KEGG   Homo sapiens (human): 6554
Entry
6554              CDS       T01001                                 
Symbol
SLC10A1, FHCA2, NTCP
Name
(RefSeq) solute carrier family 10 member 1
  KO
K14341  solute carrier family 10 (sodium/bile acid cotransporter), member 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa03272  Virion - Hepatitis viruses
hsa04976  Bile secretion
hsa05161  Hepatitis B
Disease
H01935  Familial hypercholanemia
Drug target
Maralixibat (DG02832): D10951
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03272 Virion - Hepatitis viruses
    6554 (SLC10A1)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    6554 (SLC10A1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05161 Hepatitis B
    6554 (SLC10A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    6554 (SLC10A1)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC10: Sodium bile salt cotransporter
   6554 (SLC10A1)
SSDB
Motif
Pfam: SBF SBF_like GAPT DUF2427
Other DBs
NCBI-GeneID: 6554
NCBI-ProteinID: NP_003040
OMIM: 182396
HGNC: 10905
Ensembl: ENSG00000100652
UniProt: Q14973 B2RA41
Structure
Position
14:complement(69775416..69797241)
AA seq 349 aa
MEAHNASAPFNFTLPPNFGKRPTDLALSVILVFMLFFIMLSLGCTMEFSKIKAHLWKPKG
LAIALVAQYGIMPLTAFVLGKVFRLKNIEALAILVCGCSPGGNLSNVFSLAMKGDMNLSI
VMTTCSTFCALGMMPLLLYIYSRGIYDGDLKDKVPYKGIVISLVLVLIPCTIGIVLKSKR
PQYMRYVIKGGMIIILLCSVAVTVLSAINVGKSIMFAMTPLLIATSSLMPFIGFLLGYVL
SALFCLNGRCRRTVSMETGCQNVQLCSTILNVAFPPEVIGPLFFFPLLYMIFQLGEGLLL
IAIFWCYEKFKTPKDKTKMIYTAATTEETIPGALGNGTYKGEDCSPCTA
NT seq 1050 nt   +upstreamnt  +downstreamnt
atggaggcccacaacgcgtctgccccattcaacttcaccctgccacccaactttggcaag
cgccccacagacctggcactgagcgtcatcctggtgttcatgttgttcttcatcatgctc
tcgctgggctgcaccatggagttcagcaagatcaaggctcacttatggaagcctaaaggg
ctggccatcgccctggtggcacagtatggcatcatgcccctcacggcctttgtgctgggc
aaggtcttccggctgaagaacattgaggcactggccatcttggtctgtggctgctcacct
ggagggaacctgtccaatgtcttcagtctggccatgaagggggacatgaacctcagcatt
gtgatgaccacctgctccaccttctgtgcccttggcatgatgcctctcctcctgtacatc
tactccagggggatctatgatggggacctgaaggacaaggtgccctataaaggcatcgtg
atatcactggtcctggttctcattccttgcaccatagggatcgtcctcaaatccaaacgg
ccacaatacatgcgctatgtcatcaagggagggatgatcatcattctcttgtgcagtgtg
gccgtcacagttctctctgccatcaatgtggggaagagcatcatgtttgccatgacacca
ctcttgattgccacctcctccctgatgccttttattggctttctgctgggttatgttctc
tctgctctcttctgcctcaatggacggtgcagacgcactgtcagcatggagactggatgc
caaaatgtccaactctgttccaccatcctcaatgtggcctttccacctgaagtcattgga
ccacttttcttctttcccctcctctacatgattttccagcttggagaagggcttctcctc
attgccatattttggtgctatgagaaattcaagactcccaaggataaaacaaaaatgatc
tacacagctgccacaactgaagaaacaattccaggagctctgggaaatggcacctacaaa
ggggaggactgctccccttgcacagcctag

  All links  
Disease (2)   
   OMIM (2)   
Gene (8)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
3D Structure (10)   
   PDB (10)   
Protein domain (4)   
   Pfam (4)   
All databases (47)   

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