KEGG   Homo sapiens (human): 643847Help
Entry
643847            CDS       T01001                                 

Gene name
PGA4
Definition
(RefSeq) pepsinogen A4
  KO
K06002  pepsin A [EC:3.4.23.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04974  Protein digestion and absorption
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    643847 (PGA4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    643847 (PGA4)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.23  Aspartic endopeptidases
    3.4.23.1  pepsin A
     643847 (PGA4)
Peptidases and inhibitors [BR:hsa01002]
 Aspartic peptidases
  Family A1: pepsin family
   643847 (PGA4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Asp TAXi_N A1_Propeptide Asp_protease_2
Motif
Other DBs
NCBI-GeneID: 643847
NCBI-ProteinID: NP_001073276
OMIM: 169720
HGNC: 8886
Ensembl: ENSG00000229183
Vega: OTTHUMG00000168073
Pharos: P0DJD7(Tbio)
UniProt: P0DJD7 A0A1S5UZ02 B7Z719
Structure
PDB: 

Position
11q12.2
AA seq 388 aa AA seqDB search
MKWLLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAP
TLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNP
EDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFD
GILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQSGSVVIFGGIDSSYYTGS
LNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGAS
ENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSEGSCISGFQGMNLPTESGEL
WILGDVFIRQYFTVFDRANNQVGLAPVA
NT seq 1167 nt NT seq  +upstreamnt  +downstreamnt
atgaagtggctgctgctgctgggtctggtggcgctctctgagtgcatcatgtacaaggtc
cccctcatcagaaagaagtccttgaggcgcaccctgtccgagcgtggcctgctgaaggac
ttcctgaagaagcacaacctcaacccagccagaaagtacttcccccagtgggaggctccc
accctggtagatgaacagcccctggagaactacctggatatggagtacttcggcactatc
ggcatcggaactcctgcccaggatttcaccgtcgtctttgacaccggctcctccaacctg
tgggtgccctcagtctactgctccagtcttgcctgcaccaaccacaaccgcttcaaccct
gaggattcttccacctaccagtccaccagcgagacagtctccatcacctacggcaccggc
agcatgacaggcatcctcggatacgacactgtccaggttggaggcatctctgacaccaat
cagatcttcggcctgagcgagacggaacctggctccttcctgtattatgctcccttcgat
ggcatcctggggctggcctaccccagcatttcctcctccggggccacacccgtctttgac
aacatctggaaccagggcctggtttctcaggacctcttctctgtctacctcagcgccgat
gaccagagtggcagcgtggtgatctttggtggcattgactcttcttactacactggaagt
ctgaactgggtgcctgttaccgtcgagggttactggcagatcaccgtggacagcatcacc
atgaacggagaggccatcgcctgcgctgagggctgccaggccattgttgacaccggcacc
tctctgctgaccggcccaaccagccccattgccaacatccagagcgacatcggagccagc
gagaactcagatggcgacatggtggtcagctgctcagccatcagcagcctgcccgacatc
gtcttcaccatcaatggagtccagtaccccgtgccacccagtgcctacatcctgcagagc
gaggggagctgcatcagtggcttccagggcatgaacctccccaccgaatctggagagctt
tggatcctgggtgatgtcttcatccgccagtactttaccgtcttcgacagggcaaacaac
caggtcggcctggcccccgtggcttaa

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