KEGG   Homo sapiens (human): 59350
Entry
59350             CDS       T01001                                 
Symbol
RXFP1, LGR7, RXFPR1
Name
(RefSeq) relaxin receptor 1 isoform 1 precursor
  KO
K04306  relaxin family peptide receptor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04926  Relaxin signaling pathway
Drug target
Serelaxin: D10488
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    59350 (RXFP1)
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    59350 (RXFP1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    59350 (RXFP1)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Relaxin
    59350 (RXFP1)
SSDB
Motif
Pfam: LRR_8 7tm_1 LRR_4 LRR_5 LRR_1 LRR_9 Ldl_recept_a LRRNT LRR_EndoS LRR_LRWD1 LRR_Zer-1
Other DBs
NCBI-GeneID: 59350
NCBI-ProteinID: NP_067647
OMIM: 606654
HGNC: 19718
Ensembl: ENSP00000303248.5
UniProt: Q9HBX9
Structure
Position
4:158521714..158653372
AA seq 757 aa
MTSGSVFFYILIFGKYFSHGGGQDVKCSLGYFPCGNITKCLPQLLHCNGVDDCGNQADED
NCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPECLVGSVPVQCLCQGLELDCDETNLRA
VPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLY
LSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDK
PLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEL
DLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQ
RMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAVTC
FGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFVIGGFDLKFRGEYNKHAQLWM
ESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCVRPGKCRTITVLILIWITGF
IVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYSVAIFLGINLAAFIIIVFSYG
SMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVVKFLSLLQVEIPGT
ITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYRQRKSMDSKGQKTYAPSFIWV
EMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS
NT seq 2274 nt   +upstreamnt  +downstreamnt
atgacatctggttctgtcttcttctacatcttaatttttggaaaatatttttctcatggg
ggtggacaggatgtcaagtgctcccttggctatttcccctgtgggaacatcacaaagtgc
ttgcctcagctcctgcactgtaacggtgtggacgactgcgggaatcaggccgatgaggac
aactgtggagacaacaatggatggtctctgcaatttgacaaatattttgccagttactac
aaaatgacttcccaatatccttttgaggcagaaacacctgaatgtttggtcggttctgtg
ccagtgcaatgtctttgccaaggtctggagcttgactgtgatgaaaccaatttacgagct
gttccatcggtttcttcaaatgtgactgcaatgtcacttcagtggaacttaataagaaag
cttcctcctgattgcttcaagaattatcatgatcttcagaagctgtacctgcaaaacaat
aagattacatccatctccatctatgctttcagaggactgaatagccttactaaactgtat
ctcagtcataacagaataaccttcctgaagccgggtgtttttgaagatcttcacagacta
gaatggctgataattgaagataatcacctcagtcgaatttccccaccaacattttatgga
ctaaattctcttattctcttagtcctgatgaataacgtcctcacccgtttacctgataaa
cctctctgtcaacacatgccaagactacattggctggaccttgaaggcaaccatatccat
aatttaagaaatttgacttttatttcctgcagtaatttaactgttttagtgatgaggaaa
aacaaaattaatcacttaaatgaaaatacttttgcacctctccagaaactggatgaattg
gatttaggaagtaataagattgaaaatcttccaccgcttatattcaaggacctgaaggag
ctgtcacaattgaatctttcctataatccaatccagaaaattcaagcaaaccaatttgat
tatcttgtcaaactcaagtctctcagcctagaagggattgaaatttcaaatatccaacaa
aggatgtttagacctcttatgaatctctctcacatatattttaagaaattccagtactgt
gggtatgcaccacatgttcgcagctgtaaaccaaacactgatggaatttcatctctagag
aatctcttggcaagcattattcagagagtatttgtctgggttgtatctgcagttacctgc
tttggaaacatttttgtcatttgcatgcgaccttatatcaggtctgagaacaagctgtat
gccatgtcaatcatttctctctgctgtgccgactgcttaatgggaatatatttattcgtg
atcggaggctttgacctaaagtttcgtggagaatacaataagcatgcgcagctgtggatg
gagagtactcattgtcagcttgtaggatctttggccattctgtccacagaagtatcagtt
ttactgttaacatttctgacattggaaaaatacatctgcattgtctatccttttagatgt
gtgagacctggaaaatgcagaacaattacagttctgattctcatttggattactggtttt
atagtggctttcattccattgagcaataaggaatttttcaaaaactactatggcaccaat
ggagtatgcttccctcttcattcagaagatacagaaagtattggagcccagatttattca
gtggcaatttttcttggtattaatttggccgcatttatcatcatagttttttcctatgga
agcatgttttatagtgttcatcaaagtgccataacagcaactgaaatacggaatcaagtt
aaaaaagagatgatccttgccaaacgttttttctttatagtatttactgatgcattatgc
tggatacccatttttgtagtgaaatttctttcactgcttcaggtagaaataccaggtacc
ataacctcttgggtagtgatttttattctgcccattaacagtgctttgaacccaattctc
tatactctgaccacaagaccatttaaagaaatgattcatcggttttggtataactacaga
caaagaaaatctatggacagcaaaggtcagaaaacatatgctccatcattcatctgggtg
gaaatgtggccactgcaggagatgccacctgagttaatgaagccggaccttttcacatac
ccctgtgaaatgtcactgatttctcaatcaacgagactcaattcctattcatga

  All links  
Disease (1)   
   OMIM (1)   
Gene (18)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (32)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (30)   
DNA sequence (90)   
   RefSeq(nuc) (36)   
   GenBank (27)   
   EMBL (27)   
3D Structure (3)   
   PDB (3)   
Protein domain (11)   
   Pfam (11)   
All databases (155)   

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