KEGG   Homo sapiens (human): 726
Entry
726               CDS       T01001                                 
Symbol
CAPN5, ADNIV, HTRA3, VRNI, nCL-3
Name
(RefSeq) calpain 5
  KO
K08574  calpain-5 [EC:3.4.22.-]
Organism
hsa  Homo sapiens (human)
Disease
H01798  Autosomal dominant neovascular inflammatory vitreoretinopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    726 (CAPN5)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.-
     726 (CAPN5)
Peptidases and inhibitors [BR:hsa01002]
 Cysteine peptidases
  Family C2: calpain family
   726 (CAPN5)
SSDB
Motif
Pfam: Peptidase_C2 Calpain_III C2
Other DBs
NCBI-GeneID: 726
NCBI-ProteinID: NP_004046
OMIM: 602537
HGNC: 1482
Ensembl: ENSG00000149260
UniProt: O15484 A0A140VKH4
Structure
Position
11:77066971..77126155
AA seq 640 aa
MFSCVKPYEDQNYSALRRDCRRRKVLFEDPLFPATDDSLYYKGTPGPAVRWKRPKGICED
PRLFVDGISSHDLHQGQVGNCWFVAACSSLASRESLWQKVIPDWKEQEWDPEKPNAYAGI
FHFHFWRFGEWVDVVIDDRLPTVNNQLIYCHSNSRNEFWCALVEKAYAKLAGCYQALDGG
NTADALVDFTGGVSEPIDLTEGDFANDETKRNQLFERMLKVHSRGGLISASIKAVTAADM
EARLACGLVKGHAYAVTDVRKVRLGHGLLAFFKSEKLDMIRLRNPWGEREWNGPWSDTSE
EWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFTDIIKCRVINTSHLSIHKTWEEARLH
GAWTLHEDPRQNRGGGCINHKDTFFQNPQYIFEVKKPEDEVLICIQQRPKRSTRREGKGE
NLAIGFDIYKVEENRQYRMHSLQHKAASSIYINSRSVFLRTDQPEGRYVIIPTTFEPGHT
GEFLLRVFTDVPSNCRELRLDEPPHTCWSSLCGYPQLVTQVHVLGAAGLKDSPTGANSYV
IIKCEGDKVRSAVQKGTSTPEYNVKGIFYRKKLSQPITVQVWNHRVLKDEFLGQVHLKAD
PDNLQALHTLHLRDRNSRQPSNLPGTVAVHILSSTSLMAV
NT seq 1923 nt   +upstreamnt  +downstreamnt
atgttctcgtgtgtgaagccctatgaggaccagaactactcagccctgaggcgggactgc
cggcgcaggaaggtgctcttcgaggaccccctcttccccgccactgacgactcactctac
tataagggcacgccggggcccgccgtcaggtggaagcgacccaagggcatctgcgaggac
ccccgcctctttgtggatggcatcagctcccacgacctgcaccagggccaggtgggcaac
tgctggtttgtggcagcctgctcgtcacttgcctcccgggagtcgctgtggcaaaaggtc
atcccagactggaaggagcaggaatgggaccccgaaaagcccaacgcctacgcgggcatc
ttccacttccacttctggcgcttcggggaatgggtggacgtggtcatcgatgaccggctg
cccacagtcaacaaccagctcatctactgccactccaactcccgcaatgagttttggtgc
gccctagtggagaaggcctatgccaaactggcaggctgttaccaggccctggatggaggc
aacacagcagacgcactggtggacttcacgggtggtgtttctgagcccatcgacctgacc
gagggtgactttgccaacgatgagactaagaggaaccagctctttgagcgcatgttaaag
gtgcacagccggggcggcctcatcagtgcctccatcaaggcagtgacagcagctgacatg
gaggcccgcctggcgtgcggcctggtaaagggccacgcatacgccgtcactgatgtgcgc
aaggtgcgcctgggccacggcctactggccttcttcaagtcagagaagttggacatgatc
cgcctgcgcaacccctggggcgagcgggagtggaacgggccctggagtgacacctcggag
gagtggcagaaagtgagcaagagtgagcgggagaagatgggtgtgaccgtgcaggacgac
ggtgagttctggatgaccttcgaggacgtgtgccggtacttcacggacatcatcaagtgc
cgcgtgatcaacacatcccacctgagcatccacaagacgtgggaggaggcccggctgcat
ggcgcctggacgctgcatgaggacccgcgacagaaccgcggtggcggctgcatcaaccac
aaggacaccttcttccagaacccacagtacatcttcgaagtcaagaagccagaagatgaa
gtcctgatctgcatccagcagcggccaaagcggtctacgcgccgggagggcaagggtgag
aacctggccattggctttgacatctacaaggtggaggagaaccgccagtaccgcatgcac
agcctgcagcacaaggccgccagctccatctacatcaactcacgcagcgtcttcctgcgc
accgaccagcccgagggccgctatgtcatcatccccacaaccttcgagccaggccacact
ggcgagttcctgctccgagtcttcactgatgtgccctccaactgccgggagctgcgcctg
gatgagcccccacacacctgctggagctccctctgtggctacccccagctggtgacccag
gtacatgtcctgggagctgctggcctcaaggactccccaacaggggctaactcttatgtg
atcatcaagtgtgagggagacaaagtccgctcggctgtgcagaagggcacctccacacca
gagtacaatgtgaaaggcatcttctaccgcaagaagctgagccagcccatcactgtacag
gtctggaaccaccgagtgctgaaggatgaatttctgggccaggtgcacctaaaggctgac
ccggacaacctccaggccctgcataccctccacctccgggaccgaaatagccggcagccc
agcaacctgccaggcactgtggccgtgcacattctcagcagcacctccctcatggctgtc
tga

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Ontology (3)   
   KEGG BRITE (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (29)   
   RefSeq(nuc) (5)   
   GenBank (12)   
   EMBL (12)   
3D Structure (1)   
   PDB (1)   
Protein domain (3)   
   Pfam (3)   
All databases (64)   

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