaaatccaattccccgcggagcatggctggaaggagtcgttgctgggagac
atggaatggaggctcacaaaggaggaacccctctcccagatcactgcctactgcaatagt
tgctgggacaccaaaggcttagaggacagtgtggccaagaccttcgagaaatgcatcatt
gaagccgtgagctcagcctgccagtctcagaccagtatccttcaggggttctcttactct
gatttgcggaaatttggcatcgtcttgtctgctgtgatcactaagtcctggcctaggacc
gcggacaacttcgatgacattttaaagcatctgctcacgttggcagatgtcaagcacgtc
ttcagattgtgtggaaccgacgagaaaatactagcaaatgtcacagaggatgccaagagg
ctgatagctgttgccgactctgtgttgacgaaagttgttggtgacctcctaagtggcacg
attttagttggacaactggagctgattataaagcacaagaatcagtttcttgacatctgg
caactgagggaaaaaagtctttcaccccaggatgaacaatgtgctgtggaggaagcactg
gattggagaagggaggaactgttacttctaaagaaagagaaaagatgtgttgatagtctc
ctgaagatgtgtgggaacgtgaaacatctgatacaagtggactttggagtgcttgcagta
agacactcacaagacctcagcagtaaaagattaaatgacaccgtgacagtgagactgtcc
acctcctcgaactcgcagagggcaacgcattaccacctgagctcccaggtccaagaaatg
gctgggaagatagacttgctcagagacagccacatcttccagctcttctggcgggaagcc
gcagagccgctgagtgagcctaaggaggaccaggaagccgcagagttgctgagtgagccc
gaagaagaatcagaaaggcacatccttgagcttgaagaggtgtatgactatttgtatcag
ccttcttacagaaagttcattaagttgcaccaggatctaaagtcaggagaggtcaccctt
gcagagattgatgtcatcttcaaggactttgtgaataaatacacggacctggattcagaa
cttaagatcatgtgcaccgtggaccaccaggaccaaagagattggatcaaggaccgagtc
gaacagatcaaggaataccatcacctgcaccaggctgtccacgcagccaaggtcatcttg
caggtcaaagagagcctgggactgaacggtgacttcagtgttctcaacactttactaaat
tttactgataacttcgacgactttcgccgtgaaacactggaccagatcaaccaggagctc
atccaggccaaaaagctgctccaggacatcagcgaggcccggtgcaaggggctgcaggct
ctgtccctgagaaaggagttcatctgctgggtccgggaggctcttggaggcatcaatgag
ctgaaggtgtttgtggacctggcctccatctcagcgggggagaatgacattgatgtggac
cgggtggcctgcttccatgacgctgtgcagggctacgcatccctgctatttaagctggac
cccagcgtggacttcagtgcattcatgaagcatctgaaaaagctgtggaaggctctggat
aaggaccagtacctgcccaggaaactgtgtgactccgccaggaacttggaatggctgaag
actgtgaatgagagtcatgggtctgtggaacgctcatccctgaccctggccacggccatc
aaccaaagaggcatctatgtgatccaggcgcccaaaggtggccaaaagatttccccagac
acggttctgcacttgatccttcctgagagccctggcagccacgaggagtcacgagagtac
tctttagaggaggtgaaggagcttttgaacaagttgatgctgatgtctggcaagaaggat
cgtaacaacacggaagtggagaggttttcagaggtcttctgcagtgtgcagaggctcagc
caggccttcatcgacctgcactctgctgggaatatgctgttcaggacgtggatcgccatg
gcctactgctcccccaagcagggtgtgtccctccaaatggactttggcttggacctggtg
acggagcttaaagaaggtggagatgtcactgagctgctggcagccctctgcaggcagatg
gagcacttccttgacagctggaagagatttgtgacccagaagcgaatggagcacttttac
ctgaacttctacacggcagagcagctggtttacctgagcactgagctcaggaagcagccc
ccgagtgatgccgccctaacgatgctatccttcatcaaaagcaactgcaccctgagggat
gtcttaagggcctctgtggggtgtgggagtgaggccgccaggtaccgcatgaggagagtc
atggaagagctcccgctgatgctcttatcagagttcagcctggtggacaagctgaggatc
atcatggagcagtccatgaggtgccttcctgccttcctgcccgactgcctcgacctagag
acccttggccactgtctggctcacctggcagggatgggtgggtctcccgtggagcgttgt
ctcccgagaggtctgcaggtcggccagcccaacctcgtcgtctgtggccactccgaggtg
ttgccagccgccctggctgtctacatgcaaaccccaagccagcccctgcccacttacgat
gaggtgctgctctgcaccccggcaaccacctttgaggaggtggcactgttgctgcgccgc
tgcctgaccctgggctccctggggcacaaggtctacagcctgctgttcgcagatcagctg
agctacgaggtggcacgccaagcggaggagcttttccacaatctgtgcacgcagcagcac
cgagaagactaccagctcgtcatggtctgtgatggggactgggagcactgctacctcccc
tctgccttcagccagcacaaggtcttcgtcaccccccaggcacccctcgaggccatccaa
gcctacctggcaggtcactaccgggtcccgaagcagaccctgtcggcggcagccgtgttc
aatgaccggctgtgtgttgggatcgtggcctcggagcgagcaggtgttggaaagtctctg
tacgtgaagaggttgcacgacaaaatgaagatgcagttaaacgtgaaaaatgtgcctctg
aaaacaattcgactgatcgaccctcaggtggatgagagccgagtcctgggcgccctgctg
cccttcctggatgcgcagtatcagaaggtccccgtgctctttcacctggacgtgacctcc
tcagtgcagactggaatttgggtgtttcttttcaagctcctcattttacaatacttaatg
gatataaatgggaaaatgtggcttcggaacccctgccatttgtatatcgttgaaatcctg
gaaaggaggacgtcagtgccgtcgaggagctcttcagcgctgcgtacacgtgtaccccag
ttcagttttcttgacatcttcccaaaagtcacctgcaggcctcccaaagaggtgatagac
atggagctgagtgccctgaggagtgacacagagcctgggatggatctgtgggagttctgc
agcgaaactttccaaagaccttaccagtatttaagacgattcaatcaaaaccaagaccta
gacacgtttcagtatcaagaaggctctgtcgaaggcaccccggaggaatgcctccagcat
ttcctgtttcactgcggggtaataaacccatcctggtcagagcttcggaactttgctcgg
ttcctgaattatcagctcagagattgtgaggcctctctcttctgcaatccgagttttatt
ggcgacacactgaggggcttcaagaagttcgtggtgaccttcatgatctttatggcaaga
gattttgccacaccatcactccacacctctgaccaaagcccggggaagcacatggtcacc
atggatggggttagggaagaagatctagcgcccttctccctccggaagaggtgggagtcg
gagcctcacccatacgttttcttcaatgacgaccacacaaccatgacattcatcggcttc
catctgcagcccaacatcaacggcagtgtcgatgccatcagtcacttgactgggaaggtc
atcaagagagacgtcatgaccagggacctgtaccagggcctgctgctccagagggtgccc
ttcaatgtcgactttgataaactgcccagacacaagaaacttgagaggctctgcctgacc
ttagggatcccccaggccaccgaccccgacaaaacgtatgagctcacaaccgacaatatg
cttaaaatccttgccatcgagatgcggttccggtgtgggatcccggttatcatcatggga
gaaactggctgtgggaaaaccaggcttattaaattccttagcgacctgcggcgtggtggt
accaatgctgacaccataaagctggtcaaggtgcacggaggaacaactgcagacatgatc
tactccagagtcagggaggctgaaaatgtggccttcgccaataaggaccaacatcagttg
gacaccatcttgttttttgatgaagccaacacaacggaagctataagctgtatcaaagaa
gtcctgtgtgatcatatggtggatggccagcctctggctgaggactctggcctgcatatt
atagctgcctgcaatccataccggaagcactctgaggagatgatctgccgtttggagtca
gctggtttgggctacagggttagtatggaggagacggccgacaggctgggctccattcct
ctgaggcagctggtataccgggtccatgctctgcccccgagcctgattcctctggtgtgg
gactttggacaactgagtgacgttgctgaaaagctctacatccagcagattgtccagaga
ctggttgagtccatcagcctagatgaaaacgggactcgcgtgatcacagaagtcctctgc
gcctctcagggtttcatgaggaaaacagaagatgagtgcagctttgtcagcctcagggac
gtggagcgctgtgtgaaagttttcaggtggttccacgagcacagcgcgatgctcttagcg
cagctgaatgcctttctctccaagtccagcgtcagcaaaaatcacaccgagagagatccc
gtcctctggtcgttgatgctggccatcggggtgtgttaccatgcctctttagaaaagaaa
gactcatatcggaaagccatcgccaggttctttccgaaaccgtatgacgacagcaggctg
cttctggatgaaataacacgggcacaggatctttttctggacggcgtacctctgaggaaa
accatcgccaagaacttggccttgaaggagaacgtcttcatgatggtcgtctgcatcgag
ctgaagattcccctcttcctggtggggaagcccggcagctccaagtctctcgccaagacc
atcgtggcagacgccatgcagggcccggctgcctactcagatctcttccgcagcctgaag
caggtccacctggtgtccttccagtgcagcccgcactccaccccacagggcatcatcagc
accttccggcagtgcgcccgctttcagcaggggaaggacctgcagcagtacgtctctgtg
gtggtgttagatgaggtggggctggcggaagactcacccaaaatgcccctgaagactctg
cacccgctgctggaagacggatgcattgaagacgatcccgccccccacaaaaaggtcggc
ttcgtgggcatctccaactgggcccttgaccctgccaagatgaaccggggcatttttgtg
tcacgtggcagccccaacgagacagagctcatagagagcgccaagggcatctgctcctca
gacatcctcgtccaggaccgagtccaagggtactttgcgtcctttgccaaagcctacgaa
acggtgtgtaagcgccaggacaaggaattcttcgggcttcgtgactactacagcctcatc
aaaatggtctttgctgcagcaaaggcttcaaatagaaagccttccccgcaagacattgca
caggctgtccttaggaacttcagtggcaaggatgacatccaagctttggacatctttctg
gccaatttgcccgaggccaagtgctcagaggaagtcagccccatgcagctgatcaaacag
aacatctttgggccttctcagaaggtgccgggtggagagcaggaagatgctgagtcccgc
tacttactcgtgctgaccaaaaactacgtggcactgcagatcctgcagcagacattcttc
gagggggaccagcagccggagattatttttggttctggtttccccaaggaccaagagtac
acccagctctgcagaaacatcaatcgtgtgaagatctgcatggaaacaggcaagatggtg
ttgcttctcaacctgcagaacctctacgagagcctctacgacgcactcaaccagtactac
gtccacctcggcggccagaagtacgtggacctcggtctggggacccaccgcgtcaaatgt
cgggttcaccccaacttccgcctgattgtcattgaagagaaagacgtcgtgtacaaacac
tttcccatccccctcattaaccggctggagaagcactatctggatatcaacacggtgctg
gagaaatggcagaagagcatcgtggaggagctctgtgcgtgggtggagaagttcatcaat
gtcaaagcacatcatttccagaagaggcacaaatacagcccctctgacgtcttcatcggc
taccactcggacgcctgcgcgtctgtggtgctgcaggtcatagagaggcagggtccccgg
gccttgacggaggaacttcaccagaaggtgtctgaggaggccaaatcgatcctgctgaac
tgcgctacgcccgatgccgtggtccggctgagcgcctactcgctgggcgggttcgcagcg
gagtggctgtcgcaggagtactttcacagacagaggcacaactcctttgcagatttcctt
caggcacacctgcacacggcagacctggagcgccacgccatcttcacagagatcaccact
ttctccaggctgctaacaagtcacgactgtgaaattttagaatcagaggtcacaggcagg
gctccgaaacccacactcctgtggctgcagcagtttgacaccgagtactcattcctcaaa
gaagtccgaaactgtttaacgaatacagccaaatgtaaaatcctcatttttcagacagat
tttgaagatggaatccgtagcgcccagctcattgcctcagctaagtattctgttataaat
gaaatcaacaaaatacgagaaaatgaggaccgtatcttcgtctatttcatcacaaaactg
tcccgggtgggaagaggaacagcctatgtgggcttccacggagggctgtggcagtctgtc
cacatcgatgacctccggagatccaccctcatggtttctgatgtgaccaggctgcagcat
gtcaccatcagccagctgttcgcgcccggagacttgcctgagctgggcttggaacaccgg
gcggaagacggccatgaggaggcgatggagacggaggccagcacatcaggggaggtggca
gaggtggcagaggaggccatggaaacagaaagttctgagaaggtgggaaaggaaacctct
gaactcggaggcagtgatgtgtcgatcctggacaccaccaggctgctgagaagctgtgtg
cagagcgccgtgggcatgctcagagaccagaacgagagctgcacgcgcaatatgcggagg
gtggtgctcctcctgggcctcttgaatgaggatgacgcgtgccacgcctctttcttgcgg
gtatccaagatgcgcctcagtgtctttttaaagaagcaagaagagagccagtttcaccct
ctggagtggttggcaagggaagcctgcaaccaggacgctctccaggaggcgggcacattc
aggcacaccctctggaagcgggtccaaggtgctgtcacccctctgctggcgagcatgata
tcattcatcgacagagacggcaacctagagttactgaccaggccagatactccgccctgg
gcaagagatctttggatgtttattttcagtgacacgatgcttctgaacattcctcttgtg
atgaataatgaaagacataaaggtgagatggcctacatcgtggtgcagaaccacatgaac
ctttccgagaacgcttccaacaacgtccctttcagctggaaaatcaaggactatctggag
gagctgtgggtccaggctcagtacatcacagacgcagaaggactgcccaagaagttcgtg
gacatctttcagcagactcctctgggcaggtttcttgcccagctccatggagagccgcag
caggaacttcttcagtgttacttgaaggatttcattctcttgaccatgcgtgtgtcaacg
gaggaggaattaaagtttctgcagatggctctgtggtcctgcactaggaaactgaaagcg
gcgtcagaagcgcccgaggaagaggtttccttaccgtgggtgcaccttgcctaccagcgt
ttcagaagccgtctgcagaacttttccagaatcctgaccatctaccctcaggttctccac
agcctgatggaagcccgttggaaccatgagctggctggatgtgagatgaccctggacgca
tttgccgcaatggcctgcacggagatgctgacaagaaacaccctgaagcccagtccccag
gcgtggctacagttggtgaagaatctttccatgccgctggagctcatctgctccgatgag
cacatgcaaggcagcgggagcctggcccaggctgtcatcagggaagtcagagcccagtgg
agtcggattttctccaccgcactcttcgtggagcacgtgctcctaggaaccgagagccgc
gtccccgagttacaggggctggtgaccgagcacgtcttcttactagacaagtgtcttcga
gagaactctgacgtgaagacgcacgggccttttgaggccgtgatgcgcactctctgtgaa
tgcaaggagacagccagcaagaccctcagcaggtttgggattcagccgtgctccatctgc
ctgggagatgcaaaggaccccgtctgtctgccctgcgaccacgtgcactgcctgcgctgc
ctcagggcctggtttgcctcagagcagatgatatgcccctactgtttaactgccttgcca
gacgaattctctccagctgtttcccaagcgcacagggaagccattgaaaagcatgcccgc
ttccggcagatgtgcaacagtttcttcgtagacctggtgtccaccatttgcttcaaggac
aacgctccgcctgagaaggaagtgattgagagcctgctctctctcctcttcgtccaaaag
gggcgcttaagagatgctgcccagagacactgtgaacacacaaaatctctctctccattc
aatgatgttgtggataagactcctgtcatccgctcagtgatactgaaactgcttttgaag
tacagctttcatgatgtaaaagattatattcaggaatatttgaccctgttaaaaaagaaa
gcattcataactgaagataaaactgaactgtacatgctcttcatcaactgcctggaggat
tcaatacttgagaagaccagtgcttactccagaaatgatgaactgaaccacctagaagag
gaaggtcgtttccttaaggcatattctccagcaagccggggccgagagcctgccaacgag
gcctcggttgaatacctgcaagaggtggcccggatccgcctctgcctcgacagagctgca
gatttcctctcggagcctgagggaggcccagagatggccaaggagaagcagtgctacctg
cagcaagtcaagcagttctgtatccgggtggagaacgactggcaccgggtgtacctggtg
cggaagctcagcagccagcgggggatggagttcgtgcagggcctctccaagcccggccgc
ccgcaccagtgggtgtttcccaaggacgttgtcaagcagcaggggctgcggcaggaccac
ccaggccagatggataggtacctggtgtacggcgatgaatacaaggctctccgtgatgct
gtggccaaagctgtcctcgagtgcaagccactgggcattaagactgctctgaaggcctgc
aagaccccccaaagccagcagtcagcctacttcctgttaacactgtttagagaggtggct
attttgtacagatcccacaatgcaagcctccaccccacgccagagcaatgtgaagctgtg
agcaaattcattggcgaatgcaagatcctttcacctcctgatatcagccgttttgcaaca
tcgctcgtggacaattctgtgccattgttgagggcggggcctagtgacagcaaccttgat
ggaacggtgacagaaatggccattcatgctgcagccgtccttctgtgtggacagaatgaa
ctcttggagcccctaaagaatctggccttctccccagccaccatggcgcatgcttttctt
ccaaccatgcctgaagacttgctggctcaagctcggaggtggaagggtctggagcgagtc
cactggtacacttgtcccaacggccatccttgctccgtgggagagtgtggcaggccgatg
gaacagagcatctgcattgactgccatgcgccgattggaggcattgaccacaaacctcgg
gacggctttcatctggtcaaagacaaggcagacagaacgcagaccggccacgtgctgggc
aacccgcagcggagagacgtggtgacatgtgaccgagggctgcccccagtggtcttcctc
cttatccggctactcactcacttggctctgcttctgggagcgtcccagagttcccaggct
ctgataaacatcattaagcctccagtgagggatccaaaaggctttctgcagcagcacatc
ctgaaggacctggagcagttggccaagatgctgggacacagtgccgacgagaccatcggc
gtggtccacctcgtcctgcgcaggcttctccaagagcagcaccagctctctagcagaagg
cttttaaattttgacacagaattgtcaactaaagaaatgaggaacaactgggaaaaggaa
atcgcagctgtgatttctcctgaactggagcatctagataaaacccttcccaccatgaat
aatctcatcagccaagataagcgtatcagctctaaccctgtggccaaaataatatatggt
gacccagtgaccttcctgccccacctgccccggaaaagtgtggtccattgctctaagatt
tggagctgcaggaaaagaattacagttgagtacctccagcacattgtggaacagaaaaat
ggcaaagaaagagtgcccatcctctggcatttcctgcagaaggaagcagagctgaggctg
gtaaagttcctgcctgagattttggccttgcaaagggatctagtgaagcagttccagaac
gtccagcaagttgaatacagctccatcagaggcttcctcagcaagcacagctcagatggg
ttgaggcagctgcttcacaacaggatcacagtctttctgtccacatggaacaaactgagg
agatcgcttgagacgaacggtgagatcaacctacccaaagactactgcagcactgacttg
gatctggacactgagtttgagatcctcttgccacgccgacggggcctgggcctctgtgct
accgctctcgtcagctacttgattcgcctacacaatgaaattgtctacgccgtggaaaaa
ctctccaaggaaaacaacagctattccgtggatgccgccgaggtcactgaactgcatgtc
atcagttatgaagtggagcgggacctgactccactgattctctccaactgccagtaccag
gtggaggagggcagagagaccgtgcaggagttcgatctggagaagattcagcggcagatc
gtcagccgcttcctccagggcaagccccggctgagcctcaagggaatacccactctggtg
tacagacacgactggaactatgaacatctctttatggacatcaagaacaaaatggcacag
gactccctccccagctcggtcattagtgccatcagtggacagctgcagtcctacagcgat
gcctgtgaagtgctgtctgtcgtagaagtcactctggggtttctgagcacagctggtggg
gatccaaacatgcagctgaatgtgtatactcaagacatcctgcaaatgggtgatcagacg
attcacgtgttaaaggccttaaacagatgccagttaaaacacaccattgccctctggcag
ttcctgtctgctcataagtctgaacagctgctgcggctgcacaaagagccatttggggaa
atcagttcaaggtacaaagcggatctgagcccggaaaatgctaagctcctcagcacattc
ctaaatcagactggcctagacgccttcctgctagagctgcacgaaatgataatcttgaaa
ctaaagaacccccaaacccaaaccgaggagcgcttccgccctcagtggagcctgagagac
actctcgtaagttacatgcaaactaaagaaagtgaaattcttcctgaaatggcatctcag
ttcccagaagagatactgctcgccagctgtgtctcagtgtggaaaacagctgctgtgctg
aaatggaatcgagaaatgagatag

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