KEGG   Homo sapiens (human): 6523
Entry
6523              CDS       T01001                                 

Symbol
SLC5A1, D22S675, NAGT, SGLT1
Name
(RefSeq) solute carrier family 5 member 1
  KO
K14158  solute carrier family 5 (sodium/glucose cotransporter), member 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04973  Carbohydrate digestion and absorption
hsa04976  Bile secretion
hsa04978  Mineral absorption
Disease
H01261  Congenital glucose-galactose malabsorption
Drug target
Sotagliflozin: D10669
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    6523 (SLC5A1)
   04973 Carbohydrate digestion and absorption
    6523 (SLC5A1)
   04978 Mineral absorption
    6523 (SLC5A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    6523 (SLC5A1)
   04147 Exosome [BR:hsa04147]
    6523 (SLC5A1)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC5: Sodium glucose cotransporter
   6523 (SLC5A1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   6523 (SLC5A1)
SSDB
Motif
Pfam: SSF
Other DBs
NCBI-GeneID: 6523
NCBI-ProteinID: NP_000334
OMIM: 182380
HGNC: 11036
Ensembl: ENSG00000100170
Vega: OTTHUMG00000030768
Pharos: P13866(Tchem)
UniProt: P13866
Position
22q12.3
AA seq 664 aa
MDSSTWSPKTTAVTRPVETHELIRNAADISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFL
AGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFVPIY
IKAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNLYLA
IFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAI
PTIVSDGNTTFQEKCYTPRADSFHIFRDPLTGDLPWPGFIFGMSILTLWYWCTDQVIVQR
CLSAKNMSHVKGGCILCGYLKLMPMFIMVMPGMISRILYTEKIACVVPSECEKYCGTKVG
CTNIAYPTLVVELMPNGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEK
ELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRV
NEPGAFWGLILGLLIGISRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFAISFIT
IVVISLLTKPIPDVHLYRLCWSLRNSKEERIDLDAEEENIQEGPKETIEIETQVPEKKKG
IFRRAYDLFCGLEQHGAPKMTEEEEKAMKMKMTDTSEKPLWRTVLNVNGIILVTVAVFCH
AYFA
NT seq 1995 nt   +upstreamnt  +downstreamnt
atggacagtagcacctggagccccaagaccaccgcggtcacccggcctgttgagacccac
gagctcattcgcaatgcagccgatatctccatcatcgttatctacttcgtggtagtgatg
gccgtcggactgtgggctatgttttccaccaatcgtgggactgttggaggcttcttcctg
gcaggccgaagtatggtgtggtggccgattggagcctccctctttgctagtaacattgga
agtggccactttgtggggctggccgggactggggcagcttcaggcatcgccattggaggc
tttgaatggaatgccctggttttggtggttgtgctgggctggctgtttgtccccatctat
attaaggctggggtggtgacaatgccagagtacctgaggaagcggtttggaggccagcgg
atccaggtctacctttcccttctgtccctgctgctctacattttcaccaagatctcggca
gacatcttctcgggggccatattcatcaatctggccttaggcctgaatctgtatttagcc
atctttctcttattggcaatcactgccctttacacaattacagggggcctggcggcggtg
atttacacggacaccttgcagacggtgatcatgctggtggggtctttaatcctgactggg
tttgcttttcacgaagtgggaggctatgacgccttcatggaaaagtacatgaaagccatt
ccaaccatagtgtctgatggcaacaccacctttcaggaaaaatgctacactccaagggcc
gactccttccacatcttccgagatcccctcacgggagacctcccatggcctgggttcatc
tttgggatgtccatccttaccttgtggtactggtgcacagatcaggtcattgtgcagcgc
tgcctctcagccaagaatatgtctcacgtgaagggtggctgcatcctgtgtgggtatcta
aagctgatgcccatgttcatcatggtgatgccaggaatgatcagccgcattctgtacaca
gaaaaaattgcctgtgtcgtcccttcagaatgtgagaaatattgcggtaccaaggttggc
tgtaccaacatcgcctatccaaccttagtggtggagctcatgcccaatggactgcgaggc
ctgatgctatcagtcatgctggcctccctcatgagctccctgacctccatcttcaacagc
gccagcaccctcttcaccatggacatctacgccaaggtccgcaagagagcatctgagaaa
gagctcatgattgccggaaggttgtttatcctggtgctgattggcatcagcatcgcctgg
gtgcccattgtgcagtcagcacaaagtgggcaactcttcgattacatccagtccatcacc
agttacttgggaccacccattgcggctgtcttcctgcttgctattttctggaagagagtc
aatgagccaggagccttttggggactgatcctaggacttctgattgggatttcacgtatg
attactgagtttgcttatggaaccgggagctgcatggagcccagcaactgtcccacgatt
atctgtggggtgcactacttgtactttgccattatcctcttcgccatttctttcatcacc
atcgtggtcatctccctcctcaccaaacccattccggatgtgcatctctaccgtctgtgt
tggagcctgcgcaacagcaaagaggagcgtattgacctggatgcggaagaggagaacatc
caagaaggccctaaggagaccattgaaatagaaacacaagttcctgagaagaaaaaagga
atcttcaggagagcctatgacctattttgtgggctagagcagcacggtgcacccaagatg
actgaggaagaggagaaagccatgaagatgaagatgacggacacctctgagaagcctttg
tggaggacagtgttgaacgtcaatggcatcatcctggtgaccgtggctgtcttttgccat
gcatattttgcctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (25)   
   RefSeq(nuc) (3)   
   GenBank (11)   
   EMBL (11)   
Protein domain (1)   
   Pfam (1)   
All databases (56)   

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