KEGG   Homo sapiens (human): 6657
Entry
6657              CDS       T01001                                 
Symbol
SOX2, ANOP3, MCOPS3
Name
(RefSeq) SRY-box transcription factor 2
  KO
K16796  transcription factor SOX2 (SOX group B)
Organism
hsa  Homo sapiens (human)
Pathway
hsa04390  Hippo signaling pathway
hsa04550  Signaling pathways regulating pluripotency of stem cells
Disease
H00544  Septo-optic dysplasia
H02170  Microphthalmia, syndromic
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    6657 (SOX2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    6657 (SOX2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    6657 (SOX2)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   HMG SOX
    6657 (SOX2)
SSDB
Motif
Pfam: SOXp HMG_box HMG_box_2 HMG_WDHD1
Other DBs
NCBI-GeneID: 6657
NCBI-ProteinID: NP_003097
OMIM: 184429
HGNC: 11195
Ensembl: ENSG00000181449
UniProt: P48431 A0A0U3FYV6
Structure
Position
3:181711925..181714436
AA seq 317 aa
MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMA
QENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLM
KKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGY
PQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGSM
GSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRLHMSQHYQS
GPVPGTAINGTLPLSHM
NT seq 954 nt   +upstreamnt  +downstreamnt
atgtacaacatgatggagacggagctgaagccgccgggcccgcagcaaacttcggggggc
ggcggcggcaactccaccgcggcggcggccggcggcaaccagaaaaacagcccggaccgc
gtcaagcggcccatgaatgccttcatggtgtggtcccgcgggcagcggcgcaagatggcc
caggagaaccccaagatgcacaactcggagatcagcaagcgcctgggcgccgagtggaaa
cttttgtcggagacggagaagcggccgttcatcgacgaggctaagcggctgcgagcgctg
cacatgaaggagcacccggattataaataccggccccggcggaaaaccaagacgctcatg
aagaaggataagtacacgctgcccggcgggctgctggcccccggcggcaatagcatggcg
agcggggtcggggtgggcgccggcctgggcgcgggcgtgaaccagcgcatggacagttac
gcgcacatgaacggctggagcaacggcagctacagcatgatgcaggaccagctgggctac
ccgcagcacccgggcctcaatgcgcacggcgcagcgcagatgcagcccatgcaccgctac
gacgtgagcgccctgcagtacaactccatgaccagctcgcagacctacatgaacggctcg
cccacctacagcatgtcctactcgcagcagggcacccctggcatggctcttggctccatg
ggttcggtggtcaagtccgaggccagctccagcccccctgtggttacctcttcctcccac
tccagggcgccctgccaggccggggacctccgggacatgatcagcatgtatctccccggc
gccgaggtgccggaacccgccgcccccagcagacttcacatgtcccagcactaccagagc
ggcccggtgcccggcacggccattaacggcacactgcccctctcacacatgtga

  All links  
Disease (2)   
   OMIM (2)   
Gene (25)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (14)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (27)   
   RefSeq(nuc) (1)   
   GenBank (13)   
   EMBL (13)   
3D Structure (8)   
   PDB (8)   
Protein domain (4)   
   Pfam (4)   
All databases (70)   

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