KEGG   Homo sapiens (human): 6500Help
Entry
6500              CDS       T01001                                 

Gene name
SKP1, EMC19, OCP-II, OCP2, SKP1A, TCEB1L, p19A
Definition
(RefSeq) S-phase kinase associated protein 1
  KO
K03094  S-phase kinase-associated protein 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
hsa04114  Oocyte meiosis
hsa04120  Ubiquitin mediated proteolysis
hsa04141  Protein processing in endoplasmic reticulum
hsa04310  Wnt signaling pathway
hsa04350  TGF-beta signaling pathway
hsa04710  Circadian rhythm
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06123  TNF signaling (viruses and bacteria)
nt06130  Cell cycle (viruses)
nt06165  Epstein-Barr virus (EBV)
nt06166  Human papillomavirus (HPV)
nt06230  Cell cycle G1/S
nt06261  Gastric cancer
nt06267  Small cell lung cancer
nt06272  Prostate cancer
  Element
N00091  p27-Cell cycle G1/S
N00092  Amplified MYC to p27-cell cycle G1/S
N00942  Shigella OspG to TNF-NFKB signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    6500 (SKP1)
   04120 Ubiquitin mediated proteolysis
    6500 (SKP1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    6500 (SKP1)
   04350 TGF-beta signaling pathway
    6500 (SKP1)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    6500 (SKP1)
   04114 Oocyte meiosis
    6500 (SKP1)
 09150 Organismal Systems
  09159 Environmental adaptation
   04710 Circadian rhythm
    6500 (SKP1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    6500 (SKP1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    6500 (SKP1)
   05131 Shigellosis
    6500 (SKP1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    6500 (SKP1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    6500 (SKP1)
   03036 Chromosome and associated proteins [BR:hsa03036]
    6500 (SKP1)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   SCF complex
    Adaptor protein
     6500 (SKP1)
   Cul7 complex
     6500 (SKP1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   Kinetochore proteins
    CBF3 complex
     6500 (SKP1)
  Centrosome formation and ciliogenesis proteins
   Centrosome duplication proteins
    Other centrosome duplication proteins
     6500 (SKP1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Skp1_POZ Skp1
Motif
Other DBs
NCBI-GeneID: 6500
NCBI-ProteinID: NP_733779
OMIM: 601434
HGNC: 10899
Ensembl: ENSG00000113558
Vega: OTTHUMG00000129117
Pharos: P63208(Tbio)
UniProt: P63208
Structure
PDB: 

Position
5q31.1
AA seq 163 aa AA seqDB search
MPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQ
WCTHHKDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTC
KTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK
NT seq 492 nt NT seq  +upstreamnt  +downstreamnt
atgccttcaattaagttgcagagttctgatggagagatatttgaagttgatgtggaaatt
gccaaacaatctgtgactattaagaccatgttggaagatttgggaatggatgatgaagga
gatgatgacccagttcctctaccaaatgtgaatgcagcaatattaaaaaaggtcattcag
tggtgcacccaccacaaggatgaccctcctcctcctgaagatgatgagaacaaagaaaag
cgaacagatgatatccctgtttgggaccaagaattcctgaaagttgaccaaggaacactt
tttgaactcattctggctgcaaactacttagacatcaaaggtttgcttgatgttacatgc
aagactgttgccaatatgatcaaggggaaaactcctgaggagattcgcaagaccttcaat
atcaaaaatgactttactgaagaggaggaagcccaggtacgcaaagagaaccagtggtgt
gaagagaagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (11)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (139)   
   KEGG ORTHOLOGY (1)   
   RefGene (100)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (31)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (28)   
   RefSeq(nuc) (2)   
   GenBank (13)   
   EMBL (13)   
Protein domain (2)   
   Pfam (2)   
All databases (192)   

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