KEGG   Homo sapiens (human): 64601
Entry
64601             CDS       T01001                                 
Symbol
VPS16, DYT30, hVPS16
Name
(RefSeq) VPS16 core subunit of CORVET and HOPS complexes
  KO
K20180  vacuolar protein sorting-associated protein 16
Organism
hsa  Homo sapiens (human)
Pathway
hsa04140  Autophagy - animal
hsa04148  Efferocytosis
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06532  Autophagy
  Element
N01300  Tethering of late endosomes and lysosomes
N01301  Salmonella SifA to Tethering of late endosomes and lysosomes
N01721  Autophagosome and lysosome fusion, tethering factor
Disease
H00831  Primary dystonia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    64601 (VPS16)
   04148 Efferocytosis
    64601 (VPS16)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    64601 (VPS16)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    64601 (VPS16)
Membrane trafficking [BR:hsa04131]
 Endosome - Lysosome transport
  Tethering complex
   CORVET complex
    64601 (VPS16)
   Hops complex
    64601 (VPS16)
SSDB
Motif
Pfam: Vps16_N Vps16_C
Other DBs
NCBI-GeneID: 64601
NCBI-ProteinID: NP_072097
OMIM: 608550
HGNC: 14584
Ensembl: ENSG00000215305
UniProt: Q9H269
Structure
Position
20:2840745..2866732
AA seq 839 aa
MDCYTANWNPLGDSAFYRKYELYSMDWDLKEELRDCLVAAAPYGGPIALLRNPWRKEKAA
SVRPVLDIYSASGMPLASLLWKSGPVVSLGWSAEEELLCVQEDGAVLVYGLHGDFRRHFS
MGNEVLQNRVLDARIFHTEFGSGVAILTGAHRFTLSANVGDLKLRRMPEVPGLQSAPSCW
TVLCQDRVAHILLAVGPDLYLLDHAACSAVTPPGLAPGVSSFLQMAVSFTYRHLALFTDT
GYIWMGTASLKEKLCEFNCNIRAPPKQMVWCSRPRSKERAVVVAWERRLMVVGDAPESIQ
FVLDEDSYLVPELDGVRIFSRSTHEFLHEVPAASEEIFKIASMAPGALLLEAQKEYEKES
QKADEYLREIQELGQLTQAVQQCIEAAGHEHQPDMQKSLLRAASFGKCFLDRFPPDSFVH
MCQDLRVLNAVRDYHIGIPLTYSQYKQLTIQVLLDRLVLRRLYPLAIQICEYLRLPEVQG
VSRILAHWACYKVQQKDVSDEDVARAINQKLGDTPGVSYSDIAARAYGCGRTELAIKLLE
YEPRSGEQVPLLLKMKRSKLALSKAIESGDTDLVFTVLLHLKNELNRGDFFMTLRNQPMA
LSLYRQFCKHQELETLKDLYNQDDNHQELGSFHIRASYAAEERIEGRVAALQTAADAFYK
AKNEFAAKATEDQMRLLRLQRRLEDELGGQFLDLSLHDTVTTLILGGHNKRAEQLARDFR
IPDKRLWWLKLTALADLEDWEELEKFSKSKKSPIGYLPFVEICMKQHNKYEAKKYASRVG
PEQKVKALLLVGDVAQAADVAIEHRNEAELSLVLSHCTGATDGATADKIQRARAQAQKK
NT seq 2520 nt   +upstreamnt  +downstreamnt
atggactgctacacggcgaactggaacccactcggggactctgccttttaccggaaatat
gagctgtacagcatggactgggacctgaaggaggaactcagggattgcctggtggctgct
gcaccctatgggggccccattgcactgctgaggaacccctggcggaaggagaaagctgct
agtgtgaggccagtgctcgatatatactctgcttccggcatgcctctggccagcctgctg
tggaagagtggacccgtggtgtccctgggctggtcagctgaggaggagctgctctgtgtg
caggaagatggtgctgtactggtttatgggcttcatggtgacttccggagacacttcagc
atgggcaatgaagtgctccagaaccgggttctggatgcccggatctttcacactgagttt
ggttccggagtggccatcctcacaggggcccaccgcttcaccctcagtgccaatgtgggt
gacctcaaactccgccggatgccagaggtgccaggtctgcaaagtgcaccctcctgctgg
actgtgctgtgccaggaccgagtggcacacattcttctggctgtggggcctgacctttac
ctcttggaccatgcagcctgctccgcagtgacgccccctggcctggccccaggagtaagc
agcttcctacagatggctgtctccttcacctaccgacacctggcactcttcacagacaca
ggctacatctggatggggacagcatcactcaaggagaagctatgtgagttcaactgcaac
atccgggcacctccaaagcagatggtctggtgcagccgtcctcgtagcaaggagagggcc
gtggtggtggcctgggaaaggcggctgatggtggtgggcgatgcacccgagagcatccag
tttgtgctggatgaggactcctacctggtgcctgagctcgatggggtccgcatcttctcc
cgcagcacccacgagttcctgcatgaggttccagcggccagcgaggaaatcttcaaaatt
gcctcaatggcccccggggcgctgctcctggaggctcagaaggagtatgagaaagagagc
cagaaggcggacgagtacctgcgggagatccaggagctgggccagctgacccaggccgtg
cagcagtgcattgaggctgcaggacatgagcaccagccagacatgcagaagagtctgctc
agggccgcctccttcggaaagtgtttcctggacagatttccacccgacagcttcgtgcac
atgtgtcaggacctgcgtgtgctcaatgctgttcgggactatcacatcgggatcccgctc
acctatagccaatataagcagctcaccatccaggtgctgctggacaggctcgtgttgcgg
agactttaccccctggccatccagatatgcgagtacttgcgccttcctgaagtacagggc
gtcagcaggatcctggcccactgggcctgctacaaggtgcaacagaaggatgtctcagat
gaggatgtggctcgagccattaaccagaagctgggggacacgcctggtgtctcttactcc
gacattgctgcacgagcctatggttgtggccgcacggagctggccatcaagctgctggag
tatgagccacgctcaggggagcaggtaccccttctcctaaagatgaagaggagcaaactg
gcactaagcaaggccatcgagagcggggacactgacctggtgttcacggtgttgctgcac
ctgaagaacgagctgaaccgaggagattttttcatgacccttcggaatcagcccatggcc
ctcagtttgtaccgacagttctgtaagcatcaggagctagagacgctgaaggacctttac
aatcaggatgacaatcaccaggaattgggcagcttccacatccgagccagctatgctgca
gaagagcgtattgaggggcgagtagcagctctgcagacagccgccgatgccttctacaag
gccaagaatgagtttgcagccaaggctacagaggatcaaatgcggctcctacggctgcag
cggcgcctagaagacgagctggggggccagttcctagacctgtctctacatgacacagtt
accaccctcattcttggcggtcacaacaagcgtgcagagcagctggcacgtgacttccgc
atccctgacaagaggctctggtggctgaagctgactgccctggcagatttggaagattgg
gaagagctagagaagttttccaagagcaagaaatcacccattggctacctgccttttgtg
gagatctgcatgaaacaacataacaaatacgaagccaagaagtatgcttcccgcgtgggt
cccgagcagaaggtcaaggctttgcttcttgttggcgatgtggctcaggctgcagatgtg
gccatcgaacaccggaatgaggctgagctgagcctcgtattgtcccactgcacgggagcc
acagatggggccacagctgacaagattcaacgggccagggcacaagcccagaagaagtga

  All links  
Disease (2)   
   OMIM (2)   
Gene (17)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (31)   
   RefSeq(nuc) (3)   
   GenBank (14)   
   EMBL (14)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (2)   
All databases (57)   

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