KEGG   Homo sapiens (human): 5787
Entry
5787              CDS       T01001                                 
Symbol
PTPRB, HPTP-BETA, HPTPB, PTPB, R-PTP-BETA, VEPTP
Name
(RefSeq) protein tyrosine phosphatase receptor type B
  KO
K05694  receptor-type tyrosine-protein phosphatase beta [EC:3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04520  Adherens junction
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    5787 (PTPRB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5787 (PTPRB)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     5787 (PTPRB)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Receptor PTPs
    5787 (PTPRB)
SSDB
Motif
Pfam: fn3 Y_phosphatase Ig_ILCR1 FN3_Tor_3rd Fn3_Dep-1_4th PTP_tm Tc-R-P PTP-SAK PTP-NADK DSPc Fn3_ELFN Y_phosphatase3 Glyco_hydro_66 PTPlike_phytase CR_prot_dom_plant
Other DBs
NCBI-GeneID: 5787
NCBI-ProteinID: NP_002828
OMIM: 176882
HGNC: 9665
Ensembl: ENSG00000127329
UniProt: P23467
Structure
Position
12:complement(70515870..70637429)
AA seq 1997 aa
MLSHGAGLALWITLSLLQTGLAEPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSS
DTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERTVVLQTDPLPPARFGVSK
EKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYN
IAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKG
ILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTND
GSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSC
VSGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLL
NITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVPLAVLQLRVKHANE
TSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISG
DLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNES
ISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDYL
SVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYE
NHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPK
SENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWS
GANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAF
IEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFE
HTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAA
GVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTE
GRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFS
FQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGD
FDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTA
PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVY
GLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDS
DFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDS
TITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDE
LKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIKLGAEMESLGGKCD
PTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGAI
EGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTS
CPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYD
ATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVM
VTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLI
RHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRI
LQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPI
YENVNPEYHRDPVYSRH
NT seq 5994 nt   +upstreamnt  +downstreamnt
atgctgagccatggagccgggttggccttgtggatcacactgagcctgctgcagactgga
ctggcggagccagagagatgtaacttcaccctggcggagtccaaggcctccagccattct
gtgtctatccagtggagaattttgggctcaccctgtaactttagcctcatctatagcagt
gacaccctgggggccgcgttgtgccctacctttcggatagacaacaccacatacggatgt
aaccttcaagatttacaagcaggaaccatctataacttcaggattatttctctggatgaa
gagagaacagtggtcttgcaaacagatcctttacctcctgctaggtttggagtcagtaaa
gagaagacgacttcaaccagcttgcatgtttggtggactccttcttccggaaaagtcacc
tcatatgaggtgcaattatttgatgaaaataaccaaaagatacagggggttcaaattcaa
gaaagtacttcatggaatgaatacacttttttcaatctcactgctggtagtaaatacaat
attgccatcacagctgtttctggaggaaaacgttctttttcagtttataccaatggatca
acagtgccatctccagtgaaagatattggtatttccacaaaagccaattctctcctgatt
tcctggtcccatggttctgggaatgtggaacgataccggctgatgctaatggataaaggg
atcctagttcatggcggtgttgtggacaaacatgctacttcctatgcttttcacgggctg
acccctggctacctctacaacctcactgttatgactgaggctgcagggctgcaaaactac
aggtggaaactagtcaggacagcccccatggaagtctcaaatctgaaggtgacaaatgat
ggcagtttgacctctctaaaagtcaaatggcaaagacctcctggaaatgtggattcttac
aatatcaccctgtctcacaaagggaccatcaaggaatccagagtattagcaccttggatt
actgaaactcactttaaagagttagtccccggtcgactttatcaagttactgtcagctgt
gtctctggtgaactgtctgctcagaagatggcagtgggcagaacatttccagacaaagtt
gcaaacctggaggcaaacaataatggcaggatgaggtctcttgtagtgagctggtcgccc
cctgctggagactgggagcagtatcggatcctactcttcaatgattctgtggtgctgctc
aacatcactgtgggaaaggaagaaacacagtatgtcatggatgacacggggctcgtaccg
ggaagacagtatgaggtggaagtcattgttgagagtggaaatttgaagaattctgagcgt
tgccaaggcaggacagtccccctggctgtcctccagcttcgtgtcaaacatgccaatgaa
acctcactgagtatcatgtggcagacccctgtagcagaatgggagaaatacatcatttcc
ctagctgacagagacctcttactgatccacaagtcactctccaaagatgccaaagaattc
acttttactgacctggtgcctggacgaaaatacatggctacagtcaccagtattagtgga
gacttaaaaaattcctcttcagtaaaaggaagaacagtgcctgcccaagtgactgacttg
catgtggccaaccaaggaatgaccagtagtctgtttactaactggacccaggcacaagga
gacgtagaattttaccaagtcttactgatccatgaaaatgtggtcattaaaaatgaaagc
atctccagtgagaccagcagatacagcttccactctctcaagtccggcagcctgtactcc
gtggtggtaacaacagtgagtggagggatctcttcccgacaagtggttgtggagggaaga
acagtcccttccagtgtgagtggagtaacggtgaacaattccggtcgtaatgactacctc
agcgtttcctggctgctggcgcccggagatgtggataactatgaggtaacattgtctcat
gacggcaaggtggttcagtcccttgtcattgccaagtctgtcagagaatgttccttcagc
tccctcaccccaggccgcctctacaccgtgaccataactacaaggagtggcaagtatgaa
aatcactccttcagccaagagcggacagtgcctgacaaagtccagggagtcagtgttagc
aactcagccaggagtgactatttaagggtatcctgggtgcatgccactggagactttgat
cactatgaagtcaccattaaaaacaaaaacaacttcattcaaactaaaagcattcccaag
tcagaaaacgaatgtgtatttgttcagctagtccctggacggttgtacagtgtcactgtt
actacaaaaagtggacaatatgaagccaatgaacaagggaatgggagaacaattccagag
cctgttaaggatctaacattgcgcaacaggagcactgaggacttgcatgtgacttggtca
ggagctaatggggatgtcgaccaatatgagatccagctgctcttcaatgacatgaaagta
tttcctccttttcaccttgtaaataccgcaaccgagtatcgatttacttccctaacacca
ggccgccaatacaaaattcttgtcttgacgattagcggggatgtacagcagtcagccttc
attgagggcttcacagttcctagtgctgtcaaaaatattcacatttctcccaatggagca
acagatagcctgacggtgaactggactcctggtgggggagacgttgattcctacacggtg
tcggcattcaggcacagtcaaaaggttgactctcagactattcccaagcacgtctttgag
cacacgttccacagactggaggccggggagcagtaccagatcatgattgcctcagtcagc
gggtccctgaagaatcagataaatgtggttgggcggacagttccagcatctgtccaagga
gtaattgcagacaatgcatacagcagttattccttaatagtaagttggcaaaaagctgct
ggtgtggcagaaagatatgatatcctgcttctaactgaaaatggaatccttctgcgcaac
acatcagagccagccaccactaagcaacacaaatttgaagatctaacaccaggcaagaaa
tacaagatacagatcctaactgtcagtggaggcctctttagcaaggaagcccagactgaa
ggccgaacagtcccagcagctgtcaccgacctgaggatcacagagaactccaccaggcac
ctgtccttccgctggaccgcctcagagggggagctcagctggtacaacatctttttgtac
aacccagatgggaatctccaggagagagctcaagttgacccactagtccagagcttctct
ttccagaacttgctacaaggcagaatgtacaagatggtgattgtaactcacagtggggag
ctgtctaatgagtctttcatatttggtagaacagtcccagcctctgtgagtcatctcagg
gggtccaatcggaacacgacagacagcctttggttcaactggagtccagcctctggggac
tttgacttttatgagctgattctctataatcccaatggcacaaagaaggaaaactggaaa
gacaaggacctgacggagtggcggtttcaaggccttgttcctggaaggaagtacgtgctg
tgggtggtaactcacagtggagatctcagcaataaagtcacagcggagagcagaacagct
ccaagtcctcccagtcttatgtcatttgctgacattgcaaacacatccttggccatcacg
tggaaagggcccccagactggacagactacaacgactttgagctgcagtggttgcccaga
gatgcacttactgtcttcaacccctacaacaacagaaaatcagaaggacgcattgtgtat
ggtcttcgtccagggagatcctatcaattcaacgtcaagactgtcagtggtgattcctgg
aaaacttacagcaaaccaatttttggatctgtgaggacaaagcctgacaagatacaaaac
ctgcattgccggcctcagaactccacggccattgcctgttcttggatccctcctgattct
gactttgatggttatagtattgaatgccggaaaatggacacccaagaagttgagttttcc
agaaagctggagaaagaaaaatctctgctcaacatcatgatgctagtgccccataagagg
tacctggtgtccatcaaagtgcagtcggccggcatgaccagcgaggtggttgaagacagc
actatcacaatgatagaccgcccccctcctccacccccacacattcgtgtgaatgaaaag
gatgtgctaattagcaagtcttccatcaactttactgtcaactgcagctggttcagcgac
accaatggagctgtgaaatacttcacagtggtggtgagagaggctgatggcagtgatgag
ctgaagccagaacagcagcaccctctcccttcctacctggagtacaggcacaatgcctcc
attcgggtgtatcagactaattattttgccagcaaatgtgccgaaaatcctaacagcaac
tccaagagttttaacattaagcttggagcagagatggagagcctaggtggaaaatgcgat
cccactcagcaaaaattctgtgatggaccactgaagccacacactgcctacagaatcagc
attcgagcttttacacagctctttgatgaggacctgaaggaattcacaaagccactctat
tcagacacatttttttctttacccatcactactgaatcagagcccttgtttggagctatt
gaaggtgtgagtgctggtctgtttttaattggcatgctagtggctgttgttgccttattg
atctgcagacagaaagtgagccatggtcgagaaagaccctctgcccgtctgagcattcgt
agggatcgaccattatctgtccacttaaacctgggccagaaaggtaaccggaaaacttct
tgtccaataaaaataaatcagtttgaagggcatttcatgaagctacaggctgactccaac
taccttctatccaaggaatacgaggagttaaaagacgtgggccgaaaccagtcatgtgac
attgcactcttgccggagaatagagggaaaaatcgatacaacaatatattgccctatgat
gccacgcgagtgaagctctccaatgtagatgatgatccttgctctgactacatcaatgcc
agctacatccctggcaacaacttcagaagagaatacattgtcactcagggaccgcttcct
ggcaccaaggatgacttctggaaaatggtgtgggaacaaaacgttcacaacatcgtcatg
gtgacccagtgtgttgagaagggccgagtaaagtgtgatcattactggccagcggaccag
gattccctctactatggggacctcatcctgcagatgctctcagagtccgtcctgcctgag
tggaccatccgggagtttaagatatgcggtgaggaacagcttgatgcacacagactcatc
cgccactttcactatacggtgtggccagaccatggagtcccagaaaccacccagtctctg
atccagtttgtgagaactgtcagggactacatcaacagaagcccgggtgctgggcccact
gtggtgcactgcagtgctggtgtgggtaggactggaacctttattgcattggaccgaatc
ctccagcagttagactccaaagactctgtggacatttatggagcagtgcacgacctaaga
cttcacagggttcacatggtccagactgagtgtcagtatgtctacctacatcagtgtgta
agagatgtcctcagagcaagaaagctacggagtgaacaagaaaaccccttgtttccaatc
tatgaaaatgtgaatccagagtatcacagagatccagtctattcaaggcattga

  All links  
Disease (1)   
   OMIM (1)   
Gene (22)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (15)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (13)   
DNA sequence (57)   
   RefSeq(nuc) (15)   
   GenBank (21)   
   EMBL (21)   
3D Structure (14)   
   PDB (14)   
Protein domain (15)   
   Pfam (15)   
All databases (124)   

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