KEGG   Homo sapiens (human): 6792
Entry
6792              CDS       T01001                                 

Gene name
CDKL5, CFAP247, EIEE2, ISSX, STK9
Definition
(RefSeq) cyclin dependent kinase like 5
  KO
K08824  cyclin-dependent kinase-like [EC:2.7.11.22]
Organism
hsa  Homo sapiens (human)
Disease
H00606  Early infantile epileptic encephalopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    6792 (CDKL5)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     6792 (CDKL5)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CMGC group
  CDKL family
   6792 (CDKL5)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr RIO1 Pkinase_fungal
Other DBs
NCBI-GeneID: 6792
NCBI-ProteinID: NP_001032420
OMIM: 300203
HGNC: 11411
Ensembl: ENSG00000008086
Vega: OTTHUMG00000021214
Pharos: O76039(Tchem)
UniProt: O76039
Structure
PDB: 
4BGQ

Position
Xp22.13
AA seq 1030 aa
MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRE
LKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLI
KAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSP
ELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYS
NPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQ
RLLDRSPSRSAKRKPYHVESSTLSNRNQAGKSTALQSHHRSNSKDIQNLSVGLPRADEGL
PANESFLNGNLAGASLSPLHTKTYQASSQPGSTSKDLTNNNIPHLLSPKEAKSKTEFDFN
IDPKPSEGPGTKYLKSNSRSQQNRHSFMESSQSKAGTLQPNEKQSRHSYIDTIPQSSRSP
SYRTKAKSHGALSDSKSVSNLSEARAQIAEPSTSRYFPSSCLDLNSPTSPTPTRHSDTRT
LLSPSGRNNRNEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTS
PFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVA
RSSVKETSREGTSSFHTRQKSEGGVYHDPHSDDGTAPKENRHLYNDPVPRRVGSFYRVPS
PRPDNSFHENNVSTRVSSLPSESSSGTNHSKRQPAFDPWKSPENISHSEQLKEKEKQGFF
RSMKKKKKKSQTVPNSDSPDLLTLQKSIHSASTPSSRPKEWRPEKISDLQTQSQPLKSLR
KLLHLSSASNHPASSDPRFQPLTAQQTKNSFSEIRIHPLSQASGGSSNIRQEPAPKGRPA
LQLPDGGCDGRRQRHHSGPQDRRFMLRTTEQQGEYFCCGDPKKPHTPCVPNRALHRPISS
PAPYPVLQVRGTSMCPTLQVRGTDAFSCPTQQSGFSFFVRHVMREALIHRAQVNQAALLT
YHENAALTGK
NT seq 3093 nt   +upstreamnt  +downstreamnt
atgaagattcctaacattggtaatgtgatgaataaatttgagatccttggggttgtaggt
gaaggagcctatggagttgtacttaaatgcagacacaaggaaacacatgaaattgtggcg
atcaagaaattcaaggacagtgaagaaaatgaagaagtcaaagaaacgactttacgagag
cttaaaatgcttcggactctcaagcaggaaaacattgtggagttgaaggaagcatttcgt
cggaggggaaagttgtacttggtgtttgagtatgttgaaaaaaatatgctcgaattgctg
gaagaaatgccaaatggagttccacctgagaaagtaaaaagctacatctatcagctaatc
aaggctattcactggtgccataagaatgatattgtccatcgagatataaaaccagaaaat
ctcttaatcagccacaatgatgtcctaaaactgtgtgactttggttttgctcgtaatctg
tcagaaggcaataatgctaattacacagagtacgttgccaccagatggtatcggtcccca
gaactcttacttggcgctccctatggaaagtccgtggacatgtggtcggtgggctgtatt
cttggggagcttagcgatggacagcctttatttcctggagaaagtgaaattgaccaactt
tttactattcagaaggtgctaggaccacttccatctgagcagatgaagcttttctacagt
aatcctcgcttccatgggctccggtttccagctgttaaccatcctcagtccttggaaaga
agataccttggaattttgaatagtgttctacttgacctaatgaagaatttactgaagttg
gacccagctgacagatacttgacagaacagtgtttgaatcaccctacatttcaaacccag
agacttctggatcgttctccttcaaggtcagcaaaaagaaaaccttaccatgtggaaagc
agcacattgtctaatagaaaccaagccggcaaaagtactgctttgcagtctcaccacaga
tctaacagcaaggacatccagaacctgagtgtaggcctgccccgggctgacgaaggtctc
cctgccaatgaaagcttcctaaatggaaaccttgctggagctagtcttagtccactgcac
accaaaacctaccaagcaagcagccagcctgggtctaccagcaaagatctcaccaacaac
aacataccacaccttcttagcccaaaagaagccaagtcaaaaacagagtttgattttaat
attgacccaaagccttcagaaggcccagggacaaagtacctcaagtcaaacagcagatct
cagcagaaccgccactcattcatggaaagctctcaaagcaaagctgggacactgcagccc
aatgaaaagcagagtcggcatagctatattgacacaattccccagtcctctaggagtccc
tcctacaggaccaaggccaaaagccatggggcactgagtgactccaagtctgtgagcaac
ctttctgaagccagggcccaaattgcggagcccagtaccagtaggtacttcccatctagc
tgcttagacttgaattctcccaccagcccaacccccaccagacacagtgacacgagaact
ttgctcagcccttctggaagaaataaccgaaatgagggaacgctggactcacgtcgaacc
acaaccagacattctaagacgatggaggaattgaagctgccggagcacatggacagtagc
cattcccattcactgtctgcacctcacgaatctttttcttatggactgggctacaccagc
cccttttcttcccagcaacgtcctcataggcattctatgtatgtgacccgtgacaaagtg
agagccaagggcttggatggaagcttgagcatagggcaagggatggcagctagagccaac
agcctgcaactcttgtcaccccagcctggagaacagctccctccagagatgactgtggca
agatcttcggtcaaagagacctccagagaaggcacctcttccttccatacacgccagaag
tctgagggtggagtgtatcatgacccacactctgatgatggcacagcccccaaagaaaat
agacacctatacaatgatcctgtgccaaggagagttggtagcttttacagagtgccatct
ccacgtccagacaattctttccatgaaaataatgtgtcaactagagtttcttctctacca
tcagagagcagttctggaaccaaccactcaaaaagacaaccagcattcgatccatggaaa
agtcctgaaaatattagtcattcagagcaactcaaggaaaaagagaagcaaggatttttc
aggtcaatgaaaaagaaaaagaagaaatctcaaacagtacccaattccgacagccctgat
cttctgacgttgcagaaatccattcattctgctagcactccaagcagcagaccaaaggag
tggcgccccgagaagatctcagatctgcagacccaaagccagccattaaaatcactgcgc
aagttgttacatctctcttcggcctcaaatcacccggcttcctcagatccccgcttccag
cccttaacagctcaacaaaccaaaaattccttctcagaaattcggattcaccccctgagc
caggcctctggcgggagcagcaacatccggcaggaacccgcaccgaagggcaggccagcc
ctccagctgccagacggtggatgtgatggcagaagacagagacaccattctggaccccaa
gatagacgcttcatgttaaggacgacagaacaacaaggagaatacttctgctgtggtgac
ccaaagaagcctcacactccgtgcgtcccaaaccgagcccttcatcgtccaatctccagt
cctgctccctatccagtactccaggtccgaggcacttccatgtgcccgacactccaggtc
cgaggcactgatgctttcagctgcccaacccagcaatccgggttctctttcttcgtgaga
cacgttatgagggaagccctgattcacagggcccaggtaaaccaagctgcgctcctgaca
taccatgagaatgcggcactgacgggcaagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (40)   
   KEGG ORTHOLOGY (1)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (10)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (23)   
   RefSeq(nuc) (3)   
   GenBank (10)   
   EMBL (10)   
Protein domain (4)   
   Pfam (4)   
All databases (80)   

Download RDF
DBGET integrated database retrieval system