KEGG   Homo sapiens (human): 6751Help
Entry
6751              CDS       T01001                                 

Gene name
SSTR1, SRIF-2, SS-1-R, SS1-R, SS1R
Definition
(RefSeq) somatostatin receptor 1
  KO
K04217  somatostatin receptor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04935  Growth hormone synthesis, secretion and action
Drug target
Pasireotide (DG00503): D10147 D10497 D10566
Seglitide acetate: D05812
Somatostatin: D07431
Veldoreotide: D11192
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    6751 (SSTR1)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    6751 (SSTR1)
 09150 Organismal Systems
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    6751 (SSTR1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    6751 (SSTR1)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Somatostatin
    6751 (SSTR1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7TM_GPCR_Srv 7tm_4 T2SSM Piezo_RRas_bdg
Motif
Other DBs
NCBI-GeneID: 6751
NCBI-ProteinID: NP_001040
OMIM: 182451
HGNC: 11330
Ensembl: ENSG00000139874
Vega: OTTHUMG00000140249
Pharos: P30872(Tclin)
UniProt: P30872 Q86SW9
Position
14q21.1
AA seq 391 aa AA seqDB search
MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAIL
ISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLL
RHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLG
VWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAIC
LCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQD
DATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKS
RAYSVEDFQPENLESGGVFRNGTCTSRITTL
NT seq 1176 nt NT seq  +upstreamnt  +downstreamnt
atgttccccaatggcaccgcctcctctccttcctcctctcctagccccagcccgggcagc
tgcggcgaaggcggcggcagcaggggccccggggccggcgctgcggacggcatggaggag
ccagggcgaaatgcgtcccagaacgggaccttgagcgagggccagggcagcgccatcctg
atctctttcatctactccgtggtgtgcctggtggggctgtgtgggaactctatggtcatc
tacgtgatcctgcgctatgccaagatgaagacggccaccaacatctacatcctaaatctg
gccattgctgatgagctgctcatgctcagcgtgcccttcctagtcacctccacgttgttg
cgccactggcccttcggtgcgctgctctgccgcctcgtgctcagcgtggacgcggtcaac
atgttcaccagcatctactgtctgactgtgctcagcgtggaccgctacgtggccgtggtg
catcccatcaaggcggcccgctaccgccggcccaccgtggccaaggtagtaaacctgggc
gtgtgggtgctatcgctgctcgtcatcctgcccatcgtggtcttctctcgcaccgcggcc
aacagcgacggcacggtggcttgcaacatgctcatgccagagcccgctcaacgctggctg
gtgggcttcgtgttgtacacatttctcatgggcttcctgctgcccgtgggggctatctgc
ctgtgctacgtgctcatcattgctaagatgcgcatggtggccctcaaggccggctggcag
cagcgcaagcgctcggagcgcaagatcaccttaatggtgatgatggtggtgatggtgttt
gtcatctgctggatgcctttctacgtggtgcagctggtcaacgtgtttgctgagcaggac
gacgccacggtgagtcagctgtcggtcatcctcggctatgccaacagctgcgccaacccc
atcctctatggctttctctcagacaacttcaagcgctctttccaacgcatcctatgcctc
agctggatggacaacgccgcggaggagccggttgactattacgccaccgcgctcaagagc
cgtgcctacagtgtggaagacttccaacctgagaacctggagtccggcggcgtcttccgt
aatggcacctgcacgtcccggatcacgacgctctga

KEGG   Homo sapiens (human): 6752Help
Entry
6752              CDS       T01001                                 

Gene name
SSTR2
Definition
(RefSeq) somatostatin receptor 2
  KO
K04218  somatostatin receptor 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04935  Growth hormone synthesis, secretion and action
hsa04971  Gastric acid secretion
Drug target
Indium (111In) pentetreotide: D02108
Lanreotide: D04666
Lutetium (177Lu) oxodotreotide: D11033
Octreotide (DG00501): D00442 D02250 D05230 D06495 D11204
Pasireotide (DG00503): D10147 D10497 D10566
Seglitide acetate: D05812
Somatostatin: D07431
Vapreotide (DG00502): D06281 D09988
Veldoreotide: D11192
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    6752 (SSTR2)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    6752 (SSTR2)
 09150 Organismal Systems
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    6752 (SSTR2)
  09154 Digestive system
   04971 Gastric acid secretion
    6752 (SSTR2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    6752 (SSTR2)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Somatostatin
    6752 (SSTR2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7TM_GPCR_Srv FtsK_4TM
Motif
Other DBs
NCBI-GeneID: 6752
NCBI-ProteinID: NP_001041
OMIM: 182452
HGNC: 11331
Ensembl: ENSG00000180616
Vega: OTTHUMG00000178343
Pharos: P30874(Tclin)
UniProt: P30874
Position
17q25.1
AA seq 369 aa AA seqDB search
MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCG
NTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMT
VDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIY
AGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGI
RVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVL
TYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTL
LNGDLQTSI
NT seq 1110 nt NT seq  +upstreamnt  +downstreamnt
atggacatggcggatgagccactcaatggaagccacacatggctatccattccatttgac
ctcaatggctctgtggtgtcaaccaacacctcaaaccagacagagccgtactatgacctg
acaagcaatgcagtcctcacattcatctattttgtggtctgcatcattgggttgtgtggc
aacacacttgtcatttatgtcatcctccgctatgccaagatgaagaccatcaccaacatt
tacatcctcaacctggccatcgcagatgagctcttcatgctgggtctgcctttcttggct
atgcaggtggctctggtccactggccctttggcaaggccatttgccgggtggtcatgact
gtggatggcatcaatcagttcaccagcatcttctgcctgacagtcatgagcatcgaccga
tacctggctgtggtccaccccatcaagtcggccaagtggaggagaccccggacggccaag
atgatcaccatggctgtgtggggagtctctctgctggtcatcttgcccatcatgatatat
gctgggctccggagcaaccagtgggggagaagcagctgcaccatcaactggccaggtgaa
tctggggcttggtacacagggttcatcatctacactttcattctggggttcctggtaccc
ctcaccatcatctgtctttgctacctgttcattatcatcaaggtgaagtcctctggaatc
cgagtgggctcctctaagaggaagaagtctgagaagaaggtcacccgaatggtgtccatc
gtggtggctgtcttcatcttctgctggcttcccttctacatattcaacgtttcttccgtc
tccatggccatcagccccaccccagcccttaaaggcatgtttgactttgtggtggtcctc
acctatgctaacagctgtgccaaccctatcctatatgccttcttgtctgacaacttcaag
aagagcttccagaatgtcctctgcttggtcaaggtgagcggcacagatgatggggagcgg
agtgacagtaagcaggacaaatcccggctgaatgagaccacggagacccagaggaccctc
ctcaatggagacctccaaaccagtatctga

KEGG   Homo sapiens (human): 6753Help
Entry
6753              CDS       T01001                                 

Gene name
SSTR3, SS-3-R, SS3-R, SS3R, SSR-28
Definition
(RefSeq) somatostatin receptor 3
  KO
K04219  somatostatin receptor 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04935  Growth hormone synthesis, secretion and action
Drug target
Indium (111In) pentetreotide: D02108
Pasireotide (DG00503): D10147 D10497 D10566
Seglitide acetate: D05812
Somatostatin: D07431
Veldoreotide: D11192
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    6753 (SSTR3)
 09150 Organismal Systems
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    6753 (SSTR3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    6753 (SSTR3)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Somatostatin
    6753 (SSTR3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7TM_GPCR_Srv 7TM_GPCR_Srw 7tm_4 Rab5ip
Motif
Other DBs
NCBI-GeneID: 6753
NCBI-ProteinID: NP_001042
OMIM: 182453
HGNC: 11332
Ensembl: ENSG00000278195
Vega: OTTHUMG00000150537
Pharos: P32745(Tclin)
UniProt: P32745
Position
22q13.1
AA seq 418 aa AA seqDB search
MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL
GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM
AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV
FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV
WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA
LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE
SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
NT seq 1257 nt NT seq  +upstreamnt  +downstreamnt
atggacatgcttcatccatcatcggtgtccacgacctcagaacctgagaatgcctcctcg
gcctggcccccagatgccaccctgggcaacgtgtcggcgggcccaagcccggcagggctg
gccgtcagtggcgttctgatccccctggtctacctggtggtgtgcgtggtgggcctgctg
ggtaactcgctggtcatctatgtggtcctgcggcacacggccagcccttcagtcaccaac
gtctacatcctcaacctggcgctggccgacgagctcttcatgctggggctgcccttcctg
gccgcccagaacgccctgtcctactggcccttcggctccctcatgtgccgcctggtcatg
gcggtggatggcatcaaccagttcaccagcatattctgcctgactgtcatgagcgtggac
cgctacctggccgtggtacatcccacccgctcggcccgctggcgcacagctccggtggcc
cgcacggtcagcgcggctgtgtgggtggcctcagccgtggtggtgctgcccgtggtggtc
ttctcgggagtgccccgcggcatgagcacctgccacatgcagtggcccgagccggcggcg
gcctggcgagccggcttcatcatctacacggccgcactgggcttcttcgggccgctgctg
gtcatctgcctctgctacctgctcatcgtggtgaaggtgcgctcagctgggcgccgggtg
tgggcaccctcgtgccagcggcggcggcgctccgaacgcagggtcacgcgcatggtggtg
gccgtggtggcgctcttcgtgctctgctggatgcccttctacgtgctcaacatcgtcaac
gtggtgtgcccactgcccgaggagcctgccttctttgggctctacttcctggtggtggcg
ctgccctatgccaacagctgtgccaaccccatcctttatggcttcctctcctaccgcttc
aagcagggcttccgcagggtcctgctgcggccctcccgccgtgtgcgcagccaggagccc
actgtggggcccccggagaagactgaggaggaggatgaggaggaggaggatggggaggag
agcagggaggggggcaaggggaaggagatgaacggccgggtcagccagatcacgcagcct
ggcaccagcgggcaggagcggccgcccagcagagtggccagcaaggagcagcagctccta
ccccaagaggcttccactggggagaagtccagcacgatgcgcatcagctacctgtag

KEGG   Homo sapiens (human): 6754Help
Entry
6754              CDS       T01001                                 

Gene name
SSTR4, SS-4-R, SS4-R, SS4R
Definition
(RefSeq) somatostatin receptor 4
  KO
K04220  somatostatin receptor 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
Drug target
Seglitide acetate: D05812
Somatostatin: D07431
Veldoreotide: D11192
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    6754 (SSTR4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    6754 (SSTR4)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Somatostatin
    6754 (SSTR4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7TM_GPCR_Srv 7TM_GPCR_Srw 7tm_4
Motif
Other DBs
NCBI-GeneID: 6754
NCBI-ProteinID: NP_001043
OMIM: 182454
HGNC: 11333
Ensembl: ENSG00000132671
Vega: OTTHUMG00000032054
Pharos: P31391(Tclin)
UniProt: P31391
Position
20p11.21
AA seq 388 aa AA seqDB search
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLV
GLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCR
AVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLP
IAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRA
VALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILS
YANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCM
CPPLPCQQEALQPEPGRKRIPLTRTTTF
NT seq 1167 nt NT seq  +upstreamnt  +downstreamnt
atgagcgccccctcgacgctgccccccgggggcgaggaagggctggggacggcctggccc
tctgcagccaatgccagtagcgctccggcggaggcggaggaggcggtggcggggcccggg
gacgcgcgggcggcgggcatggtcgctatccagtgcatctacgcgctggtgtgcctggtg
gggctggtgggcaacgccctggtcatcttcgtgatccttcgctacgccaagatgaagacg
gctaccaacatctacctgctcaacctggccgtagccgacgagctcttcatgctgagcgtg
cccttcgtggcctcgtcggccgccctgcgccactggcccttcggctccgtgctgtgccgc
gcggtgctcagcgtcgacggcctcaacatgttcaccagcgtcttctgtctcaccgtgctc
agcgtggaccgctacgtggccgtggtgcaccctctgcgcgcggcgacctaccggcggccc
agcgtggccaagctcatcaacctgggcgtgtggctggcatccctgttggtcactctcccc
atcgccatcttcgcagacaccagaccggctcgcggcggccaggccgtggcctgcaacctg
cagtggccacacccggcctggtcggcagtcttcgtggtctacactttcctgctgggcttc
ctgctgcccgtgctggccattggcctgtgctacctgctcatcgtgggcaagatgcgcgcc
gtggccctgcgcgctggctggcagcagcgcaggcgctcggagaagaaaatcaccaggctg
gtgctgatggtcgtggtcgtctttgtgctctgctggatgcctttctacgtggtgcagctg
ctgaacctcttcgtgaccagccttgatgccaccgtcaaccacgtgtcccttatccttagc
tatgccaacagctgcgccaaccccattctctatggcttcctctccgacaacttccgccga
ttcttccagcgggttctctgcctgcgctgctgcctcctggaaggtgctggaggtgctgag
gaggagcccctggactactatgccactgctctcaagagcaaaggtggggcagggtgcatg
tgccccccactcccctgccagcaggaagccctgcaaccagaacccggccgcaagcgcatc
cccctcaccaggaccaccaccttctga

KEGG   Homo sapiens (human): 6755Help
Entry
6755              CDS       T01001                                 

Gene name
SSTR5, SS-5-R
Definition
(RefSeq) somatostatin receptor 5
  KO
K04221  somatostatin receptor 5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04935  Growth hormone synthesis, secretion and action
Drug target
Indium (111In) pentetreotide: D02108
Lanreotide: D04666
Pasireotide (DG00503): D10147 D10497 D10566
Seglitide acetate: D05812
Somatostatin: D07431
Vapreotide (DG00502): D06281 D09988
Veldoreotide: D11192
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    6755 (SSTR5)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    6755 (SSTR5)
 09150 Organismal Systems
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    6755 (SSTR5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    6755 (SSTR5)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Somatostatin
    6755 (SSTR5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7TM_GPCR_Srv 7TM_GPCR_Srw
Motif
Other DBs
NCBI-GeneID: 6755
NCBI-ProteinID: NP_001044
OMIM: 182455
HGNC: 11334
Ensembl: ENSG00000162009
Vega: OTTHUMG00000047842
Pharos: P35346(Tclin)
UniProt: P35346
Position
16p13.3
AA seq 364 aa AA seqDB search
MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTL
VIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDG
VNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADV
QEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRR
RSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCAN
PVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQ
TSKL
NT seq 1095 nt NT seq  +upstreamnt  +downstreamnt
atggagcccctgttcccagcctccacgcccagctggaacgcctcctccccgggggctgcc
tctggaggcggtgacaacaggacgctggtggggccggcgccctcggcaggggcccgggcg
gtgctggtgcccgtgctgtacctgctggtgtgtgcggccgggctgggcgggaacacgctg
gtcatctacgtggtgctgcgcttcgccaagatgaagaccgtcaccaacatctacattctc
aacctggcagtggccgacgtcctgtacatgctggggctgcctttcctggccacgcagaac
gccgcgtccttctggcccttcggccccgtcctgtgccgcctggtcatgacgctggacggc
gtcaaccagttcaccagtgtcttctgcctgacagtcatgagcgtggaccgctacctggca
gtggtgcacccgctgagctcggcccgctggcgccgcccgcgtgtggccaagctggcgagc
gccgcggcctgggtcctgtctctgtgcatgtcgctgccgctcctggtgttcgcggacgtg
caggagggcggtacctgcaacgccagctggccggagcccgtggggctgtggggcgccgtc
ttcatcatctacacggccgtgctgggcttcttcgcgccgctgctggtcatctgcctgtgc
tacctgctcatcgtggtgaaggtgagggcggcgggcgtgcgcgtgggctgcgtgcggcgg
cgctcggagcggaaggtgacgcgcatggtgttggtggtggtgctggtgtttgcgggatgt
tggctgcccttcttcaccgtcaacatcgtcaacctggccgtggcgctgccccaggagccc
gcctccgccggcctctacttcttcgtggtcatcctctcctacgccaacagctgtgccaac
cccgtcctctacggcttcctctctgacaacttccgccagagcttccagaaggttctgtgc
ctccgcaagggctctggtgccaaggacgctgacgccacggagccgcgtccagacaggatc
cggcagcagcaggaggccacgccacccgcgcaccgcgccgcagccaacgggcttatgcag
accagcaagctgtga

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