KEGG   Homo sapiens (human): 643847
Entry
643847            CDS       T01001                                 

Gene name
PGA4
Definition
(RefSeq) pepsinogen A4
  KO
K06002  pepsin A [EC:3.4.23.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04974  Protein digestion and absorption
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    643847 (PGA4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    643847 (PGA4)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.23  Aspartic endopeptidases
    3.4.23.1  pepsin A
     643847 (PGA4)
Peptidases and inhibitors [BR:hsa01002]
 Aspartic peptidases
  Family A1: pepsin family
   643847 (PGA4)
SSDB
Motif
Pfam: Asp TAXi_N A1_Propeptide Asp_protease_2
Other DBs
NCBI-GeneID: 643847
NCBI-ProteinID: NP_001073276
OMIM: 169720
HGNC: 8886
Ensembl: ENSG00000229183
Vega: OTTHUMG00000168073
Pharos: P0DJD7(Tbio)
UniProt: P0DJD7 A0A1S5UZ02 B7Z719
Structure
PDB: 
1QRP 1PSO 1PSN 1FLH 3UTL

Position
11q12.2
AA seq 388 aa
MKWLLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAP
TLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNP
EDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFD
GILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQSGSVVIFGGIDSSYYTGS
LNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGAS
ENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSEGSCISGFQGMNLPTESGEL
WILGDVFIRQYFTVFDRANNQVGLAPVA
NT seq 1167 nt   +upstreamnt  +downstreamnt
atgaagtggctgctgctgctgggtctggtggcgctctctgagtgcatcatgtacaaggtc
cccctcatcagaaagaagtccttgaggcgcaccctgtccgagcgtggcctgctgaaggac
ttcctgaagaagcacaacctcaacccagccagaaagtacttcccccagtgggaggctccc
accctggtagatgaacagcccctggagaactacctggatatggagtacttcggcactatc
ggcatcggaactcctgcccaggatttcaccgtcgtctttgacaccggctcctccaacctg
tgggtgccctcagtctactgctccagtcttgcctgcaccaaccacaaccgcttcaaccct
gaggattcttccacctaccagtccaccagcgagacagtctccatcacctacggcaccggc
agcatgacaggcatcctcggatacgacactgtccaggttggaggcatctctgacaccaat
cagatcttcggcctgagcgagacggaacctggctccttcctgtattatgctcccttcgat
ggcatcctggggctggcctaccccagcatttcctcctccggggccacacccgtctttgac
aacatctggaaccagggcctggtttctcaggacctcttctctgtctacctcagcgccgat
gaccagagtggcagcgtggtgatctttggtggcattgactcttcttactacactggaagt
ctgaactgggtgcctgttaccgtcgagggttactggcagatcaccgtggacagcatcacc
atgaacggagaggccatcgcctgcgctgagggctgccaggccattgttgacaccggcacc
tctctgctgaccggcccaaccagccccattgccaacatccagagcgacatcggagccagc
gagaactcagatggcgacatggtggtcagctgctcagccatcagcagcctgcccgacatc
gtcttcaccatcaatggagtccagtaccccgtgccacccagtgcctacatcctgcagagc
gaggggagctgcatcagtggcttccagggcatgaacctccccaccgaatctggagagctt
tggatcctgggtgatgtcttcatccgccagtactttaccgtcttcgacagggcaaacaac
caggtcggcctggcccccgtggcttaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
Protein domain (4)   
   Pfam (4)   
All databases (45)   

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