KEGG   Homo sapiens (human): 6580
Entry
6580              CDS       T01001                                 

Gene name
SLC22A1, HOCT1, OCT1, oct1_cds
Definition
(RefSeq) solute carrier family 22 member 1
  KO
K08198  MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04976  Bile secretion
hsa05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    6580 (SLC22A1)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    6580 (SLC22A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    6580 (SLC22A1)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC22: Organic cation/anion/zwitterion transporter
   6580 (SLC22A1)
 Major facilitator superfamily (MFS)
  Organic acid transporters
   Organic cation transporter (OCT) family [TC:2.A.1.19]
    6580 (SLC22A1)
SSDB
Motif
Pfam: Sugar_tr MFS_1
Other DBs
NCBI-GeneID: 6580
NCBI-ProteinID: NP_003048
OMIM: 602607
HGNC: 10963
Ensembl: ENSG00000175003
Vega: OTTHUMG00000015947
Pharos: O15245(Tchem)
UniProt: O15245
Position
6q25.3
AA seq 554 aa
MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT
PFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKEN
TIYLKVQTSEPSGT
NT seq 1665 nt   +upstreamnt  +downstreamnt
atgcccaccgtggatgacattctggagcaggttggggagtctggctggttccagaagcaa
gccttcctcatcttatgcctgctgtcggctgcctttgcgcccatctgtgtgggcatcgtc
ttcctgggtttcacacctgaccaccactgccagagtcctggggtggctgagctgagccag
cgctgtggctggagccctgcggaggagctgaactatacagtgccaggcctggggcccgcg
ggcgaggccttccttggccagtgcaggcgctatgaagtggactggaaccagagcgccctc
agctgtgtagaccccctggctagcctggccaccaacaggagccacctgccgctgggtccc
tgccaggatggctgggtgtatgacacgcccggctcttccatcgtcactgagttcaacctg
gtgtgtgctgactcctggaagctggacctctttcagtcctgtttgaatgcgggcttcttg
tttggctctctcggtgttggctactttgcagacaggtttggccgtaagctgtgtctcctg
ggaactgtgctggtcaacgcggtgtcgggcgtgctcatggccttctcgcccaactacatg
tccatgctgctcttccgcctgctgcagggcctggtcagcaagggcaactggatggctggc
tacaccctaatcacagaatttgttggctcgggctccagaagaacggtggcgatcatgtac
cagatggccttcacggtggggctggtggcgcttaccgggctggcctacgccctgcctcac
tggcgctggctgcagctggcagtctccctgcccaccttcctcttcctgctctactactgg
tgtgtgccggagtcccctcggtggctgttatcacaaaaaagaaacactgaagcaataaag
ataatggaccacatcgctcaaaagaatgggaagttgcctcctgctgatttaaagatgctt
tccctcgaagaggatgtcaccgaaaagctgagcccttcatttgcagacctgttccgcacg
ccgcgcctgaggaagcgcaccttcatcctgatgtacctgtggttcacggactctgtgctc
tatcaggggctcatcctgcacatgggcgccaccagcgggaacctctacctggatttcctt
tactccgctctggtcgaaatcccgggggccttcatagccctcatcaccattgaccgcgtg
ggccgcatctaccccatggccatgtcaaatttgttggcgggggcagcctgcctcgtcatg
atttttatctcacctgacctgcactggttaaacatcataatcatgtgtgttggccgaatg
ggaatcaccattgcaatacaaatgatctgcctggtgaatgctgagctgtaccccacattc
gtcaggaacctcggagtgatggtgtgttcctccctgtgtgacataggtgggataatcacc
cccttcatagtcttcaggctgagggaggtctggcaagccttgcccctcattttgtttgcg
gtgttgggcctgcttgccgcgggagtgacgctacttcttccagagaccaagggggtcgct
ttgccagagaccatgaaggacgccgagaaccttgggagaaaagcaaagcccaaagaaaac
acgatttaccttaaggtccaaacctcagaaccctcgggcacctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (18)   
   RefSeq(nuc) (8)   
   GenBank (5)   
   EMBL (5)   
Protein domain (2)   
   Pfam (2)   
All databases (56)   

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