| Entry |
|
|---|
| Symbol |
TNFAIP3, A20, AISBL, OTUD7C, TNFA1P2
|
|---|
| Name |
(RefSeq) TNF alpha induced protein 3
|
|---|
| KO |
|
|---|
| Organism |
|
|---|
| Pathway |
| hsa04621 | NOD-like receptor signaling pathway |
|
|---|
| Network |
nt06121 TLR signaling (viruses and bacteria) nt06169 Measles virus (MV) |
|---|
| Element |
| N00692 | MV P to TLR2/4-NFKB signaling pathway |
|
|---|
| Disease |
| H02424 | Primary central nervous system lymphoma |
| H02434 | Diffuse large B-cell lymphoma, not otherwise specified |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
7128 (TNFAIP3)
04668 TNF signaling pathway
7128 (TNFAIP3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
7128 (TNFAIP3)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
7128 (TNFAIP3)
04657 IL-17 signaling pathway
7128 (TNFAIP3)
09160 Human Diseases
09172 Infectious disease: viral
05162 Measles
7128 (TNFAIP3)
05169 Epstein-Barr virus infection
7128 (TNFAIP3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:hsa01002]
7128 (TNFAIP3)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:hsa04121]
7128 (TNFAIP3)
Enzymes [BR:hsa01000]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.19 Omega peptidases
3.4.19.12 ubiquitinyl hydrolase 1
7128 (TNFAIP3)
Peptidases and inhibitors [BR:hsa01002]
Cysteine peptidases
Family C64
7128 (TNFAIP3)
Ubiquitin system [BR:hsa04121]
Deubiquitinating enzyme (DUB)
Ubiquitin-specific proteases (UBPs)
OTU
7128 (TNFAIP3)
|
|---|
| SSDB |
|
|---|
| Motif |
|
|---|
| Other DBs |
|
|---|
| Structure |
PDB: |
|---|
| Position |
6q23.3
|
|---|
| AA seq |
790 aa
MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQF
REIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDL
VLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTP
MARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPA
QECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKE
KLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENS
EQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPK
LNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRS
PGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCF
KRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGD
RTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGR
ECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARAS
CKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCN
ECFQFKQMYG |
|---|
| NT seq |
2373 nt +upstreamnt +downstreamnt
atggctgaacaagtccttcctcaggctttgtatttgagcaatatgcggaaagctgtgaag
atacgggagagaactccagaagacatttttaaacctactaatgggatcattcatcatttt
aaaaccatgcaccgatacacactggaaatgttcagaacttgccagttttgtcctcagttt
cgggagatcatccacaaagccctcatcgacagaaacatccaggccaccctggaaagccag
aagaaactcaactggtgtcgagaagtccggaagcttgtggcgctgaaaacgaacggtgac
ggcaattgcctcatgcatgccacttctcagtacatgtggggcgttcaggacacagacttg
gtactgaggaaggcgctgttcagcacgctcaaggaaacagacacacgcaactttaaattc
cgctggcaactggagtctctcaaatctcaggaatttgttgaaacggggctttgctatgat
actcggaactggaatgatgaatgggacaatcttatcaaaatggcttccacagacacaccc
atggcccgaagtggacttcagtacaactcactggaagaaatacacatatttgtcctttgc
aacatcctcagaaggccaatcattgtcatttcagacaaaatgctaagaagtttggaatca
ggttccaatttcgcccctttgaaagtgggtggaatttacttgcctctccactggcctgcc
caggaatgctacagataccccattgttctcggctatgacagccatcattttgtacccttg
gtgaccctgaaggacagtgggcctgaaatccgagctgttccacttgttaacagagaccgg
ggaagatttgaagacttaaaagttcactttttgacagatcctgaaaatgagatgaaggag
aagctcttaaaagagtacttaatggtgatagaaatccccgtccaaggctgggaccatggc
acaactcatctcatcaatgccgcaaagttggatgaagctaacttaccaaaagaaatcaat
ctggtagatgattactttgaacttgttcagcatgagtacaagaaatggcaggaaaacagc
gagcaggggaggagagaggggcacgcccagaatcccatggaaccttccgtgccccagctt
tctctcatggatgtaaaatgtgaaacgcccaactgccccttcttcatgtctgtgaacacc
cagcctttatgccatgagtgctcagagaggcggcaaaagaatcaaaacaaactcccaaag
ctgaactccaagccgggccctgaggggctccctggcatggcgctcggggcctctcgggga
gaagcctatgagcccttggcgtggaaccctgaggagtccactggggggcctcattcggcc
ccaccgacagcacccagcccttttctgttcagtgagaccactgccatgaagtgcaggagc
cccggctgccccttcacactgaatgtgcagcacaacggattttgtgaacgttgccacaac
gcccggcaacttcacgccagccacgccccagaccacacaaggcacttggatcccgggaag
tgccaagcctgcctccaggatgttaccaggacatttaatgggatctgcagtacttgcttc
aaaaggactacagcagaggcctcctccagcctcagcaccagcctccctccttcctgtcac
cagcgttccaagtcagatccctcgcggctcgtccggagcccctccccgcattcttgccac
agagctggaaacgacgcccctgctggctgcctgtctcaagctgcacggactcctggggac
aggacggggacgagcaagtgcagaaaagccggctgcgtgtattttgggactccagaaaac
aagggcttttgcacactgtgtttcatcgagtacagagaaaacaaacattttgctgctgcc
tcagggaaagtcagtcccacagcgtccaggttccagaacaccattccgtgcctggggagg
gaatgcggcacccttggaagcaccatgtttgaaggatactgccagaagtgtttcattgaa
gctcagaatcagagatttcatgaggccaaaaggacagaagagcaactgagatcgagccag
cgcagagatgtgcctcgaaccacacaaagcacctcaaggcccaagtgcgcccgggcctcc
tgcaagaacatcctggcctgccgcagcgaggagctctgcatggagtgtcagcatcccaac
cagaggatgggccctggggcccaccggggtgagcctgcccccgaagacccccccaagcag
cgttgccgggcccccgcctgtgatcattttggcaatgccaagtgcaacggctactgcaac
gaatgctttcagttcaagcagatgtatggctaa |
|---|
