KEGG   Homo sapiens (human): 6046
Entry
6046              CDS       T01001                                 
Symbol
BRD2, BRD2-IT1, D6S113E, FSH, FSHRG1, FSRG1, NAT, O27.1.1, RING3, RNF3
Name
(RefSeq) bromodomain containing 2
  KO
K08871  bromodomain-containing protein 2
Organism
hsa  Homo sapiens (human)
Drug target
Apabetalone: D11131
Birabresib: D10911
Pelabresib: D12266
Trotabresib: D12006
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    6046 (BRD2)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    6046 (BRD2)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  BRD family [OT]
   6046 (BRD2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Chromatin remodeling factors
   Other chromatin remodeling factors
    6046 (BRD2)
SSDB
Motif
Pfam: Bromodomain BET Sigma70_ner DUF6779
Other DBs
NCBI-GeneID: 6046
NCBI-ProteinID: NP_001106653
OMIM: 601540
HGNC: 1103
Ensembl: ENSG00000204256
UniProt: P25440
Structure
Position
6:32968594..32981505
AA seq 801 aa
MLQNVTPHNKLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLTPAN
PPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQP
MDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASM
PQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVSSVSHTALYTPPPEIPTTVLNI
PHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPA
SPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKEL
LSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRL
MFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSES
SSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQG
PISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSGGGSAAL
GPSGFGPSGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGE
KLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKPYTIKKP
VGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKANEKTESSSAQQVAVSRLSASSSS
SDSSSSSSSSSSSDTSDSDSG
NT seq 2406 nt   +upstreamnt  +downstreamnt
atgctgcaaaacgtgactccccacaataagctccctggggaagggaatgcagggttgctg
gggctgggcccagaagcagcagcaccagggaagaggattcgaaaaccctctctcttgtat
gagggctttgagagccccacaatggcttcggtgcctgctttgcaacttacccctgccaac
ccaccacccccggaggtgtccaatcccaaaaagccaggacgagttaccaaccagctgcaa
tacctacacaaggtagtgatgaaggctctgtggaaacatcagttcgcatggccattccgg
cagcctgtggatgctgtcaaactgggtctaccggattatcacaaaattataaaacagcct
atggacatgggtactattaagaggagacttgaaaacaattattattgggctgcttcagag
tgtatgcaagattttaataccatgttcaccaactgttacatttacaacaagcccactgat
gatattgtcctaatggcacaaacgctggaaaagatattcctacagaaggttgcatcaatg
ccacaagaagaacaagagctggtagtgaccatccctaagaacagccacaagaagggggcc
aagttggcagcgctccagggcagtgttaccagtgcccatcaggtgcctgccgtctcttct
gtgtcacacacagccctgtatactcctccacctgagatacctaccactgtcctcaacatt
ccccacccatcagtcatttcctctccacttctcaagtccttgcactctgctggacccccg
ctccttgctgttactgcagctcctccagcccagccccttgccaagaaaaaaggcgtaaag
cggaaagcagatactaccacccctacacctacagccatcttggctcctggttctccagct
agccctcctgggagtcttgagcctaaggcagcacggcttccccctatgcgtagagagagt
ggtcgccccatcaagcccccacgcaaagacttgcctgactctcagcaacaacaccagagc
tctaagaaaggaaagctttcagaacagttaaaacattgcaatggcattttgaaggagtta
ctctctaagaagcatgctgcctatgcttggcctttctataaaccagtggatgcttctgca
cttggcctgcatgactaccatgacatcattaagcaccccatggacctcagcactgtcaag
cggaagatggagaaccgtgattaccgggatgcacaggagtttgctgctgatgtacggctt
atgttctccaactgctataagtacaatcccccagatcacgatgttgtggcaatggcacga
aagctacaggatgtatttgagttccgttatgccaagatgccagatgaaccactagaacca
gggcctttaccagtctctactgccatgccccctggcttggccaaatcgtcttcagagtcc
tccagtgaggaaagtagcagtgagagctcctctgaggaagaggaggaggaagatgaggag
gacgaggaggaagaagagagtgaaagctcagactcagaggaagaaagggctcatcgctta
gcagaactacaggaacagcttcgggcagtacatgaacaactggctgctctgtcccagggt
ccaatatccaagcccaagaggaaaagagagaaaaaagagaaaaagaagaaacggaaggca
gagaagcatcgaggccgagctggggccgatgaagatgacaaggggcctagggcaccccgc
ccacctcaacctaagaagtccaagaaagcaagtggcagtgggggtggcagtgctgcttta
ggcccttctggctttggaccttctggaggaagtggcaccaagctccccaaaaaggccaca
aagacagccccacctgccctgcctacaggttatgattcagaggaggaggaagagagcagg
cccatgagttacgatgagaagcggcagctgagcctggacatcaacaaattacctggggag
aagctgggccgagttgtgcatataatccaagccagggagccctctttacgtgattcaaac
ccagaagagattgagattgattttgaaacactcaagccatccacacttagagagcttgag
cgctatgtcctttcctgcctacgtaagaaaccccggaagccctacaccattaagaagcct
gtgggaaagacaaaggaggaactggctttggagaaaaagcgggaattagaaaagcggtta
caagatgtcagcggacagctcaattctactaaaaagccccccaagaaagcgaatgagaaa
acagagtcatcctctgcacagcaagtagcagtgtcacgccttagcgcttccagctccagc
tcagattccagctcctcctcttcctcgtcgtcgtcttcagacaccagtgattcagactca
ggctaa

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Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Drug (4)   
   KEGG DRUG (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (32)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
   PHAROS (1)   
Protein sequence (19)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (17)   
DNA sequence (64)   
   RefSeq(nuc) (18)   
   GenBank (23)   
   EMBL (23)   
3D Structure (165)   
   PDB (165)   
Protein domain (4)   
   Pfam (4)   
All databases (293)   

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