| Entry |
|
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| Gene name |
RHEB, RHEB2
|
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| Definition |
(RefSeq) Ras homolog, mTORC1 binding
|
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| KO |
| K07208 | Ras homolog enriched in brain |
|
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| Organism |
|
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| Pathway |
| hsa04072 | Phospholipase D signaling pathway |
| hsa04919 | Thyroid hormone signaling pathway |
| hsa05163 | Human cytomegalovirus infection |
| hsa05168 | Herpes simplex virus 1 infection |
|
|---|
| Network |
nt06114 PI3K signaling (viruses) nt06166 Human papillomavirus (HPV) nt06167 Human cytomegalovirus (HCMV) nt06168 Herpes simplex virus 1 (HSV-1) |
|---|
| Element |
| N00357 | HPV E6 to MTOR signaling pathway |
| N00388 | HCMV UL38 to MTOR signaling pathway |
| N00582 | IGF-IGF1R-PI3K signaling pathway |
| N00583 | HSV VP11/12 to PI3K signaling pathway |
| N00584 | HSV US3 to MTOR signaling pathway |
|
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04072 Phospholipase D signaling pathway
6009 (RHEB)
04151 PI3K-Akt signaling pathway
6009 (RHEB)
04152 AMPK signaling pathway
6009 (RHEB)
04150 mTOR signaling pathway
6009 (RHEB)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
6009 (RHEB)
09143 Cell growth and death
04218 Cellular senescence
6009 (RHEB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
6009 (RHEB)
04919 Thyroid hormone signaling pathway
6009 (RHEB)
09149 Aging
04211 Longevity regulating pathway
6009 (RHEB)
09159 Environmental adaptation
04714 Thermogenesis
6009 (RHEB)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
6009 (RHEB)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
6009 (RHEB)
05163 Human cytomegalovirus infection
6009 (RHEB)
05165 Human papillomavirus infection
6009 (RHEB)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04031 GTP-binding proteins [BR:hsa04031]
6009 (RHEB)
GTP-binding proteins [BR:hsa04031]
Small (monomeric) G-proteins
Ras Family
Rheb
6009 (RHEB)
 |
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
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| Structure |
PDB: |
|---|
| Position |
7q36.1
|
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| AA seq |
184 aa  
MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD
TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK
KDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSS
CSVM |
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| NT seq |
555 nt  +upstreamnt +downstreamnt
atgccgcagtccaagtcccggaagatcgcgatcctgggctaccggtctgtggggaaatcc
tcattgacgattcaatttgttgaaggccaatttgtggactcctacgatccaaccatagaa
aacacttttacaaagttgatcacagtaaatggacaagaatatcatcttcaacttgtagac
acagccgggcaagatgaatattctatctttcctcagacatactccatagatattaatggc
tatattcttgtgtattctgttacatcaatcaaaagttttgaagtgattaaagttatccat
ggcaaattgttggatatggtggggaaagtacaaatacctattatgttggttgggaataag
aaagacctgcatatggaaagggtgatcagttatgaagaagggaaagctttggcagaatct
tggaatgcagcttttttggaatcttctgctaaagaaaatcagactgctgtggatgttttt
cgaaggataattttggaggcagaaaaaatggacggggcagcttcacaaggcaagtcttca
tgctcggtgatgtga |
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