KEGG   Homo sapiens (human): 6872
Entry
6872              CDS       T01001                                 
Symbol
TAF1, BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, MRXS33, N-TAF1, NSCL2, OF, P250, TAF(II)250, TAF2A, TAFII-250, TAFII250, XDP
Name
(RefSeq) TATA-box binding protein associated factor 1
  KO
K03125  transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03022  Basal transcription factors
Disease
H00658  X-linked syndromic intellectual developmental disorder
H00831  Primary dystonia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03022 Basal transcription factors
    6872 (TAF1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    6872 (TAF1)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    6872 (TAF1)
   03036 Chromosome and associated proteins [BR:hsa03036]
    6872 (TAF1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.48  histone acetyltransferase
     6872 (TAF1)
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     6872 (TAF1)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  TAF1 family
   6872 (TAF1)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Basal transcription factors
    TFIID
     6872 (TAF1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HATs (histone acetyltransferases)
    6872 (TAF1)
SSDB
Motif
Pfam: DUF3591 Bromodomain TBP-binding zf-CCHC_6 Cac1_C Opi1 Ribosomal_L44 Zn_ribbon_12
Other DBs
NCBI-GeneID: 6872
NCBI-ProteinID: NP_001273003
OMIM: 313650
HGNC: 11535
Ensembl: ENSG00000147133
UniProt: P21675
Structure
Position
X:71366357..71530525
AA seq 1875 aa
MSDTDSDEDSAGGGPFSLAGFLFGNINGAGQLEGESVLDDECKKHLAGLGALGLGSLITE
LTANEELTGTDGALVNDEGWVRSTEDAVDYSDINEVAEDESRRYQQTMGSLQPLCHSDYD
EDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDSITGVSENGEGIILPSIIAPSSLASEK
VDFSSSSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDATKLLPSVTELFPEFRPGKVL
RFLRLFGPGKNVPSVWRSARRKRKKKHRELIQEEQIQEVECSVESEVSQKSLWNYDYAPP
PPPEQCLSDDEITMMAPVESKFSQSTGDIDKVTDTKPRVAEWRYGPARLWYDMLGVPEDG
SGFDYGFKLRKTEHEPVIKSRMIEEFRKLEENNGTDLLADENFLMVTQLHWEDDIIWDGE
DVKHKGTKPQRASLAGWLPSSMTRNAMAYNVQQGFAATLDDDKPWYSIFPIDNEDLVYGR
WEDNIIWDAQAMPRLLEPPVLTLDPNDENLILEIPDEKEEATSNSPSKESKKESSLKKSR
ILLGKTGVIKEEPQQNMSQPEVKDPWNLSNDEYYYPKQQGLRGTFGGNIIQHSIPAVELR
QPFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPLLKHIKKKAKMREQERQASGG
GEMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKY
GETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPETDFLIIRTRQGYYIRELVDI
FVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSE
SSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAMVSPEQCCAYYSMIAAEQRLK
DAGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFIAAMKGKCLLEVTGVADPTGC
GEGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKK
LSRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSS
TEVLSTDTDSSSAEDSDFEEMGKNIENMLQNKKTSSQLSREREEQERKELQRMLLAAGSA
ASGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEYVRCETVRKPAVIDAYVRIRT
TKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKKPKKMKERPD
LKLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQEEELEKTVIHNDNEELIKVE
GTKIVLGKQLIESADEVRRKSLVLKFPKQQLPPKKKRRVGTTVHCDYLNRPHKSIHRRRT
DPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLY
PSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLL
DDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISK
HKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDIC
TAKEAALEEAELESLDPMTPGPYTPQAKPPDLYDTNTSLSMSRDASVFQDESNMSVLDIP
SATPEKQVTQEGEDGDGDLADEEEGTVQQPQASVLYEDLLMSEGEDDEEDAGSDEEGDNP
FSAIQLSESGSDSDVGSGGIRPKQPRMLQENTRMDMENEESMMSYEGDGGEASHGLEDSN
ISYGSYEEPDPKSNTQDTSFSSIGGYEVSEEEEDEEEEEQRSGPSVLSQVHLSEDEEDSE
DFHSIAGDSDLDSDE
NT seq 5628 nt   +upstreamnt  +downstreamnt
atgtcagacacggacagcgacgaagattccgctggaggcggcccattttctttagcgggt
ttccttttcggcaacatcaatggagccgggcagctggagggggaaagcgtcttggatgat
gaatgtaagaagcacttggcaggcttgggggctttggggctgggcagcctgatcactgaa
ctcacggcaaatgaagaattgaccgggactgacggtgccttggtaaatgatgaagggtgg
gttaggagtacagaagatgctgtggactattcagacatcaatgaggtggcagaagatgaa
agccgaagataccagcagacgatggggagcttgcagcccctttgccactcagattatgat
gaagatgactatgatgctgattgtgaagacattgattgcaagttgatgcctcctccacct
ccacccccgggaccaatgaagaaggataaggaccaggattctattactggtgtgtctgaa
aatggagaaggcatcatcttgccctccatcattgccccttcctctttggcctcagagaaa
gtggacttcagtagttcctctgactcagaatctgagatgggacctcaggaagcaacacag
gcagaatctgaagatggaaagctgacccttccattggctgggattatgcagcatgatgcc
accaagctgttgccaagtgtcacagaactttttccagaatttcgacctggaaaggtgtta
cgttttctacgtctttttggaccagggaagaatgtcccatctgtttggcggagtgctcgg
agaaagaggaagaagaagcaccgtgagctgatacaggaagagcagatccaggaggtggag
tgctcagtagaatcagaagtcagccagaagtctttgtggaactacgactacgctccacca
ccacctccagagcagtgtctctctgatgatgaaatcacgatgatggctcctgtggagtcc
aaattttcccaatcaactggagatatagataaagtgacagataccaaaccaagagtggct
gagtggcgttatgggcctgcccgactgtggtatgatatgctgggtgtccctgaagatggc
agtgggtttgactatggcttcaaactgagaaagacagaacatgaacctgtgataaaatct
agaatgatagaggaatttaggaaacttgaggaaaacaatggcactgatcttctggctgat
gaaaacttcctgatggtgacacagctgcattgggaggatgatatcatctgggatggggag
gatgtcaaacacaaagggacaaaacctcagcgtgcaagcctggcaggctggcttccttct
agcatgactaggaatgcgatggcttacaatgttcagcaaggttttgcagccactcttgat
gatgacaaaccttggtactccatttttcccattgacaatgaggatctggtatatggacgc
tgggaggacaatatcatttgggatgctcaggccatgccccggctgttggaacctcctgtt
ttgacacttgatcccaatgatgagaacctcattttggaaattcctgatgagaaggaagag
gccacctctaactccccctccaaggagagtaagaaggaatcatctctgaagaagagtcga
attctcttagggaaaacaggagtcatcaaggaggaaccacagcagaacatgtctcagcca
gaagtgaaagatccatggaatctctccaatgatgagtattattatcccaagcaacagggt
cttcgaggcacctttggagggaatattatccagcattcaattcctgctgtggaattacgg
cagcccttctttcccacccacatggggcccatcaaactccggcagttccatcgcccacct
ctgaaaaagtactcatttggtgcactttctcagccaggtccccactcagtccaacctttg
ctaaagcacatcaaaaaaaaggccaagatgagagaacaagagaggcaagcttcaggtggt
ggagagatgttttttatgcgcacacctcaggacctcacaggcaaagatggtgatcttatt
cttgcagaatatagtgaggaaaatggacccttaatgatgcaggttggcatggcaaccaag
ataaagaactattataaacggaaacctggaaaagatcctggagcaccagattgtaaatat
ggggaaactgtttactgccatacatctcctttcctgggttctctccatcctggccaattg
ctgcaagcatttgagaacaacctttttcgtgctccaatttatcttcataagatgccagaa
actgatttcttgatcattcggacaagacagggttactatattcgggaattagtggatatt
tttgtggttggccagcagtgtcccttgtttgaagttcctgggcctaactccaaaagggcc
aatacgcatattcgagactttctacaggtttttatttaccgccttttctggaaaagtaaa
gatcggccacggaggatacgaatggaagatataaaaaaagcctttccttcccattcagaa
agcagcatccggaagaggctaaagctctgcgctgacttcaaacgcacagggatggactca
aactggtgggtgcttaagtctgattttcgtttaccaacggaagaagagatcagagctatg
gtgtcaccagagcagtgctgtgcttattatagcatgatagctgcagagcaacgactgaag
gatgctggctatggtgagaaatccttttttgctccagaagaagaaaatgaggaagatttc
cagatgaagattgatgatgaagttcgcactgccccttggaacaccacaagggccttcatt
gctgccatgaagggcaagtgtctgctagaggtgactggggtggcagatcccacggggtgt
ggtgaaggattctcctatgtgaagattccaaacaaaccaacacagcagaaggatgataaa
gaaccgcagccagtgaagaagacagtgacaggaacagatgcagaccttcgtcgcctttcc
ctgaaaaatgccaagcaacttctacgtaaatttggtgtgcctgaggaagagattaaaaag
ttgtcccgctgggaagtgattgatgtggtgcgcacaatgtcaacagaacaggctcgttct
ggagaggggcccatgagtaaatttgcccgtggatcaaggttttctgtggctgagcatcaa
gagcgttacaaagaggaatgtcagcgcatctttgacctacagaacaaggttctgtcatca
actgaagtcttatcaactgacacagacagcagctcagctgaagatagtgactttgaagaa
atgggaaagaacattgagaacatgttgcagaacaagaaaaccagctctcagctttcacgt
gaacgggaggaacaggagcggaaggaactacagcgaatgctactggcagcaggctcagca
gcatccggaaacaatcacagagatgatgacacagcttccgtgactagccttaactcttct
gccactggacgctgtctcaagatttatcgcacgtttcgagatgaagaggggaaagagtat
gttcgctgtgagacagtccgaaaaccagctgtcattgatgcctatgtgcgcatacggact
acaaaagatgaggaattcattcgaaaatttgccctttttgatgaacaacatcgggaagag
atgcgaaaagaacggcggaggattcaagagcaactgaggcggcttaagaggaaccaggaa
aaggagaagcttaagggtcctcctgagaagaagcccaagaaaatgaaggagcgtcctgac
ctaaaactgaaatgtggggcatgtggtgccattggacacatgaggactaacaaattctgc
cccctctattatcaaacaaatgcgccaccttccaaccctgttgccatgacagaagaacag
gaggaggagttggaaaagacagtcattcataatgataatgaagaacttatcaaggttgaa
gggaccaaaattgtcttggggaaacagctaattgagagtgcggatgaggttcgcagaaaa
tctctggttctcaagtttcctaaacagcagcttcctccaaagaagaaacggcgagttgga
accactgttcactgtgactatttgaatagacctcataagtccatccaccggcgccgcaca
gaccctatggtgacgctgtcgtccatcttggagtctatcatcaatgacatgagagatctt
ccaaatacataccctttccacactccagtcaatgcaaaggttgtaaaggactactacaaa
atcatcactcggccaatggacctacaaacactccgcgaaaacgtgcgtaaacgcctctac
ccatctcgggaagagttcagagagcatctggagctaattgtgaaaaatagtgcaacctac
aatgggccaaaacactcattgactcagatctctcaatccatgctggatctctgtgatgaa
aaactcaaagagaaagaagacaaattagctcgcttagagaaagctatcaaccccttgctg
gatgatgatgaccaagtggcgttttctttcattctggacaacattgtcacccagaaaatg
atggcagttccagattcttggccatttcatcacccagttaataagaaatttgttccagat
tattacaaagtgattgtcaatccaatggatttagagaccatacgtaagaacatctccaag
cacaagtatcagagtcgggagagctttctggatgatgtaaaccttattctggccaacagt
gttaagtataatggacctgagagtcagtatactaagactgcccaggagattgtgaacgtc
tgttaccagacattgactgagtatgatgaacatttgactcaacttgagaaggatatttgt
actgctaaagaagcagctttggaggaagcagaattagaaagcctggacccaatgacccca
gggccctacacgcctcaggctaagcctcctgatttgtatgataccaacacatccctcagt
atgtctcgagatgcctctgtatttcaagatgagagcaatatgtctgtcttggatattccc
agtgccactccagaaaagcaggtaacacaggaaggtgaagatggagatggtgatcttgca
gatgaagaggaaggaactgtacaacagcctcaagccagtgtcctgtatgaggatttgctt
atgtctgaaggagaagatgatgaggaagatgctgggagtgatgaagaaggagacaatcct
ttctctgctatccagctgagtgaaagtggaagtgactctgatgtgggatctggtggaata
agacccaaacaaccccgcatgcttcaggagaacacaaggatggacatggaaaatgaagaa
agcatgatgtcctatgagggagacggtggggaggcttcccatggtttggaggatagcaac
atcagttatgggagctatgaggagcctgatcccaagtcgaacacccaagacacaagcttc
agcagcatcggtgggtatgaggtatcagaggaggaagaagatgaggaggaggaagagcag
cgctctgggccgagcgtactaagccaggtccacctgtcagaggacgaggaggacagtgag
gatttccactccattgctggggacagtgacttggactctgatgaatga

  All links  
Disease (3)   
   OMIM (3)   
Gene (26)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (44)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (42)   
DNA sequence (96)   
   RefSeq(nuc) (52)   
   GenBank (22)   
   EMBL (22)   
3D Structure (64)   
   PDB (64)   
Protein domain (8)   
   Pfam (8)   
All databases (241)   

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