KEGG   Homo sapiens (human): 6908Help
Entry
6908              CDS       T01001                                 

Gene name
TBP, GTF2D, GTF2D1, HDL4, SCA17, TFIID
Definition
(RefSeq) TATA-box binding protein
  KO
K03120  transcription initiation factor TFIID TATA-box-binding protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa03022  Basal transcription factors
hsa05016  Huntington disease
hsa05165  Human papillomavirus infection
hsa05166  Human T-cell leukemia virus 1 infection
hsa05168  Herpes simplex infection
hsa05203  Viral carcinogenesis
Network
N00273  HCV NS5A to host-cell-protein inhibition
N00376  HPV E7 to TBP1-mediated transcription
Disease
H00063  Spinocerebellar ataxia (SCA)
H01243  Huntington disease-like syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03022 Basal transcription factors
    6908 (TBP)
 09160 Human Diseases
  09161 Cancers: Overview
   05203 Viral carcinogenesis
    6908 (TBP)
  09164 Neurodegenerative diseases
   05016 Huntington disease
    6908 (TBP)
  09172 Infectious diseases: Viral
   05166 Human T-cell leukemia virus 1 infection
    6908 (TBP)
   05168 Herpes simplex infection
    6908 (TBP)
   05165 Human papillomavirus infection
    6908 (TBP)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    6908 (TBP)
   03021 Transcription machinery [BR:hsa03021]
    6908 (TBP)
Transcription factors [BR:hsa03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   TATA-binding proteins
    6908 (TBP)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Basal transcription factors
    TFIID
     6908 (TBP)
  RNA polymerase III system
    TFIIIB
     6908 (TBP)
  RNA polymerase I system
    SL1/TIF-1B
     6908 (TBP)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: TBP EPL1 DDHD Presenilin DUF4746 MMR1 UPF0565 BORG_CEP SpoIIP ABC2_membrane_2 TFIIA Otopetrin Cellulose_synt BAF1_ABF1 PAT1 Tim54 EMC3_TMCO1 FemAB DUF3295 TraV DUF4228 DUF1501 Sin_N Ndc1_Nup
Motif
Other DBs
NCBI-GeneID: 6908
NCBI-ProteinID: NP_003185
OMIM: 600075
HGNC: 11588
Ensembl: ENSG00000112592
Vega: OTTHUMG00000016084
Pharos: P20226(Tbio)
UniProt: P20226 Q32MN7
Structure
PDB: 

Position
6q27
AA seq 339 aa AA seqDB search
MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQ
QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQ
LFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDL
KTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARV
VQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRI
VLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT
NT seq 1020 nt NT seq  +upstreamnt  +downstreamnt
atggatcagaacaacagcctgccaccttacgctcagggcttggcctcccctcagggtgcc
atgactcccggaatccctatctttagtccaatgatgccttatggcactggactgacccca
cagcctattcagaacaccaatagtctgtctattttggaagagcaacaaaggcagcagcag
caacaacaacagcagcagcagcagcagcagcagcaacagcaacagcagcagcagcagcag
cagcagcagcagcagcagcagcagcagcagcagcagcagcaacaggcagtggcagctgca
gccgttcagcagtcaacgtcccagcaggcaacacagggaacctcaggccaggcaccacag
ctcttccactcacagactctcacaactgcacccttgccgggcaccactccactgtatccc
tcccccatgactcccatgacccccatcactcctgccacgccagcttcggagagttctggg
attgtaccgcagctgcaaaatattgtatccacagtgaatcttggttgtaaacttgaccta
aagaccattgcacttcgtgcccgaaacgccgaatataatcccaagcggtttgctgcggta
atcatgaggataagagagccacgaaccacggcactgattttcagttctgggaaaatggtg
tgcacaggagccaagagtgaagaacagtccagactggcagcaagaaaatatgctagagtt
gtacagaagttgggttttccagctaagttcttggacttcaagattcagaatatggtgggg
agctgtgatgtgaagtttcctataaggttagaaggccttgtgctcacccaccaacaattt
agtagttatgagccagagttatttcctggtttaatctacagaatgatcaaacccagaatt
gttctccttatttttgtttctggaaaagttgtattaacaggtgctaaagtcagagcagaa
atttatgaagcatttgaaaacatctaccctattctaaagggattcaggaagacgacgtaa

DBGET integrated database retrieval system