KEGG   Homo sapiens (human): 5795
Entry
5795              CDS       T01001                                 
Symbol
PTPRJ, CD148, DEP1, HPTP_eta, HPTPeta, R-PTP-ETA, R-PTP-J, SCC1, THC10
Name
(RefSeq) protein tyrosine phosphatase receptor type J
  KO
K05698  receptor-type tyrosine-protein phosphatase eta [EC:3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04520  Adherens junction
hsa05208  Chemical carcinogenesis - reactive oxygen species
Network
nt06223  TNF signaling (cancer)
  Element
N01411  Metals to NFKB signaling pathway
Disease
H00020  Colorectal cancer
H00978  Thrombocytopenia (THC)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    5795 (PTPRJ)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    5795 (PTPRJ)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5795 (PTPRJ)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    5795 (PTPRJ)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     5795 (PTPRJ)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Receptor PTPs
    5795 (PTPRJ)
CD molecules [BR:hsa04090]
 Proteins
  5795 (PTPRJ)
SSDB
Motif
Pfam: Y_phosphatase fn3 PTP_tm Pur_ac_phosph_N Fn3_PBP1 PTP-SAK Tc-R-P Ig_J PTP-NADK DSPc PTPlike_phytase Interfer-bind Y_phosphatase3
Other DBs
NCBI-GeneID: 5795
NCBI-ProteinID: NP_002834
OMIM: 600925
HGNC: 9673
Ensembl: ENSG00000149177
UniProt: Q12913 Q9NPR5
Structure
Position
11:47980559..48170839
AA seq 1337 aa
MKPAAREARLPPRSPGLRWALPLLLLLLRLGQILCAGGTPSPIPDPSVATVATGENGITQ
ISSTAESFHKQNGTGTPQVETNTSEDGESSGANDSLRTPEQGSNGTDGASQKTPSSTGPS
PVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQPWCNITGLRPAT
SYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGNGTASCRVLL
ESIGSHEELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSR
AGSPTAPVHDESLVGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAI
EFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAV
IPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAE
SFQMHITQEGAGNSRVEITTNQSIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRTVP
SAVFDIHVVYVTTTEMWLDWKSPDGASEYVYHLVIESKHGSNHTSTYDKAITLQGLIPGT
LYNITISPEVDHVWGDPNSTAQYTRPSNVSNIDVSTNTTAATLSWQNFDDASPTYSYCLL
IEKAGNSSNATQVVTDIGITDATVTELIPGSSYTVEIFAQVGDGIKSLEPGRKSFCTDPA
SMASFDCEVVPKEPALVLKWTCPPGANAGFELEVSSGAWNNATHLESCSSENGTEYRTEV
TYLNFSTSYNISITTVSCGKMAAPTRNTCTTGITDPPPPDGSPNITSVSHNSVKVKFSGF
EASHGPIKAYAVILTTGEAGHPSADVLKYTYEDFKKGASDTYVTYLIRTEEKGRSQSLSE
VLKYEIDVGNESTTLGYYNGKLEPLGSYRACVAGFTNITFHPQNKGLIDGAESYVSFSRY
SDAVSLPQDPGVICGAVFGCIFGALVIVTVGGFIFWRKKRKDAKNNEVSFSQIKPKKSKL
IRVENFEAYFKKQQADSNCGFAEEYEDLKLVGISQPKYAAELAENRGKNRYNNVLPYDIS
RVKLSVQTHSTDDYINANYMPGYHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIIMLTK
CVEQGRTKCEEYWPSKQAQDYGDITVAMTSEIVLPEWTIRDFTVKNIQTSESHPLRQFHF
TSWPDHGVPDTTDLLINFRYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIE
NENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIVRSQKDSKVDLIYQNTTAMTIY
ENLAPVTTFGKTNGYIA
NT seq 4014 nt   +upstreamnt  +downstreamnt
atgaagccggcggcgcgggaggcgcggctgcctccgcgctcgcccgggctgcgctgggcg
ctgccgctgctgctgctgctgctgcgcctgggccagatcctgtgcgcaggtggcacccct
agtccaattcctgacccttcagtagcaactgttgccacaggggaaaatggcataacgcag
atcagcagtacagcagaatcctttcataaacagaatggaactggaacacctcaggtggaa
acaaacaccagtgaggatggtgaaagctctggagccaacgatagtttaagaacacctgaa
caaggatctaatgggactgatggggcatctcaaaaaactcccagtagcactgggcccagt
cctgtgtttgacattaaagctgtttccatcagtccaaccaatgtgatcttaacttggaaa
agtaatgacacagctgcttctgagtacaagtatgtagtaaagcataagatggaaaatgag
aagacaattactgttgtgcatcaaccatggtgtaacatcacaggcttacgtccagcgact
tcatatgtattctccatcactccaggaataggcaatgagacttggggagatcccagagtc
ataaaagtcatcacagagccgatcccagtttctgatctccgtgttgccctcacgggtgtg
aggaaggctgctctctcctggagcaatggcaatggcactgcctcctgccgggttcttctt
gaaagcattggaagccatgaggagttgactcaagactcaagacttcaggtcaatatctcg
ggcctgaagccaggggttcaatacaacatcaacccgtatcttctacaatcaaataagaca
aagggagaccccttgggcacagaaggtggcttggatgccagcaatacagagagaagccgg
gcagggagccccaccgcccctgtgcatgatgagtccctcgtgggacctgtggacccatcc
tccggccagcagtcccgagacacggaagtcctgcttgtcgggttagagcctggcacccga
tacaatgccaccgtttattcccaagcagcgaatggcacagaaggacagccccaggccata
gagttcaggacaaatgctattcaggtttttgacgtcaccgctgtgaacatcagtgccaca
agcctgaccctgatctggaaagtcagcgataacgagtcgtcatctaactatacctacaag
atacatgtggcgggggagacagattcttccaatctcaacgtcagtgagcctcgcgctgtc
atccccggactccgctccagcaccttctacaacatcacagtgtgtcctgtcctaggtgac
atcgagggcacgccgggcttcctccaagtgcacaccccccctgttccagtttctgacttc
cgagtgacagtggtcagcacgacggagatcggcttagcatggagcagccatgatgcagaa
tcatttcagatgcatatcacacaggagggagctggcaattctcgggtagaaataaccacc
aaccaaagtattatcattggtggcttgttccctggaaccaagtattgctttgaaatagtt
ccaaaaggaccaaatgggactgaaggggcatctcggacagtttgcaatagaactgttccc
agtgcagtgtttgacatccacgtggtctacgtcaccaccacggagatgtggctggactgg
aagagccctgacggtgcttccgagtatgtctaccatttagtcatagagtccaagcatggc
tctaaccacacaagcacgtatgacaaagcgattactctccagggcctgattccgggcacc
ttatataacatcaccatctctccagaagtggaccacgtctggggggaccccaactccact
gcacagtacacacggcccagcaatgtgtccaacattgatgtaagtaccaacaccacagca
gcaactttaagttggcagaactttgatgacgcctctcccacgtactcctactgccttctt
attgagaaggctggaaattccagcaacgcaacacaagtagtcacggacattggaattact
gacgctacagtcactgaattaatacctggctcatcatacacagtggagatctttgcacaa
gtaggggatgggatcaagtcactggaacctggccggaagtcattctgtacagatcctgcg
tccatggcctccttcgactgcgaagtggtccccaaagagccagccctggttctcaaatgg
acctgccctcctggcgccaatgcaggctttgagctggaggtcagcagtggagcctggaac
aatgcgacccacctggagagctgctcctctgagaatggcactgagtatagaacggaagtc
acgtatttgaatttttctacctcgtacaacatcagcatcaccactgtgtcctgtggaaag
atggcagcccccacccggaacacctgcactactggcatcacagatccccctcctccagat
ggatcccctaatattacatctgtcagtcacaattcagtaaaggtcaagttcagtggattt
gaagccagccacggacccatcaaagcctatgctgtcattctcaccaccggggaagctggt
cacccttctgcagatgtcctgaaatacacgtatgaggatttcaaaaagggagcctcagat
acttatgtgacatacctcataagaacagaagaaaagggacgttctcagagcttgtctgaa
gttttgaaatatgaaattgacgttgggaatgagtcaaccacacttggttattacaatggg
aagctggaacctctgggctcctaccgggcttgtgtggctggcttcaccaacattaccttc
caccctcaaaacaaggggctcattgatggggctgagagctatgtgtccttcagtcgctac
tcagatgctgtttccttgccccaggatccaggtgtcatctgtggagcggtttttggctgt
atctttggtgccctggttattgtgactgtgggaggcttcatcttctggagaaagaagagg
aaagatgcaaagaataatgaagtgtccttttctcaaattaaacctaaaaaatctaagtta
atcagagtggagaattttgaggcctacttcaagaagcagcaagctgactccaactgtggg
ttcgcagaggaatacgaagatctgaagcttgttggaattagtcaacctaaatatgcagca
gaactggctgagaatagaggaaagaatcgctataataatgttctgccctatgatatttcc
cgtgtcaaactttcggtccagacccattcaacggatgactacatcaatgccaactacatg
cctggctaccactccaagaaagattttattgccacacaaggacctttaccgaacactttg
aaagatttttggcgtatggtttgggagaaaaatgtatatgccatcattatgttgactaaa
tgtgttgaacagggaagaaccaaatgtgaggagtattggccctccaagcaggctcaggac
tatggagacataactgtggcaatgacatcagaaattgttcttccggaatggaccatcaga
gatttcacagtgaaaaatatccagacaagtgagagtcaccctctgagacagttccatttc
acctcctggccagaccacggtgttcccgacaccactgacctgctcatcaacttccggtac
ctcgttcgtgactacatgaagcagagtcctcccgaatcgccgattctggtgcattgcagt
gctggggtcggaaggacgggcactttcattgccattgatcgtctcatctaccagatagag
aatgagaacaccgtggatgtgtatgggattgtgtatgaccttcgaatgcataggccttta
atggtgcagacagaggaccagtatgttttcctcaatcagtgtgttttggatattgtcaga
tcccagaaagactcaaaagtagatcttatctaccagaacacaactgcaatgacaatctat
gaaaaccttgcgcccgtgaccacatttggaaagaccaatggttacatcgcctaa

  All links  
Disease (3)   
   OMIM (3)   
Gene (29)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (24)   
   RefSeq(nuc) (6)   
   GenBank (9)   
   EMBL (9)   
3D Structure (5)   
   PDB (5)   
Protein domain (12)   
   Pfam (12)   
All databases (82)   

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