KEGG   Homo sapiens (human): 7226
Entry
7226              CDS       T01001                                 
Symbol
TRPM2, EREG1, KNP3, LTRPC2, LTrpC-2, NUDT9H, NUDT9L1, TRPC7
Name
(RefSeq) transient receptor potential cation channel subfamily M member 2
  KO
K04977  transient receptor potential cation channel subfamily M member 2 [EC:3.6.1.13]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04621  NOD-like receptor signaling pathway
hsa04921  Oxytocin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    7226 (TRPM2)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    7226 (TRPM2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    7226 (TRPM2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.13  ADP-ribose diphosphatase
     7226 (TRPM2)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Transient receptor potential channel (TRP)
   7226 (TRPM2)
SSDB
Motif
Pfam: LSDAT_euk LSDAT_prok Ion_trans
Other DBs
NCBI-GeneID: 7226
NCBI-ProteinID: NP_003298
OMIM: 603749
HGNC: 12339
Ensembl: ENSG00000142185
UniProt: O94759
Structure
Position
21:44353621..44442644
AA seq 1503 aa
MEPSALRKAGSEQEEGFEGLPRRVTDLGMVSNLRRSNSSLFKSWRLQCPFGNNDKQESLS
SWIPENIKKKECVYFVESSKLSDAGKVVCQCGYTHEQHLEEATKPHTFQGTQWDPKKHVQ
EMPTDAFGDIVFTGLSQKVKKYVRVSQDTPSSVIYHLMTQHWGLDVPNLLISVTGGAKNF
NMKPRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRDFSLSSSYKEGELITIG
VATWGTVHRREGLIHPTGSFPAEYILDEDGQGNLTCLDSNHSHFILVDDGTHGQYGVEIP
LRTRLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIDNATTNGTPCVVVEGSGRVA
DVIAQVANLPVSDITISLIQQKLSVFFQEMFETFTESRIVEWTKKIQDIVRRRQLLTVFR
EGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFMDEWQWK
PSDLHPTMTAALISNKPEFVKLFLENGVQLKEFVTWDTLLYLYENLDPSCLFHSKLQKVL
VEDPERPACAPAAPRLQMHHVAQVLRELLGDFTQPLYPRPRHNDRLRLLLPVPHVKLNVQ
GVSLRSLYKRSSGHVTFTMDPIRDLLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILK
ELSKEEEDTDSSEEMLALAEEYEHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQL
ALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKRLQD
VGTPAARARAFFTAPVVVFHLNILSYFAFLCLFAYVLMVDFQPVPSWCECAIYLWLFSLV
CEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRLIPATLYPGRVILS
LDFILFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNE
RRVDWLFRGAVYHSYLTIFGQIPGYIDGVNFNPEHCSPNGTDPYKPKCPESDATQQRPAF
PEWLTVLLLCLYLLFTNILLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDLIEEYHGRPAA
PPPFILLSHLQLFIKRVVLKTPAKRHKQLKNKLEKNEEAALLSWEIYLKENYLQNRQFQQ
KQRPEQKIEDISNKVDAMVDLLDLDPLKRSGSMEQRLASLEEQVAQTAQALHWIVRTLRA
SGFSSEADVPTLASQKAAEEPDAEPGGRKKTEEPGDSYHVNARHLLYPNCPVTRFPVPNE
KVPWETEFLIYDPPFYTAERKDAAAMDPMGDTLEPLSTIQYNVVDGLRDRRSFHGPYTVQ
AGLPLNPMGRTGLRGRGSLSCFGPNHTLYPMVTRWRRNEDGAICRKSIKKMLEVLVVKLP
LSEHWALPGGSREPGEMLPRKLKRILRQEHWPSFENLLKCGMEVYKGYMDDPRNTDNAWI
ETVAVSVHFQDQNDVELNRLNSNLHACDSGASIRWQVVDRRIPLYANHKTLLQKAAAEFG
AHY
NT seq 4512 nt   +upstreamnt  +downstreamnt
atggagccctcagccctgaggaaagctggctcggagcaggaggagggctttgaggggctg
cccagaagggtcactgacctggggatggtctccaatctccggcgcagcaacagcagcctc
ttcaagagctggaggctacagtgccccttcggcaacaatgacaagcaagaaagcctcagt
tcgtggattcctgaaaacatcaagaagaaagaatgcgtgtattttgtggaaagttccaaa
ctgtctgatgctgggaaggtggtgtgtcagtgtggctacacgcatgagcagcacttggag
gaggctaccaagccccacaccttccagggcacacagtgggacccaaagaaacatgtccag
gagatgccaaccgatgcctttggcgacatcgtcttcacgggcctgagccagaaggtgaaa
aagtacgtccgagtctcccaggacacgccctccagcgtgatctaccacctcatgacccag
cactgggggctggacgtccccaatctcttgatctcggtgaccgggggggccaagaacttc
aacatgaagccgcggctgaagagcattttccgcagaggcctggtcaaggtggctcagacc
acaggggcctggatcatcacaggggggtcccacaccggcgtcatgaagcaggtaggcgag
gcggtgcgggacttcagcctgagcagcagctacaaggaaggcgagctcatcaccatcgga
gtcgccacctggggcactgtccaccgccgcgagggcctgatccatcccacgggcagcttc
cccgccgagtacatactggatgaggatggccaagggaacctgacctgcctagacagcaac
cactctcacttcatcctcgtggacgacgggacccacggccagtacggggtggagattcct
ctgaggaccaggctggagaagttcatatcggagcagaccaaggaaagaggaggtgtggcc
atcaagatccccatcgtgtgcgtggtgctggagggcggcccgggcacgttgcacaccatc
gacaacgccaccaccaacggcaccccctgtgtggttgtggagggctcgggccgcgtggcc
gacgtcattgcccaggtggccaacctgcctgtctcggacatcactatctccctgatccag
cagaaactgagcgtgttcttccaggagatgtttgagaccttcacggaaagcaggattgtc
gagtggaccaaaaagatccaagatatcgtccggaggcggcagctgctgactgtcttccgg
gaaggcaaggatggtcagcaggacgtggatgtggccatcttgcaggccttgctgaaagcc
tcacggagccaagaccactttggccacgagaactgggaccaccagctgaaactggcagtg
gcatggaatcgcgtggacattgcccgcagtgagatcttcatggatgagtggcagtggaag
ccttcagatctgcaccccacgatgacagctgcactcatctccaacaagcctgagtttgtg
aagctcttcctggagaacggggtgcagctgaaggagtttgtcacctgggacaccttgctc
tacctgtacgagaacctggacccctcctgcctgttccacagcaagctgcagaaggtgctg
gtggaggatcccgagcgcccggcttgcgcgcccgcggcgccccgcctgcagatgcaccac
gtggcccaggtgctgcgggagctgctgggggacttcacgcagccgctttatccccggccc
cggcacaacgaccggctgcggctcctgctgcccgttccccacgtcaagctcaacgtgcag
ggagtgagcctccggtccctctacaagcgttcctcaggccatgtgaccttcaccatggac
cccatccgtgaccttctcatttgggccattgtccagaaccgtcgggagctggcaggaatc
atctgggctcagagccaggactgcatcgcagcggccttggcctgcagcaagatcctgaag
gaactgtccaaggaggaggaggacacggacagctcggaggagatgctggcgctggcggag
gagtatgagcacagagccatcggggtcttcaccgagtgctaccggaaggacgaagagaga
gcccagaaactgctcacccgcgtgtccgaggcctgggggaagaccacctgcctgcagctc
gccctggaggccaaggacatgaagtttgtgtctcacgggggcatccaggccttcctgacc
aaggtgtggtggggccagctctccgtggacaatgggctgtggcgtgtgaccctgtgcatg
ctggccttcccgctgctcctcaccggcctcatctccttcagggagaagaggctgcaggat
gtgggcacccccgcggcccgcgcccgtgccttcttcaccgcacccgtggtggtcttccac
ctgaacatcctctcctacttcgccttcctctgcctgttcgcctacgtgctcatggtggac
ttccagcctgtgccctcctggtgcgagtgtgccatctacctctggctcttctccttggtg
tgcgaggagatgcggcagctcttctatgaccctgacgagtgcgggctgatgaagaaggca
gccttgtacttcagtgacttctggaataagctggacgtcggcgcaatcttgctcttcgtg
gcagggctgacctgcaggctcatcccggcgacgctgtaccccgggcgcgtcatcctctct
ctggacttcatcctgttctgcctccggctcatgcacatttttaccatcagtaagacgctg
gggcccaagatcatcattgtgaagcggatgatgaaggacgtcttcttcttcctcttcctg
ctggctgtgtgggtggtgtccttcggggtggccaagcaggccatcctcatccacaacgag
cgccgggtggactggctgttccgaggggccgtctaccactcctacctcaccatcttcggg
cagatcccgggctacatcgacggtgtgaacttcaacccggagcactgcagccccaatggc
accgacccctacaagcctaagtgccccgagagcgacgcgacgcagcagaggccggccttc
cctgagtggctgacggtcctcctactctgcctctacctgctcttcaccaacatcctgctg
ctcaacctcctcatcgccatgttcaactacaccttccagcaggtgcaggagcacacggac
cagatttggaagttccagcgccatgacctgatcgaggagtaccacggccgccccgccgcg
ccgccccccttcatcctcctcagccacctgcagctcttcatcaagagggtggtcctgaag
actccggccaagaggcacaagcagctcaagaacaagctggagaagaacgaggaggcggcc
ctgctatcctgggagatctacctgaaggagaactacctccagaaccgacagttccagcaa
aagcagcggcccgagcagaagatcgaggacatcagcaataaggttgacgccatggtggac
ctgctggacctggacccactgaagaggtcgggctccatggagcagaggttggcctccctg
gaggagcaggtggcccagacagcccaagccctgcactggatcgtgaggacgctgcgggcc
agcggcttcagctcggaggcggacgtccccactctggcctcccagaaggccgcggaggag
ccggatgctgagccgggaggcaggaagaagacggaggagccgggcgacagctaccacgtg
aatgcccggcacctcctctaccccaactgccctgtcacgcgcttccccgtgcccaacgag
aaggtgccctgggagacggagttcctgatctatgacccacccttttacacggcagagagg
aaggacgcggccgccatggaccccatgggagacaccctggagccactgtccacgatccag
tacaacgtggtggatggcctgagggaccgccggagcttccacgggccgtacacagtgcag
gccgggttgcccctgaaccccatgggccgcacaggactgcgtgggcgcgggagcctcagc
tgcttcggacccaaccacacgctgtaccccatggtcacgcggtggaggcggaacgaggat
ggagccatctgcaggaagagcataaagaagatgctggaagtgctggtggtgaagctccct
ctctccgagcactgggccctgcctgggggctcccgggagccaggggagatgctacctcgg
aagctgaagcggatcctccggcaggagcactggccgtcttttgaaaacttgctgaagtgc
ggcatggaggtgtacaaaggctacatggatgacccgaggaacacggacaatgcctggatc
gagacggtggccgtcagcgtccacttccaggaccagaatgacgtggagctgaacaggctg
aactctaacctgcacgcctgcgactcgggggcctccatccgatggcaggtggtggacagg
cgcatcccactctatgcgaaccacaagaccctcctccagaaggcagccgctgagttcggg
gctcactactga

  All links  
Disease (1)   
   OMIM (1)   
Gene (26)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (17)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (15)   
DNA sequence (47)   
   RefSeq(nuc) (17)   
   GenBank (15)   
   EMBL (15)   
3D Structure (15)   
   PDB (15)   
Protein domain (3)   
   Pfam (3)   
All databases (109)   

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