KEGG   Homo sapiens (human): 6595Help
Entry
6595              CDS       T01001                                 

Gene name
SMARCA2, BAF190, BRM, NCBRS, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p, hBRM, hSNF2a
Definition
(RefSeq) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  KO
K11647  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04714  Thermogenesis
hsa05225  Hepatocellular carcinoma
Disease
H01402  Nicolaides-Baraitser syndrome
H01403  Coffin-Siris syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09159 Environmental adaptation
   04714 Thermogenesis
    6595 (SMARCA2)
 09160 Human Diseases
  09162 Cancers: Specific types
   05225 Hepatocellular carcinoma
    6595 (SMARCA2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    6595 (SMARCA2)
   03036 Chromosome and associated proteins [BR:hsa03036]
    6595 (SMARCA2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.4  Acting on acid anhydrides to facilitate cellular and subcellular movement
    3.6.4.-  
     6595 (SMARCA2)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Coactivators
    BAF/PBAF complex
     6595 (SMARCA2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Chromatin remodeling factors
   BAF complex
    6595 (SMARCA2)
   PBAF complex
    6595 (SMARCA2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: SNF2_N Bromodomain HSA Helicase_C SnAC BRK QLQ ResIII DUF2009
Motif
Other DBs
NCBI-GeneID: 6595
NCBI-ProteinID: NP_001276325
OMIM: 600014
HGNC: 11098
Ensembl: ENSG00000080503
Vega: OTTHUMG00000019445
Pharos: P51531(Tbio)
UniProt: P51531 B4DSC8 Q8N9Q1
Structure
PDB: 

Position
9p24.3
AA seq 1590 aa AA seqDB search
MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTM
GSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGY
MSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLH
QLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQ
QQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAA
AVPGPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQE
LENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKR
QTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAV
ATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANL
TNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHT
ETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKI
LLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLI
NGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIV
PLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHIL
AKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLP
TIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPE
KVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPY
MFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMT
IMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADT
VVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQ
AGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDR
RREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDAL
TEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNP
PKLTKQMNAIIDTVINYKDRCNVEKVPSNSQLEIEGNSSGRQLSEVFIQLPSRKELPEYY
ELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFK
SARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNR
GKAKPVVSDFDSDEEQDEREQSEGSGTDDE
NT seq 4773 nt NT seq  +upstreamnt  +downstreamnt
atgtccacgcccacagaccctggtgcgatgccccacccagggccttcgccggggcctggg
ccttcccctgggccaattcttgggcctagtccaggaccaggaccatccccaggttccgtc
cacagcatgatggggccaagtcctggacctccaagtgtctcccatcctatgccgacgatg
gggtccacagacttcccacaggaaggcatgcatcaaatgcataagcccatcgatggtata
catgacaaggggattgtagaagacatccattgtggatccatgaagggcactggtatgcga
ccacctcacccaggcatgggccctccccagagtccaatggatcaacacagccaaggttat
atgtcaccacacccatctccattaggagccccagagcacgtctccagccctatgtctgga
ggaggcccaactccacctcagatgccaccaagccagccgggggccctcatcccaggtgat
ccgcaggccatgagccagcccaacagaggtccctcacctttcagtcctgtccagctgcat
cagcttcgagctcagattttagcttataaaatgctggcccgaggccagcccctccccgaa
acgctgcagcttgcagtccaggggaaaaggacgttgcctggcttgcagcaacaacagcag
cagcaacagcagcagcagcagcagcagcagcagcagcagcagcagcaacagcagccgcag
cagcagccgccgcaaccacagacgcagcaacaacagcagccggcccttgttaactacaac
agaccatctggcccggggccggagctgagcggcccgagcaccccgcagaagctgccggtg
cccgcgcccggcggccggccctcgcccgcgccccccgcagccgcgcagccgcccgcggcc
gcagtgcccgggccctcagtgccgcagccggccccggggcagccctcgcccgtcctccag
ctgcagcagaagcagagccgcatcagccccatccagaaaccgcaaggcctggaccccgtg
gaaattctgcaagagcgggaatacagacttcaggcccgcatagctcataggatacaagaa
ctggaaaatctgcctggctctttgccaccagatttaagaaccaaagcaaccgtggaacta
aaagcacttcggttactcaatttccagcgtcagctgagacaggaggtggtggcctgcatg
cgcagggacacgaccctggagacggctctcaactccaaagcatacaaacggagcaagcgc
cagactctgagagaagctcgcatgaccgagaagctggagaagcagcagaagattgagcag
gagaggaaacgccgtcagaaacaccaggaatacctgaacagtattttgcaacatgcaaaa
gattttaaggaatatcatcggtctgtggccggaaagatccagaagctctccaaagcagtg
gcaacttggcatgccaacactgaaagagagcagaagaaggagacagagcggattgaaaag
gagagaatgcggcgactgatggctgaagatgaggagggttatagaaaactgattgatcaa
aagaaagacaggcgtttagcttaccttttgcagcagaccgatgagtatgtagccaatctg
accaatctggtttgggagcacaagcaagcccaggcagccaaagagaagaagaagaggagg
aggaggaagaagaaggctgaggagaatgcagagggtggggagtctgccctgggaccggat
ggagagcccatagatgagagcagccagatgagtgacctccctgtcaaagtgactcacaca
gaaaccggcaaggttctgttcggaccagaagcacccaaagcaagtcagctggacgcctgg
ctggaaatgaatcctggttatgaagttgcccctagatctgacagtgaagagagtgattct
gattatgaggaagaggatgaggaagaagagtccagtaggcaggaaaccgaagagaaaata
ctcctggatccaaatagcgaagaagtttctgagaaggatgctaagcagatcattgagaca
gctaagcaagacgtggatgatgaatacagcatgcagtacagtgccaggggctcccagtcc
tactacaccgtggctcatgccatctcggagagggtggagaaacagtctgccctcctaatt
aatgggaccctaaagcattaccagctccagggcctggaatggatggtttccctgtataat
aacaacttgaacggaatcttagccgatgaaatggggcttggaaagaccatacagaccatt
gcactcatcacttatctgatggagcacaaaagactcaatggcccctatctcatcattgtt
cccctttcgactctatctaactggacatatgaatttgacaaatgggctccttctgtggtg
aagatttcttacaagggtactcctgccatgcgtcgctcccttgtcccccagctacggagt
ggcaaattcaatgtcctcttgactacttatgagtatattataaaagacaagcacattctt
gcaaagattcggtggaaatacatgatagtggacgaaggccaccgaatgaagaatcaccac
tgcaagctgactcaggtcttgaacactcactatgtggcccccagaaggatcctcttgact
gggaccccgctgcagaataagctccctgaactctgggccctcctcaacttcctcctccca
acaatttttaagagctgcagcacatttgaacaatggttcaatgctccatttgccatgact
ggtgaaagggtggacttaaatgaagaagaaactatattgatcatcaggcgtctacataag
gtgttaagaccatttttactaaggagactgaagaaagaagttgaatcccagcttcccgaa
aaagtggaatatgtgatcaagtgtgacatgtcagctctgcagaagattctgtatcgccat
atgcaagccaaggggatccttctcacagatggttctgagaaagataagaaggggaaagga
ggtgctaagacacttatgaacactattatgcagttgagaaaaatctgcaaccacccatat
atgtttcagcacattgaggaatcctttgctgaacacctaggctattcaaatggggtcatc
aatggggctgaactgtatcgggcctcagggaagtttgagctgcttgatcgtattctgcca
aaattgagagcgactaatcaccgagtgctgcttttctgccagatgacatctctcatgacc
atcatggaggattattttgcttttcggaacttcctttacctacgccttgatggcaccacc
aagtctgaagatcgtgctgctttgctgaagaaattcaatgaacctggatcccagtatttc
attttcttgctgagcacaagagctggtggcctgggcttaaatcttcaggcagctgataca
gtggtcatctttgacagcgactggaatcctcatcaggatctgcaggcccaagaccgagct
caccgcatcgggcagcagaacgaggtccgggtactgaggctctgtaccgtgaacagcgtg
gaggaaaagatcctcgcggccgcaaaatacaagctgaacgtggatcagaaagtgatccag
gcgggcatgtttgaccaaaagtcttcaagccacgagcggagggcattcctgcaggccatc
ttggagcatgaggaggaaaatgaggaagaagatgaagtaccggacgatgagactctgaac
caaatgattgctcgacgagaagaagaatttgacctttttatgcggatggacatggaccgg
cggagggaagatgcccggaacccgaaacggaagccccgtttaatggaggaggatgagctg
ccctcctggatcattaaggatgacgctgaagtagaaaggctcacctgtgaagaagaggag
gagaaaatatttgggagggggtcccgccagcgccgtgacgtggactacagtgacgccctc
acggagaagcagtggctaagggccatcgaagacggcaatttggaggaaatggaagaggaa
gtacggcttaagaagcgaaaaagacgaagaaatgtggataaagatcctgcaaaagaagat
gtggaaaaagctaagaagagaagaggccgccctcccgctgagaaactgtcaccaaatccc
cccaaactgacaaagcagatgaacgctatcatcgatactgtgataaactacaaagatagg
tgtaacgtggagaaggtgcccagtaattctcagttggaaatagaaggaaacagttcaggg
cgacagctcagtgaagtcttcattcagttaccttcaaggaaagaattaccagaatactat
gaattaattaggaagccagtggatttcaaaaaaataaaggaaaggattcgtaatcataag
taccggagcctaggcgacctggagaaggatgtcatgcttctctgtcacaacgctcagacg
ttcaacctggagggatcccagatctatgaagactccatcgtcttacagtcagtgtttaag
agtgcccggcagaaaattgccaaagaggaagagagtgaggatgaaagcaatgaagaggag
gaagaggaagatgaagaagagtcagagtccgaggcaaaatcagtcaaggtgaaaattaag
ctcaataaaaaagatgacaaaggccgggacaaagggaaaggcaagaaaaggccaaatcga
ggaaaagccaaacctgtagtgagcgattttgacagcgatgaggagcaggatgaacgtgaa
cagtcagaaggaagtgggacggatgatgagtga

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