KEGG   Homo sapiens (human): 676
Entry
676               CDS       T01001                                 
Symbol
BRDT, BRD6, CT9, SPGF21
Name
(RefSeq) bromodomain testis associated
  KO
K11724  bromodomain testis-specific protein
Organism
hsa  Homo sapiens (human)
Disease
H01282  Spermatogenic failure
Drug target
Apabetalone: D11131
Pelabresib: D12266
Repibresib: D13101
Trotabresib: D12006
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    676 (BRDT)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    676 (BRDT)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  BRD family [OT]
   676 (BRDT)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Chromatin remodeling factors
   Other chromatin remodeling factors
    676 (BRDT)
SSDB
Motif
Pfam: Bromodomain BET BRD4_CDT
Other DBs
NCBI-GeneID: 676
NCBI-ProteinID: NP_001229734
OMIM: 602144
HGNC: 1105
Ensembl: ENSG00000137948
UniProt: Q58F21
Structure
Position
1:91949371..92014428
AA seq 947 aa
MSLPSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVK
LQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQ
ALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQQEIPSV
FPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSPTFTEKSV
ALPPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVD
VNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVT
MARMLQDVFETHFSKIPIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERV
KRLAKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRL
KEKSKRNQPKKRKQQFIGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSR
EPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQ
ELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSS
DSSDSESEMFPKFTEVKPNDSPSKENVKKMKNECIPPEGRTGVTQIGYCVQDTTSANTTL
VHQTTPSHVMPPNHHQLAFNYQELEHLQTVKNISPLQILPPSGDSEQLSNGITVMHPSGD
SDTTMLESECQAPVQKDIKIKNADSWKSLGKPVKPSGVMKSSDELFNQFRKAAIEKEVKA
RTQELIRKHLEQNTKELKASQENQRDLGNGLTVESFSNKIQNKCSGEEQKEHQQSSEAQD
KSKLWLLKDRDLARQKEQERRRREAMVGTIDMTLQSDIMTMFENNFD
NT seq 2844 nt   +upstreamnt  +downstreamnt
atgtctctgccaagtcgacaaacagctattattgttaaccctcctccaccagaatatata
aatactaagaaaaatgggcgattgacaaatcaacttcagtatctacaaaaagttgtccta
aaggatttatggaagcatagtttttcatggccctttcaacgtcctgtggatgctgtgaaa
ctacagttgcctgattattataccattataaaaaacccaatggatttaaatacaattaag
aagcgcttggagaataaatattatgcgaaggcttcagaatgtatagaagacttcaataca
atgttctcaaattgttatttatataacaagcctggagatgacattgttcttatggcacaa
gctctagagaagctgtttatgcagaaattatctcagatgccacaagaagagcaagttgtg
ggtgttaaggaaagaatcaagaaaggcactcaacagaatatagctgtttcttctgctaaa
gaaaaatcatcacccagcgcaacagaaaaagtatttaagcagcaagaaattccttctgta
tttcctaagacatctatttctcccttgaacgtggtacagggagcttcagtcaactccagt
tcacaaactgcggcccaagttacaaaaggtgtgaagaggaaagcagatacaacaactcct
gcaacttcagcagttaaagcaagtagtgaattttctccaacattcacagaaaaatcagtg
gcactgccacctataaaagaaaatatgccaaagaatgttttgccagattctcagcaacaa
tataatgttgtgaagactgttaaagtaactgaacaattaaggcactgtagtgagattctt
aaagaaatgcttgcaaagaaacatttttcatatgcatggcccttttataatcctgttgac
gttaatgctttgggactccataactactatgacgttgtcaaaaatccgatggatcttgga
actattaaggagaaaatggataaccaagaatataaggatgcatacaaatttgcggcagat
gttagattaatgttcatgaattgctacaagtacaatcctccagatcacgaagttgtgaca
atggcaagaatgcttcaggatgttttcgaaacgcatttttcaaagatcccgattgaacct
gttgagagtatgcctttatgttacatcaaaacagatatcacagaaaccactggtagagag
aacactaatgaagcctcctctgaagggaactcttctgatgattctgaagatgagcgagtt
aagcgtcttgcaaagcttcaggagcagcttaaagctgtacatcaacagctccaggttttg
tcccaagtacctttccgtaagctaaataaaaagaaagagaagtctaaaaaggaaaagaaa
aaagaaaaggttaataacagcaatgaaaatccaagaaaaatgtgtgagcaaatgaggcta
aaggaaaagtccaagagaaatcagccaaagaaaaggaaacaacagttcattggtctaaaa
tctgaagatgaagataatgctaaacctatgaactatgatgagaaaaggcagttaagtctg
aatataaacaaactccctggagataaacttgggcgagtagttcacataatacaatcaaga
gagccttctctgagcaattccaatcctgatgagatagagatagactttgaaacactgaaa
gcatcaacactaagagaattagaaaaatatgtttcggcatgtctaagaaagagaccatta
aaacctcctgctaagaaaataatgatgtccaaagaagaacttcactcacagaaaaaacag
gaattggaaaagcggttactggatgttaataatcagttaaattctagaaaacgtcaaaca
aaatctgataaaacgcaaccatccaaagctgttgaaaatgtttcccgactgagtgagagc
agcagcagcagcagcagctcatcagagtctgaaagtagcagcagtgacttaagctcttca
gacagcagtgattctgaatcagaaatgttccctaagtttacagaagtaaaaccaaatgat
tctccttctaaagagaatgtaaagaaaatgaagaatgaatgcataccgcctgaaggaaga
acaggcgtcacacagataggatattgtgtgcaagacacaacctctgccaatactaccctt
gttcatcagaccacaccttcacatgtaatgccaccaaatcaccaccaattagcatttaat
tatcaagaattagaacatttacagactgtgaaaaacatttcacctttacaaattctgcct
ccctcaggtgattctgaacagctctcaaatggcataactgtgatgcatccatctggtgat
agtgacacaacgatgttagaatctgaatgtcaagctcctgtacagaaggatataaagatt
aagaatgcagattcatggaaaagtttaggcaaaccagtgaaaccatcaggtgtaatgaaa
tcctcagatgagctcttcaaccaatttagaaaagcagccatagaaaaggaagtaaaagct
cggacacaggaactcatacggaagcatttggaacaaaatacaaaggaactaaaagcatct
caagaaaatcagagggatcttgggaatggattgactgtagaatctttttcaaataaaata
caaaacaagtgctctggagaagagcagaaagaacatcagcagtcatcagaagctcaagat
aaatccaaactctggcttctcaaagaccgtgatttagcaaggcagaaagaacaagagagg
aggaggagagaagcaatggtgggtaccattgatatgacccttcaaagtgacattatgaca
atgtttgaaaacaactttgattaa

  All links  
Disease (2)   
   OMIM (2)   
Gene (28)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (26)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (24)   
DNA sequence (56)   
   RefSeq(nuc) (24)   
   GenBank (16)   
   EMBL (16)   
3D Structure (21)   
   PDB (21)   
Protein domain (3)   
   Pfam (3)   
All databases (136)   

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