KEGG   Homo sapiens (human): 580
Entry
580               CDS       T01001                                 

Gene name
BARD1
Definition
(RefSeq) BRCA1 associated RING domain 1
  KO
K10683  BRCA1-associated RING domain protein 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa03440  Homologous recombination
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03440 Homologous recombination
    580 (BARD1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    580 (BARD1)
   04121 Ubiquitin system [BR:hsa04121]
    580 (BARD1)
   03036 Chromosome and associated proteins [BR:hsa03036]
    580 (BARD1)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    580 (BARD1)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Negative regulators of mRNA 3' end processing
     580 (BARD1)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   BRCC complex
    580 (BARD1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation and ciliogenesis proteins
   Centrosome duplication proteins
    Regulators of centriole replication
     580 (BARD1)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    BRCA1-core complex
     580 (BARD1)
SSDB
Motif
Pfam: zf-RING_6 Ank_2 Ank_4 Ank_5 Ank Ank_3 BRCT_2 BRCT zf-RING_5 zf-C3HC4 Siva zf-C3HC4_3 zf-RING_UBOX zf-C3HC4_2 zf-RING_2
Other DBs
NCBI-GeneID: 580
NCBI-ProteinID: NP_000456
OMIM: 601593
HGNC: 952
Ensembl: ENSG00000138376
Vega: OTTHUMG00000133016
Pharos: Q99728(Tbio)
UniProt: Q99728 A0AVN2
Structure
PDB: 
2NTE 3C5R 2R1Z 3FA2 1JM7

Position
2q35
AA seq 777 aa
MPDNRQPRNRQPRIRSGNEPRSAPAMEPDGRGAWAHSRAALDRLEKLLRCSRCTNILREP
VCLGGCEHIFCSNCVSDCIGTGCPVCYTPAWIQDLKINRQLDSMIQLCSKLRNLLHDNEL
SDLKEDKPRKSLFNDAGNKKNSIKMWFSPRSKKVRYVVSKASVQTQPAIKKDASAQQDSY
EFVSPSPPADVSERAKKASARSGKKQKKKTLAEINQKWNLEAEKEDGEFDSKEESKQKLV
SFCSQPSVISSPQINGEIDLLASGSLTESECFGSLTEVSLPLAEQIESPDTKSRNEVVTP
EKVCKNYLTSKKSLPLENNGKRGHHNRLSSPISKRCRTSILSTSGDFVKQTVPSENIPLP
ECSSPPSCKRKVGGTSGRKNSNMSDEFISLSPGTPPSTLSSSSYRRVMSSPSAMKLLPNM
AVKRNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELL
LQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDDESMK
SLLLLPEKNESSSASHCSVMNTGQRRDGPLVLIGSGLSSEQQKMLSELAVILKAKKYTEF
DSTVTHVVVPGDAVQSTLKCMLGILNGCWILKFEWVKACLRRKVCEQEEKYEIPEGPRRS
RLNREQLLPKLFDGCYFYLWGTFKHHPKDNLIKLVTAGGGQILSRKPKPDSDVTQTINTV
AYHARPDSDQRFCTQYIIYEDLCNYHPERVRQGKVWKAPSSWFIDCVMSFELLPLDS
NT seq 2334 nt   +upstreamnt  +downstreamnt
atgccggataatcggcagccgaggaaccggcagccgaggatccgctccgggaacgagcct
cgttccgcgcccgccatggaaccggatggtcgcggtgcctgggcccacagtcgcgccgcg
ctcgaccgcctggagaagctgctgcgctgctcgcgttgtactaacattctgagagagcct
gtgtgtttaggaggatgtgagcacatcttctgtagtaattgtgtaagtgactgcattgga
actggatgtccagtgtgttacaccccggcctggatacaagacttgaagataaatagacaa
ctggacagcatgattcaactttgtagtaagcttcgaaatttgctacatgacaatgagctg
tcagatttgaaagaagataaacctaggaaaagtttgtttaatgatgcaggaaacaagaag
aattcaattaaaatgtggtttagccctcgaagtaagaaagtcagatatgttgtgagtaaa
gcttcagtgcaaacccagcctgcaataaaaaaagatgcaagtgctcagcaagactcatat
gaatttgtttccccaagtcctcctgcagatgtttctgagagggctaaaaaggcttctgca
agatctggaaaaaagcaaaaaaagaaaactttagctgaaatcaaccaaaaatggaattta
gaggcagaaaaagaagatggtgaatttgactccaaagaggaatctaagcaaaagctggta
tccttctgtagccaaccatctgttatctccagtcctcagataaatggtgaaatagactta
ctagcaagtggctccttgacagaatctgaatgttttggaagtttaactgaagtctcttta
ccattggctgagcaaatagagtctccagacactaagagcaggaatgaagtagtgactcct
gagaaggtctgcaaaaattatcttacatctaagaaatctttgccattagaaaataatgga
aaacgtggccatcacaatagactttccagtcccatttctaagagatgtagaaccagcatt
ctgagcaccagtggagattttgttaagcaaacggtgccctcagaaaatataccattgcct
gaatgttcttcaccaccttcatgcaaacgtaaagttggtggtacatcagggaggaaaaac
agtaacatgtccgatgaattcattagtctttcaccaggtacaccaccttctacattaagt
agttcaagttacaggcgagtgatgtctagtccctcagcaatgaagctgttgcccaatatg
gctgtgaaaagaaatcatagaggagagactttgctccatattgcttctattaagggcgac
ataccttctgttgaataccttttacaaaatggaagtgatccaaatgttaaagaccatgct
ggatggacaccattgcatgaagcttgcaatcatgggcacctgaaggtagtggaattattg
ctccagcataaggcattggtgaacaccaccgggtatcaaaatgactcaccacttcacgat
gcagccaagaatgggcatgtggatatagtcaagctgttactttcctatggagcctccaga
aatgctgttaatatatttggtctgcggcctgtcgattatacagatgatgaaagtatgaaa
tcgctattgctgctaccagagaagaatgaatcatcctcagctagccactgctcagtaatg
aacactgggcagcgtagggatggacctcttgtacttataggcagtgggctgtcttcagaa
caacagaaaatgctcagtgagcttgcagtaattcttaaggctaaaaaatatactgagttt
gacagtacagtaactcatgttgttgttcctggtgatgcagttcaaagtaccttgaagtgt
atgcttgggattctcaatggatgctggattctaaaatttgaatgggtaaaagcatgtcta
cgaagaaaagtatgtgaacaggaagaaaagtatgaaattcctgaaggtccacgcagaagc
aggctcaacagagaacagctgttgccaaagctgtttgatggatgctacttctatttgtgg
ggaaccttcaaacaccatccaaaggacaaccttattaagctcgtcactgcaggtgggggc
cagatcctcagtagaaagcccaagccagacagtgacgtgactcagaccatcaatacagtc
gcataccatgcgagacccgattctgatcagcgcttctgcacacagtatatcatctatgaa
gatttgtgtaattatcacccagagagggttcggcagggcaaagtctggaaggctccttcg
agctggtttatagactgtgtgatgtcctttgagttgcttcctcttgacagctga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (2)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (10)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (53)   
   RefSeq(nuc) (11)   
   GenBank (21)   
   EMBL (21)   
Protein domain (15)   
   Pfam (15)   
All databases (106)   

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