KEGG   Homo sapiens (human): 58497
Entry
58497             CDS       T01001                                 
Symbol
PRUNE1, DRES-17, DRES17, H-PRUNE, HTCD37, NMIHBA, PRUNE
Name
(RefSeq) prune exopolyphosphatase 1
  KO
K01514  exopolyphosphatase [EC:3.6.1.11]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00230  Purine metabolism
hsa01100  Metabolic pathways
Disease
H02461  Neurodevelopmental disorder with microcephaly
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    58497 (PRUNE1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.11  exopolyphosphatase
     58497 (PRUNE1)
SSDB
Motif
Pfam: DHHA2 DHH
Other DBs
NCBI-GeneID: 58497
NCBI-ProteinID: NP_067045
OMIM: 617413
HGNC: 13420
Ensembl: ENSG00000143363
UniProt: Q86TP1
Position
1:151008449..151035713
AA seq 453 aa
MEDYLQGCRAALQESRPLHVVLGNEACDLDSTVSALALAFYLAKTTEAEEVFVPVLNIKR
SELPLRGDIVFFLQKVHIPESILIFRDEIDLHALYQAGQLTLILVDHHILSKSDTALEEA
VAEVLDHRPIEPKHCPPCHVSVELVGSCATLVTERILQGAPEILDRQTAALLHGTIILDC
VNMDLKIGKATPKDSKYVEKLEALFPDLPKRNDIFDSLQKAKFDVSGLTTEQMLRKDQKT
IYRQGVKVAISAIYMDLEAFLQRSNLLADLHAFCQAHSYDVLVAMTIFFNTHNEPVRQLA
IFCPHVALQTTICEVLERSHSPPLKLTPASSTHPNLHAYLQGNTQVSRKKLLPLLQEALS
AYFDSMKIPSGQPETADVSREQVDKELDRASNSLISGLSQDEEDPPLPPTPMNSLVDECP
LDQGLPKLSAEAVFEKCSQISLSQSTTASLSKK
NT seq 1362 nt   +upstreamnt  +downstreamnt
atggaggactacctgcagggttgtcgagctgctctgcaggagtcccgacctctacatgtt
gtgctgggaaatgaagcctgtgatttggactccacagtgtctgctcttgccctggctttt
tacctagcaaagacaactgaggctgaggaagtctttgtgccagttttaaatataaaacgt
tctgaactacctctgcgaggtgacattgtcttctttcttcagaaggttcatattccagag
agtatcttgatttttcgggatgagattgacctccatgcattataccaggctggccaactc
accctcatccttgtcgaccatcatatcttatccaaaagtgacacagccctagaggaggca
gtagcagaggtgctagaccatcgacccatcgagccgaaacactgccctccctgccatgtt
tcagttgagctggtggggtcctgtgctaccctggtgaccgagagaatcctgcagggggca
ccagagatcttggacaggcaaactgcagcccttctgcatggaaccatcatcctggactgt
gtcaacatggaccttaaaattggaaaggcaaccccaaaggacagcaaatatgtggagaaa
ctagaggcccttttcccagacctacccaagagaaatgatatatttgattccctacaaaag
gcaaagtttgatgtatcaggactgaccactgagcagatgctgagaaaagaccagaagact
atctatagacaaggcgtcaaggtggccattagtgcaatatatatggatttggaggccttt
ctgcagaggtctaacctccttgcagatctccatgctttctgccaggctcacagctatgat
gtcctggttgccatgactatctttttcaacactcacaatgagccagtgcggcagttggct
attttctgtccccatgtggcactccaaacaacgatctgtgaagtcctggaacgctcccac
tctccacccctgaagctgacccctgcctcaagtacccaccctaacctccatgcctatctt
caaggcaacacccaggtctctcgaaagaaacttctgcccctgctccaggaagccctgtca
gcatattttgactccatgaagatcccttcaggacagcctgagacagcagatgtgtccagg
gagcaagtggacaaggaattggacagggcaagtaactccctgatttctggcctgagtcaa
gatgaggaggaccctccgctgcccccgacgcccatgaacagcttggtggatgagtgccct
ctagatcaggggctgcctaaactctctgctgaggccgtcttcgagaagtgcagtcagatc
tcactgtcacagtctaccacagcctccctgtccaagaagtga

  All links  
Disease (2)   
   OMIM (2)   
Gene (11)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (16)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (14)   
DNA sequence (54)   
   RefSeq(nuc) (18)   
   GenBank (18)   
   EMBL (18)   
Protein domain (2)   
   Pfam (2)   
All databases (85)   

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