KEGG   Homo sapiens (human): 5825
Entry
5825              CDS       T01001                                 
Symbol
ABCD3, ABC43, CBAS5, PMP70, PXMP1, ZWS2
Name
(RefSeq) ATP binding cassette subfamily D member 3
  KO
K05677  ATP-binding cassette, subfamily D (ALD), member 3 [EC:7.6.2.4]
Organism
hsa  Homo sapiens (human)
Pathway
hsa02010  ABC transporters
hsa04146  Peroxisome
Disease
H00628  Congenital bile acid synthesis defect
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    5825 (ABCD3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    5825 (ABCD3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    5825 (ABCD3)
Enzymes [BR:hsa01000]
 7. Translocases
  7.6  Catalysing the translocation of other compounds
   7.6.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.6.2.4  ABC-type fatty-acyl-CoA transporter
     5825 (ABCD3)
Transporters [BR:hsa02000]
 ABC transporters, eukaryotic type
  ABCD (ALD) subfamily
   ABCD3 subgroup
    5825 (ABCD3)
SSDB
Motif
Pfam: ABC_membrane_2 ABC_tran AAA_23 SMC_N AAA_21 AAA_29 Rad17 AAA_27
Other DBs
NCBI-GeneID: 5825
NCBI-ProteinID: NP_002849
OMIM: 170995
HGNC: 67
Ensembl: ENSG00000117528
UniProt: P28288
Structure
Position
1:94385131..94518663
AA seq 659 aa
MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVD
KVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRK
DFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN
RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLVVS
GLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTVHSVFRKLV
EHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHPRHLKSTHSELLEDYYQS
GRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGKYERTMVSQQEKGIEG
VQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKS
SLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDL
VLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSA
VSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKQITEDTVEFGS
NT seq 1980 nt   +upstreamnt  +downstreamnt
atggcggccttcagcaagtacttgacggcgcgaaactcctcgctggctggtgccgcgttc
ctgctgctctgcctgctccacaagcggcgccgcgccctcggcctgcacggtaagaaaagt
ggaaaaccaccattacagaacaatgagaaagaggggaaaaaggagcgagctgtggtggac
aaggtgtttttctcaaggctcatacagattctgaaaatcatggtccctagaacattttgt
aaagagacaggttacttggtacttattgctgttatgctggtgtctcgaacatattgtgat
gtttggatgattcaaaatgggacactaattgaaagtggtatcattggtcgtagcaggaaa
gatttcaagagatacttactcaacttcatcgctgccatgcctcttatctctctggttaat
aacttcttgaagtatgggttaaatgagcttaaactgtgcttccgagtaaggctcactaaa
tacctctatgaggagtatcttcaagctttcacatattataaaatggggaatctggacaac
agaatagctaatccagaccagctgcttacacaagatgtagaaaaattttgtaacagtgta
gtcgatctgtattcaaatcttagtaagccatttttagacatagttttgtatatctttaag
ttaacgagtgcaattggagctcagggcccagcgagcatgatggcctacttggttgtttct
gggctattcctaactcgacttcgaagacccattggtaagatgacaataactgagcaaaag
tatgaaggagaatatagatatgttaattctcggctcatcacaaacagtgaagaaattgcc
ttttacaatgggaataaaagagaaaagcagacagtccactcagtcttccgaaaactggtg
gaacacctacataatttcattttgtttcggttttcaatgggcttcattgatagtattatt
gccaaataccttgccactgttgttggttacctagttgtcagtcgccctttcttagatttg
tctcatcctcgacatctcaagagtacacattcggaacttctagaggattactaccaaagt
ggaagaatgcttttgcgaatgtctcaagctctgggtcgaatagttttggctgggcgtgaa
atgactagattggccggttttactgctcggattacagaattaatgcaagtactgaaggat
ttaaatcatggcaaatatgagcgcacaatggtctcacaacaggaaaagggtattgaagga
gtacaagtcattcccttgatacctggtgctggagaaatcattattgcagataacattata
aagtttgatcatgttcctttagcaacgccaaatggagatgttttgatccgagaccttaat
tttgaagttcgatctggggctaatgttctaatttgtggtccaaatggctgcggaaagagt
tcacttttccgtgttcttggtgaattatggcctctttttggaggacgtctaactaaacct
gaaagaggaaaattattttatgttcctcagagaccttacatgacccttggaacacttcga
gatcaagtgatatatccagatggacgagaagatcagaaaaggaagggaatttctgaccta
gtactgaaggaatacttagacaatgtccagttgggtcatatccttgaacgtgaaggaggc
tgggacagtgttcaggattggatggacgtactcagtggtggagaaaagcaaagaatggcg
atggcaagattattttatcataaaccccagtttgccattttggatgaatgcacaagtgca
gttagtgtcgacgtggaaggctacatttatagtcattgtcgaaaggttggcatcactctc
ttcactgtgtctcataggaaatctctttggaaacatcatgagtactacctgcatatggat
ggcagaggcaactatgaattcaaacagataacagaagatacagttgagtttggctcttag

  All links  
Disease (2)   
   OMIM (2)   
Gene (7)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (17)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (15)   
DNA sequence (37)   
   RefSeq(nuc) (15)   
   GenBank (11)   
   EMBL (11)   
3D Structure (2)   
   PDB (2)   
Protein domain (8)   
   Pfam (8)   
All databases (73)   

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