KEGG   Homo sapiens (human): 6996
Entry
6996              CDS       T01001                                 
Symbol
TDG, hTDG
Name
(RefSeq) thymine DNA glycosylase
  KO
K20813  thymine-DNA glycosylase [EC:3.2.2.29]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03410  Base excision repair
Network
nt06504  Base excision repair
  Element
N01433  Base excision and strand cleavage by monofunctional glycosylase
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03410 Base excision repair
    6996 (TDG)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    6996 (TDG)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.2  Hydrolysing N-glycosyl compounds
    3.2.2.29  thymine-DNA glycosylase
     6996 (TDG)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA glycosylases
     6996 (TDG)
SSDB
Motif
Pfam: UDG Pox_Ag35
Other DBs
NCBI-GeneID: 6996
NCBI-ProteinID: NP_003202
OMIM: 601423
HGNC: 11700
Ensembl: ENSG00000139372
Pharos: Q13569(Tbio)
UniProt: Q13569 B4E127
Structure
Position
12:103965872..103988874
AA seq 410 aa
MEAENAGSYSLQQAQAFYTFPFQQLMAEAPNMAVVNEQQMPEEVPAPAPAQEPVQEAPKG
RKRKPRTTEPKQPVEPKKPVESKKSGKSAKSKEKQEKITDTFKVKRKVDRFNGVSEAELL
TKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLSEVQLNHMDDHT
LPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSK
EVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQLK
GIERNMDVQEVQYTFDLQLAQEDAKKMAVKEEKYDPGYEAAYGGAYGENPCSSEPCGFSS
NGLIESVELRGESAFSGIPNGQWMTQSFTDQIPSFSNHCGTQEQEEESHA
NT seq 1233 nt   +upstreamnt  +downstreamnt
atggaagcggagaacgcgggcagctattcccttcagcaagctcaagctttttatacgttt
ccatttcaacaactgatggctgaagctcctaatatggcagttgtgaatgaacagcaaatg
ccagaagaagttccagccccagctcctgctcaggaaccagtgcaagaggctccaaaagga
agaaaaagaaaacccagaacaacagaaccaaaacaaccagtggaacccaaaaaacctgtt
gagtcaaaaaaatctggcaagtctgcaaaatcaaaagaaaaacaagaaaaaattacagac
acatttaaagtaaaaagaaaagtagaccgttttaatggtgtttcagaagctgaacttctg
accaagactctccccgatattttgaccttcaatctggacattgtcattattggcataaac
ccgggactaatggctgcttacaaagggcatcattaccctggacctggaaaccatttttgg
aagtgtttgtttatgtcagggctcagtgaggtccagctgaaccatatggatgatcacact
ctaccagggaagtatggtattggatttaccaacatggtggaaaggaccacgcccggcagc
aaagatctctccagtaaagaatttcgtgaaggaggacgtattctagtacagaaattacag
aaatatcagccacgaatagcagtgtttaatggaaaatgtatttatgaaatttttagtaaa
gaagtttttggagtaaaggttaagaacttggaatttgggcttcagccccataagattcca
gacacagaaactctctgctatgttatgccatcatccagtgcaagatgtgctcagtttcct
cgagcccaagacaaagttcattactacataaaactgaaggacttaagagatcagttgaaa
ggcattgaacgaaatatggacgttcaagaggtgcaatatacatttgacctacagcttgcc
caagaggatgcaaagaagatggctgttaaggaagaaaaatatgatccaggttatgaggca
gcatatggtggtgcttacggagaaaatccatgcagcagtgaaccttgtggcttctcttca
aatgggctaattgagagcgtggagttaagaggagaatcagctttcagtggcattcctaat
gggcagtggatgacccagtcatttacagaccaaattccttcctttagtaatcactgtgga
acacaagaacaggaagaagaaagccatgcttaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (1)   
   KEGG NETWORK (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
   PHAROS (1)   
Protein sequence (9)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (47)   
   RefSeq(nuc) (7)   
   GenBank (20)   
   EMBL (20)   
3D Structure (21)   
   PDB (21)   
Protein domain (2)   
   Pfam (2)   
All databases (101)   

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