KEGG   Homo sapiens (human): 64780Help
Entry
64780             CDS       T01001                                 

Gene name
MICAL1, MICAL, MICAL-1, NICAL
Definition
(RefSeq) microtubule associated monooxygenase, calponin and LIM domain containing 1
  KO
K19947  F-actin monooxygenase [EC:1.14.13.225]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    64780 (MICAL1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.225  F-actin monooxygenase
     64780 (MICAL1)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    64780 (MICAL1)
 Protein recycling
  Rab GTPases and associated proteins
   Others
    64780 (MICAL1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DUF3585 CH FAD_binding_3 LIM Pyr_redox_2 DAO FAD_binding_2 Pyr_redox_3 HI0933_like NAD_binding_7 Pyr_redox CAMSAP_CH NAD_binding_8 Lycopene_cycl FlhC GIDA FAD_oxidored ThiF Thi4
Motif
Other DBs
NCBI-GeneID: 64780
NCBI-ProteinID: NP_073602
OMIM: 607129
HGNC: 20619
Ensembl: ENSG00000135596
Vega: OTTHUMG00000015350
Pharos: Q8TDZ2(Tbio)
UniProt: Q8TDZ2
Structure
PDB: 

Position
6q21
AA seq 1067 aa AA seqDB search
MASPTSTNPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSA
KSLWTKLDKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFS
RHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVT
FTGLQPPPRKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGI
TANFVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKK
QCLLRLGVLRQDWPDTNRLLGSANVVPEALQRFTRAAADFATHGKLGKLEFAQDAHGQPD
VSAFDFTSMMRAESSARVQEKHGARLLLGLVGDCLVEPFWPLGTGVARGFLAAFDAAWMV
KRWAEGAESLEVLAERESLYQLLSQTSPENMHRNVAQYGLDPATRYPNLNLRAVTPNQVR
DLYDVLAKEPVQRNNDKTDTGMPATGSAGTQEELLRWCQEQTAGYPGVHVSDLSSSWADG
LALCALVYRLQPGLLEPSELQGLGALEATAWALKVAENELGITPVVSAQAVVAGSDPLGL
IAYLSHFHSAFKSMAHSPGPVSQASPGTSSAVLFLSKLQRTLQRSRAKENAEDAGGKKLR
LEMEAETPSTEVPPDPEPGVPLTPPSQHQEAGAGDLCALCGEHLYVLERLCVNGHFFHRS
CFRCHTCEATLWPGGYEQHPGDGHFYCLQHLPQTDHKAEGSDRGPESPELPTPSENSMPP
GLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQRLSSLNLTPDPEMEPPPKPPRSCSAL
ARHALESSFVGWGLPVQSPQALVAMEKEEKESPFSSEEEEEDVPLDSDVEQALQTFAKTS
GTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIEAALRELEAEGVKLELALRRQS
SSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMITVQELNLEEKQWQLDQELRGYMNREEN
LKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRLSELALGTGAQG
NT seq 3204 nt NT seq  +upstreamnt  +downstreamnt
atggcttcacctacctccaccaacccagcgcatgcccactttgagagcttcctgcaggcc
cagctgtgccaggacgtgctgagcagcttccaggagctgtgtggggccctggggctggaa
cccggtggggggctgccccagtaccacaagatcaaggaccagctcaactactggagcgcc
aagtcactgtggaccaagctggacaagcgagcaggccagcctgtctaccagcagggccgg
gcctgcaccagcaccaagtgcctggtggtgggtgctggaccttgcgggctgcgggtcgct
gtggagctggcgctgctgggggcccgagtggtgctggtggaaaagcgcaccaagttctct
cgccacaacgtgctccacctctggcccttcaccatccacgacctgcgggcactcggtgct
aagaagttctacgggcgcttctgcaccggcaccctggaccacatcagcatcaggcagctc
cagctgcttctgctgaaggtagcattgctgctgggggtggaaattcactggggtgtcact
ttcactggcctccagccccctcctaggaaggggagtggctggcgtgcccagctccaaccc
aacccccctgcccagctggccaactatgaatttgacgtccttatctcggctgcaggaggt
aaattcgtccctgaaggcttcaaagttcgagaaatgcgaggcaaactggccattggcatc
acagccaactttgtgaatggacgcaccgtggaggagacacaggtgccggagatcagtggt
gtagccaggatctacaaccagagcttcttccagagccttctcaaagccacaggcattgat
ctggagaacattgtgtactacaaggacgacacccactactttgtgatgacagccaagaag
cagtgcctgctgcggctgggggtgctgcgccaggactggccagacaccaatcggctgctg
ggcagtgccaatgtggtgcccgaggctctgcagcgctttacccgggcagctgctgacttt
gccacccatggcaagctcgggaaactagagtttgcccaggatgcccatgggcagcctgat
gtctctgcctttgacttcacgagcatgatgcgggcagagagttctgctcgtgtgcaagag
aagcatggcgcccgcctgctgctgggactggtgggggactgcctggtggagcccttctgg
cccctgggcactggagtggcacggggcttcctggcagcctttgatgcagcctggatggtg
aagcggtgggcagagggcgctgagtccctagaggtgttggctgagcgtgagagcctgtac
cagcttctgtcacagacatccccagaaaacatgcatcgcaatgtggcccagtatgggctg
gacccagccacccgctaccccaacctgaacctccgggcagtgacccccaatcaggtacga
gacctgtatgatgtgctagccaaggagcctgtgcagaggaacaacgacaagacagataca
gggatgccagccaccgggtcggcaggcacccaggaggagctgctacgctggtgccaggag
cagacagctgggtacccgggagtccacgtctccgatttgtcttcctcctgggctgatggg
ctagctctgtgtgccctggtgtaccggctgcagcctggcctgctggaaccctcagagctg
caggggctgggagctctggaagcaactgcttgggcactaaaggtggcagagaatgagctg
ggcatcacaccggtggtgtctgcacaggccgtggtagcagggagtgacccactgggcctc
attgcctacctcagccacttccacagtgccttcaagagcatggcccacagcccaggccct
gtcagccaggcctccccagggacctccagtgctgtattattccttagtaaacttcagagg
accctgcagcgatcccgggccaaggaaaatgcagaggatgctggtggcaagaagctgcgc
ttggagatggaggccgagaccccaagtactgaggtgccacctgacccagagcctggtgta
cccctgacacccccatcccaacaccaggaggccggtgctggggacctgtgtgcactttgt
ggggaacacctctatgtcctggaacgcctctgtgtcaacggccatttcttccaccggagc
tgcttccgctgccatacctgtgaggccacactgtggccaggtggctacgagcagcaccca
ggagatggacatttctactgcctccagcacctgccccagacagaccacaaagcggaaggc
agcgatagaggccctgagagtccggagctccccacaccaagtgagaatagcatgccacca
ggcctctcaactcccacagcctcgcaggagggggccggtcctgttccagatcccagccag
cccacccgtcggcagatccgcctctccagcccggagcgccagcggttgtcctcccttaac
cttacccctgacccggaaatggagcctccacccaagcctccccgcagctgctccgccttg
gcccgccacgccctggagagcagctttgtgggctggggcctgccagtccagagccctcaa
gctcttgtggccatggagaaggaggaaaaagagagtcccttctccagtgaagaggaagaa
gaagatgtgcctttggactcagatgtggaacaggccctgcagacctttgccaagacctca
ggcaccatgaataactacccaacatggcgtcggactctgctgcgccgtgcgaaggaggag
gagatgaagaggttctgcaaggcccagaccatccaacggcgactaaatgagattgaggct
gccttgagggagctagaggccgagggcgtgaagctggagctggccttgaggcgccagagc
agttccccagaacagcaaaagaaactatgggtaggacagctgctacagctcgttgacaag
aaaaacagcctggtggctgaggaggccgagctcatgatcacggtgcaggaattgaatctg
gaggagaaacagtggcagctggaccaggagctacgaggctacatgaaccgggaagaaaac
ctaaagacagctgctgatcggcaggctgaggaccaggtcctgaggaagctggtggatttg
gtcaaccagagagatgccctcatccgcttccaggaggagcgcaggctcagcgagctggcc
ttggggacaggggcccagggctag

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