KEGG   Homo sapiens (human): 5928
Entry
5928              CDS       T01001                                 
Symbol
RBBP4, NURF55, RBAP48, lin-53
Name
(RefSeq) RB binding protein 4, chromatin remodeling factor
  KO
K10752  histone-binding protein RBBP4
Organism
hsa  Homo sapiens (human)
Pathway
hsa03082  ATP-dependent chromatin remodeling
hsa03083  Polycomb repressive complex
hsa04218  Cellular senescence
Network
nt06523  Epigenetic regulation by Polycomb complexes
  Element
N01577  Gene silencing by methylation of H3K27 and ubiquitination of H2AK119
N01586  Activation of PRC2.2 by ubiquitination of H2AK119
N01614  Activation of PRC2.2 by ubiquitination of H2AK119 in germline genes
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03082 ATP-dependent chromatin remodeling
    5928 (RBBP4)
   03083 Polycomb repressive complex
    5928 (RBBP4)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    5928 (RBBP4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    5928 (RBBP4)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Nucleosome assembly factors
   Histone chaperones
    CAF-1
     5928 (RBBP4)
  Histone modification proteins
   HAT complexes
    HATB complex
     5928 (RBBP4)
   HDAC complexes
    Sin3A-HDAC complex
     5928 (RBBP4)
   Polycomb repressive complex (PRC) and associated proteins
    PRC2.1
     5928 (RBBP4)
    PRC2.2
     5928 (RBBP4)
  Centromeric chromatin formation proteins
   Kinetochore proteins
    MIS16-MIS18 complex
     5928 (RBBP4)
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    5928 (RBBP4)
  Chromatin remodeling factors
   NuRD complex
    5928 (RBBP4)
   NuRF complex
    5928 (RBBP4)
   NuRF complex (fruit fly)
    5928 (RBBP4)
SSDB
Motif
Pfam: WD40 CAF1C_H4-bd ANAPC4_WD40 eIF2A MIOS_WD40 NBCH_WD40
Other DBs
NCBI-GeneID: 5928
NCBI-ProteinID: NP_005601
OMIM: 602923
HGNC: 9887
Ensembl: ENSG00000162521
UniProt: Q09028
Structure
Position
1:32651208..32686211
AA seq 425 aa
MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKD
FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK
INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG
YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE
SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL
WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAE
DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP
EGQGS
NT seq 1278 nt   +upstreamnt  +downstreamnt
atggccgacaaggaagcagccttcgacgacgcagtggaagaacgagtgatcaacgaggaa
tacaaaatatggaaaaagaacaccccttttctttatgatttggtgatgacccatgctctg
gagtggcccagcctaactgcccagtggcttccagatgtaaccagaccagaagggaaagat
ttcagcattcatcgacttgtcctggggacacacacatcggatgaacaaaaccatcttgtt
atagccagtgtgcagctccctaatgatgatgctcagtttgatgcgtcacactacgacagt
gagaaaggagaatttggaggttttggttcagttagtggaaaaattgaaatagaaatcaag
atcaaccatgaaggagaagtaaacagggcccgttatatgccccagaacccttgtatcatc
gcaacaaagactccttccagtgatgttcttgtttttgactatacaaaacatccttctaaa
ccagatccttctggagagtgcaacccagacttgcgtctccgtggacatcagaaggaaggc
tatgggctttcttggaacccaaatctcagtgggcacttacttagtgcttcagatgaccat
accatctgcctgtgggacatcagtgccgttccaaaggagggaaaagtggtagatgcgaag
accatctttacagggcatacggcagtagtagaagatgtttcctggcatctactccatgag
tctctgtttgggtcagttgctgatgatcagaaacttatgatttgggatactcgttcaaac
aatacttccaaaccaagccactcagttgatgctcacactgctgaagtgaactgcctttct
ttcaatccttatagtgagttcattcttgccacaggatcagctgacaagactgttgccttg
tgggatctgagaaatctgaaacttaagttgcattcctttgagtcacataaggatgaaata
ttccaggttcagtggtcacctcacaatgagactattttagcttccagtggtactgatcgc
agactgaatgtctgggatttaagtaaaattggagaggaacaatccccagaagatgcagaa
gacgggccaccagagttgttgtttattcatggtggtcatactgccaagatatctgatttc
tcctggaatcccaatgaaccttgggtgatttgttctgtatcagaagacaatatcatgcaa
gtgtggcaaatggcagagaacatttataatgatgaagaccctgaaggaagcgtggatcca
gaaggacaagggtcctag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Network (4)   
   KEGG NETWORK (4)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (44)   
   KEGG ORTHOLOGY (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (20)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (31)   
   RefSeq(nuc) (3)   
   GenBank (14)   
   EMBL (14)   
3D Structure (37)   
   PDB (37)   
Protein domain (6)   
   Pfam (6)   
All databases (134)   

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