KEGG   Homo sapiens (human): 58511
Entry
58511             CDS       T01001                                 
Symbol
DNASE2B, DLAD
Name
(RefSeq) deoxyribonuclease 2 beta
  KO
K01158  deoxyribonuclease II [EC:3.1.22.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04142  Lysosome
hsa04623  Cytosolic DNA-sensing pathway
Network
nt06520  CGAS-STING signaling
  Element
N01571  DNA degradation by extracellular/endolysosomal DNAse
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    58511 (DNASE2B)
 09150 Organismal Systems
  09151 Immune system
   04623 Cytosolic DNA-sensing pathway
    58511 (DNASE2B)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.22  Endodeoxyribonucleases producing 3'-phosphomonoesters
    3.1.22.1  deoxyribonuclease II
     58511 (DNASE2B)
SSDB
Motif
Pfam: DNase_II
Other DBs
NCBI-GeneID: 58511
NCBI-ProteinID: NP_067056
OMIM: 608057
HGNC: 28875
Ensembl: ENSG00000137976
UniProt: Q8WZ79 Q66K39
Position
1:84398484..84415018
AA seq 361 aa
MKQKMMARLLRTSFALLFLGLFGVLGAATISCRNEEGKAVDWFTFYKLPKRQNKESGETG
LEYLYLDSTTRSWRKSEQLMNDTKSVLGRTLQQLYEAYASKSNNTAYLIYNDGVPKPVNY
SRKYGHTKGLLLWNRVQGFWLIHSIPQFPPIPEEGYDYPPTGRRNGQSGICITFKYNQYE
AIDSQLLVCNPNVYSCSIPATFHQELIHMPQLCTRASSSEIPGRLLTTLQSAQGQKFLHF
AKSDSFLDDIFAAWMAQRLKTHLLTETWQRKRQELPSNCSLPYHVYNIKAIKLSRHSYFS
SYQDHAKWCISQKGTKNRWTCIGDLNRSPHQAFRSGGFICTQNWQIYQAFQGLVLYYESC
K
NT seq 1086 nt   +upstreamnt  +downstreamnt
atgaaacagaaaatgatggcaagactgctaagaacatcctttgctttgctcttccttggc
ctctttggggtgctgggggcagcaacaatttcatgcagaaatgaagaagggaaagctgtg
gactggtttactttttataagttacctaaaagacaaaacaaggaaagtggagagactggg
ttagagtacctgtacctagactctacaactagaagctggaggaagagtgagcaactaatg
aatgacaccaagagtgttttgggaaggacattacaacagctatatgaagcatatgcctct
aagagtaacaacacagcctatctaatatacaatgatggagtccctaaacctgtgaattac
agcagaaagtatggacacaccaaaggtttactgctgtggaacagagttcaagggttctgg
ctgattcattccatccctcagtttcctccaattccggaagaaggctatgattatccaccc
acagggagacgaaatggacaaagtggcatctgcataactttcaagtacaaccagtatgag
gcaatagattctcagctcttggtctgcaaccccaacgtctatagctgctccatcccagcc
acctttcaccaggagctcattcacatgccccagctgtgcaccagggccagctcatcagag
attcctggcaggctcctcaccacacttcagtcggcccagggacaaaaattcctccatttt
gcaaagtcggattcttttcttgacgacatctttgcagcctggatggctcaacggctgaag
acacacttgttaacagaaacctggcagcgaaaaagacaagagcttccttcaaactgctcc
cttccttaccatgtctacaatataaaagcaattaaattatcacgacactcttatttcagt
tcttatcaagatcatgccaagtggtgtatttcccaaaagggcaccaaaaatcgctggaca
tgtattggagacctaaatcggagtccacaccaagccttcagaagtggaggattcatttgt
acccagaattggcaaatttaccaagcatttcaaggattagtattatactatgaaagctgt
aagtaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (9)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (18)   
   RefSeq(nuc) (6)   
   GenBank (6)   
   EMBL (6)   
Protein domain (1)   
   Pfam (1)   
All databases (48)   

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