KEGG   Homo sapiens (human): 5869
Entry
5869              CDS       T01001                                 
Symbol
RAB5B
Name
(RefSeq) ras-related protein Rab-5B isoform 1
  KO
K07888  Ras-related protein Rab-5B
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04137  Mitophagy - animal
hsa04144  Endocytosis
hsa04145  Phagosome
hsa04148  Efferocytosis
hsa04962  Vasopressin-regulated water reabsorption
hsa05132  Salmonella infection
hsa05146  Amoebiasis
hsa05152  Tuberculosis
Network
nt06181  Salmonella
nt06536  Mitophagy
  Element
N01302  Early endosomal fusion
N01303  Salmonella SopB to Early endosomal fusion
N01760  Endosomal Rab cycles
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    5869 (RAB5B)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    5869 (RAB5B)
   04145 Phagosome
    5869 (RAB5B)
   04137 Mitophagy - animal
    5869 (RAB5B)
   04148 Efferocytosis
    5869 (RAB5B)
 09150 Organismal Systems
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    5869 (RAB5B)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    5869 (RAB5B)
   05152 Tuberculosis
    5869 (RAB5B)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    5869 (RAB5B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    5869 (RAB5B)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5869 (RAB5B)
   04031 GTP-binding proteins [BR:hsa04031]
    5869 (RAB5B)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab GTPases
    5869 (RAB5B)
 Endosome - Lysosome transport
    5869 (RAB5B)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   5869 (RAB5B)
  Exosomal proteins of other body fluids (saliva and urine)
   5869 (RAB5B)
  Exosomal proteins of colorectal cancer cells
   5869 (RAB5B)
  Exosomal proteins of melanoma cells
   5869 (RAB5B)
GTP-binding proteins [BR:hsa04031]
 Small (monomeric) G-proteins
  Rab Family
   Rab5/17/22/31 [OT]
    5869 (RAB5B)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU MMR_HSR1 Gtr1_RagA RsgA_GTPase AAA_16
Other DBs
NCBI-GeneID: 5869
NCBI-ProteinID: NP_001238965
OMIM: 179514
HGNC: 9784
UniProt: P61020
Structure
Position
12:55973949..55996683
AA seq 215 aa
MTSRSTARPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQ
SVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQR
QASPSIVIALAGNKADLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKK
LPKSEPQNLGGAAGRSRGVDLHEQSQQNKSQCCSN
NT seq 648 nt   +upstreamnt  +downstreamnt
atgactagcagaagcacagctaggcccaatgggcaaccccaggccagcaaaatttgccag
ttcaaattggtcctgctgggagaatctgcagtgggaaagtcaagcctggtattacgtttt
gtcaaagggcagttccatgagtaccaggagagcaccattggagcggccttcctcacccag
tccgtttgtctagatgacacaacagtgaagtttgagatctgggacacagctgggcaggag
cgatatcacagcttagcccccatgtactacaggggtgcccaagctgcaatcgtggtttac
gacattactaatcaggaaacctttgcccgagcaaagacatgggtgaaggaactacagcga
caggccagtcctagcatcgttattgccctggcagggaacaaagctgacctggccaacaaa
cgtatggtggagtatgaagaggcccaggcatatgcagatgacaacagcttattgttcatg
gagacttcagccaagacagctatgaacgtgaatgatctcttcctggcaatagctaagaag
ttgccaaagagtgaaccccagaatctgggaggtgcagcaggccgaagccggggtgtggat
ctccatgaacagtcccagcagaacaagagccagtgttgtagcaactga

  All links  
Disease (1)   
   OMIM (1)   
Gene (18)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   RIKEN BRC-DNA (8)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (40)   
   RefSeq(nuc) (6)   
   GenBank (17)   
   EMBL (17)   
3D Structure (1)   
   PDB (1)   
Protein domain (8)   
   Pfam (8)   
All databases (76)   

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