KEGG   Homo sapiens (human): 5906
Entry
5906              CDS       T01001                                 

Gene name
RAP1A, C21KG, G-22K, KREV-1, KREV1, RAP1, SMGP21
Definition
(RefSeq) RAP1A, member of RAS oncogene family
  KO
K04353  Ras-related protein Rap-1A
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
hsa04014  Ras signaling pathway
hsa04015  Rap1 signaling pathway
hsa04024  cAMP signaling pathway
hsa04062  Chemokine signaling pathway
hsa04510  Focal adhesion
hsa04530  Tight junction
hsa04611  Platelet activation
hsa04670  Leukocyte transendothelial migration
hsa04720  Long-term potentiation
hsa04722  Neurotrophin signaling pathway
hsa04934  Cushing syndrome
hsa04972  Pancreatic secretion
hsa05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    5906 (RAP1A)
   04014 Ras signaling pathway
    5906 (RAP1A)
   04015 Rap1 signaling pathway
    5906 (RAP1A)
   04024 cAMP signaling pathway
    5906 (RAP1A)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    5906 (RAP1A)
   04530 Tight junction
    5906 (RAP1A)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    5906 (RAP1A)
   04670 Leukocyte transendothelial migration
    5906 (RAP1A)
   04062 Chemokine signaling pathway
    5906 (RAP1A)
  09154 Digestive system
   04972 Pancreatic secretion
    5906 (RAP1A)
  09156 Nervous system
   04720 Long-term potentiation
    5906 (RAP1A)
   04722 Neurotrophin signaling pathway
    5906 (RAP1A)
 09160 Human Diseases
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    5906 (RAP1A)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    5906 (RAP1A)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:hsa04031]
    5906 (RAP1A)
GTP-binding proteins [BR:hsa04031]
 Small (monomeric) G-proteins
  Ras Family
   Rap [OT]
    5906 (RAP1A)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase G-alpha
Other DBs
NCBI-GeneID: 5906
NCBI-ProteinID: NP_001010935
OMIM: 179520
HGNC: 9855
Ensembl: ENSG00000116473
Vega: OTTHUMG00000011959
Pharos: P62834(Tchem)
UniProt: P62834 A8KAH9
Structure
PDB: 
4KVG 1C1Y 3KUC 1GUA

Position
1p13.2
AA seq 184 aa
MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG
TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL
EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS
CLLL
NT seq 555 nt   +upstreamnt  +downstreamnt
atgcgtgagtacaagctagtggtccttggttcaggaggcgttgggaagtctgctctgaca
gttcagtttgttcagggaatttttgttgaaaaatatgacccaacgatagaagattcctac
agaaagcaagttgaagtcgattgccaacagtgtatgctcgaaatcctggatactgcaggg
acagagcaatttacagcaatgagggatttgtatatgaagaacggccaaggttttgcacta
gtatattctattacagctcagtccacgtttaacgacttacaggacctgagggaacagatt
ttacgggttaaggacacggaagatgttccaatgattttggttggcaataaatgtgacctg
gaagatgagcgagtagttggcaaagagcagggccagaatttagcaagacagtggtgtaac
tgtgcctttttagaatcttctgcaaagtcaaagatcaatgttaatgagatattttatgac
ctggtcagacagataaataggaaaacaccagtggaaaagaagaagcctaaaaagaaatca
tgtctgctgctctag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (14)   
   KEGG PATHWAY (14)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (49)   
   RefSeq(nuc) (5)   
   GenBank (22)   
   EMBL (22)   
Protein domain (7)   
   Pfam (7)   
All databases (101)   

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