KEGG   Homo sapiens (human): 7177
Entry
7177              CDS       T01001                                 

Gene name
TPSAB1, TPS1, TPS2, TPSB1, TPSB2, Tryptase-2
Definition
(RefSeq) tryptase alpha/beta 1
  KO
K01340  tryptase [EC:3.4.21.59]
Organism
hsa  Homo sapiens (human)
Pathway
hsa05164  Influenza A
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    7177 (TPSAB1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    7177 (TPSAB1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.59  tryptase
     7177 (TPSAB1)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S1: chymotrypsin family
   7177 (TPSAB1)
SSDB
Motif
Pfam: Trypsin Trypsin_2 DUF1986 DUF1929
Other DBs
NCBI-GeneID: 7177
NCBI-ProteinID: NP_003285
OMIM: 191080
HGNC: 12019
Ensembl: ENSG00000172236
Vega: OTTHUMG00000090467
Pharos: Q15661(Tclin) P20231(Tbio)
UniProt: Q15661 P20231
Structure
PDB: 

Position
16p13.3
AA seq 275 aa
MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCG
GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA
DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV
PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAG
VVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP
NT seq 828 nt   +upstreamnt  +downstreamnt
atgctgaatctgctgctgctggcgctgcccgtcctggcgagccgcgcctacgcggcccct
gccccaggccaggccctgcagcgagtgggcatcgtcgggggtcaggaggcccccaggagc
aagtggccctggcaggtgagcctgagagtccacggcccatactggatgcacttctgcggg
ggctccctcatccacccccagtgggtgctgaccgcagcgcactgcgtgggaccggacgtc
aaggatctggccgccctcagggtgcaactgcgggagcagcacctctactaccaggaccag
ctgctgccggtcagcaggatcatcgtgcacccacagttctacaccgcccagatcggagcg
gacatcgccctgctggagctggaggagccggtgaacgtctccagccacgtccacacggtc
accctgccccctgcctcagagaccttccccccggggatgccgtgctgggtcactggctgg
ggcgatgtggacaatgatgagcgcctcccaccgccatttcctctgaagcaggtgaaggtc
cccataatggaaaaccacatttgtgacgcaaaataccaccttggcgcctacacgggagac
gacgtccgcatcgtccgtgacgacatgctgtgtgccgggaacacccggagggactcatgc
cagggcgactccggagggcccctggtgtgcaaggtgaatggcacctggctgcaggcgggc
gtggtcagctggggcgagggctgtgcccagcccaaccggcctggcatctacacccgtgtc
acctactacttggactggatccaccactatgtccccaaaaagccgtga

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