KEGG   Homo sapiens (human): 7267
Entry
7267              CDS       T01001                                 
Symbol
TTC3, DCRR1, RNF105, TPRDIII
Name
(RefSeq) tetratricopeptide repeat domain 3
  KO
K15712  E3 ubiquitin-protein ligase TTC3 [EC:2.3.2.27]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    7267 (TTC3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     7267 (TTC3)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    7267 (TTC3)
SSDB
Motif
Pfam: TTC3_DZIP3_dom zf-RING_2 TPR_1 TPR_2 zf-C3HC4_2 zf-C3HC4 zf-rbx1 TPR_16 zf-RING_5 TPR_12 TPR_11 zf-C3HC4_3 zf-RING_UBOX zf-RING_11 ANAPC3 TPR_17 TPR_9
Other DBs
NCBI-GeneID: 7267
NCBI-ProteinID: NP_001001894
OMIM: 602259
HGNC: 12393
Ensembl: ENSG00000182670
Pharos: P53804(Tbio)
UniProt: P53804
Position
21:37073254..37203118
AA seq 2025 aa
MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSER
NLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSRASEI
NLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKIENKILAMEEALNWIKYAGDVTI
LTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNE
EFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPK
GHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANK
DPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMANGGNQNLKVADEALKVD
DCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAH
QDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVY
GLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFE
KARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYS
KIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEG
VISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEA
KKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAM
LLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVE
PKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEKYGHKLDSIEGKQLDYF
SEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVK
NKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEF
EALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPE
ETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEY
VRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDN
SSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTY
LPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKN
AAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGN
SNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQ
VLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQ
QEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIE
EYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAY
PDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTV
HPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPE
ATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNS
TELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPV
TRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHK
GCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSSR
NT seq 6078 nt   +upstreamnt  +downstreamnt
atggacaattttgctgagggagatttcactgtggcggattatgccttgttagaagattgc
cctcacgtggatgattgtgtctttgctgctgaatttatgagcaatgattatgttcgtgtg
actcagctttactgtgatggggtgggtgtgcaatataaagattatatccaaagtgagagg
aatttggaatttgacatctgcagtatatggtgtagtaaaccaatttctgtcctgcaagat
tattgcgatgccattaaaataaacatcttctggccacttctgtttcaacatcaaaacagt
tccgtaatatcacgattgcatccctgtgtggacgccaacaattcacgtgcttctgagata
aatttgaagaaactacaacatcttgagttgatggaagatattgtggatttggcaaagaaa
gttgctaatgattcattccttattggaggcttattgagaattggttgtaaaatagaaaat
aaaatcttggcaatggaagaagctctgaattggataaaatatgcaggcgatgtaacaatt
ctaactaaattaggatcaattgacaattgttggcctatgttaagtattttctttactgaa
tacaagtaccacataactaaaattgtaatggaagactgcaatttgcttgaagaacttaaa
actcaaagttgtatggattgtatagaggaaggagaactaatgaaaatgaaaggaaatgaa
gagttttccaaagaaagatttgatatagctattatctattacaccagagccattgaatat
agacctgaaaactaccttctttatggtaaccgagctctttgttttcttcgtactggacag
tttagaaatgcactcggtgatggaaagagagccactattctgaagaacacttggccaaag
ggtcattatcgttattgtgatgctctttctatgctgggggaatatgactgggccctgcaa
gcaaacataaaagctcaaaaactctgtaaaaatgaccctgagggaatcaaggatctaatt
cagcagcatgtaaagttacaaaaacaaatagaagacctacaaggtcgaacagcaaataag
gatccaattaaagccttttatgaaaacagggcctacacacctaggagtttatcagcacct
atatttactacttcacttaactttgtggagaaggaaagagatttcagaaaaattaatcac
gaaatggccaacggtggtaatcagaatctaaaggtggcggatgaggcgttgaaggtagat
gattgtgactgtcatcctgaattttcaccaccatcaagtcagcctccaaaacataaagga
aaacaaaaatctcgaaacaatgaatcagaaaagttcagttctagttcaccattgacttta
ccagcagatttgaagaacatcttggagaaacagttttctaaatcttccagagctgcacac
caggattttgctaatataatgaaaatgctgagaagcttaattcaagatggctatatggcc
ttattggagcagcgttgccgcagcgctgcacaggcctttacagagttgctgaacggttta
gatcctcaaaaaataaagcaattgaacctggccatgattaactatgttttggtcgtctat
ggacttgccatttctctccttggaataggacagcctgaggaattatctgaagccgaaaac
cagtttaagaggattattgaacactaccccagtgagggccttgattgcttggcctactgt
ggaattggaaaagtatatttgaaaaaaaacagatttctagaagctctcaatcactttgag
aaagcaagaaccttgatttatcgtcttcctggagtgttaacttggcccacgagtaatgtg
attattgaagagtctcagccacaaaaaataaagatgctgttagagaaatttgttgaagaa
tgcaagttccctccagtgccagatgccatttgttgctatcagaagtgccatggatattct
aagatccagatatacataactgatccagactttaagggttttatacgcatcagctgttgc
cagtactgtaaaatagaatttcacatgaattgctggaagaagttaaaaactacaaccttt
aatgataaaattgacaaggattttctacaaggaatatgtcttacccctgactgtgaaggt
gtcatttctaagattatcatcttcagcagtggtggtgaagttaaatgtgaatttgaacac
aaggtcataaaagaaaaggttcctccaagacctattctgaaacagaaatgttctagccta
gagaaactaagactgaaagaagacaaaaaattgaagagaaagatccaaaaaaaagaagca
aaaaagttagcacaagaaagaatggaggaggacttaagagaaagtaatccacccaaaaat
gaagagcagaaagaaactgtagacaatgttcagcgttgtcagttccttgatgacagaatt
ctacagtgtataaagcagtatgctgacaagattaaatccggcatacagaatacagccatg
cttctcaaagaattgctttcttggaaagttttgagcacagaagactatacaacctgtttt
tctagcagaaattttctaaatgaagcagtggactatgttattcgccacttgattcaagaa
aataacagagtaaagacaagaatatttctgcatgttttgagtgagcttaaagaagtggag
cccaaattagccgcctggatccaaaaacttaatagctttggcttagatgccacaggaact
ttcttttctcgttatggagcatctcttaaactgcttgattttagtatcatgactttcctc
tggaatgagaaatatggtcacaaactagactctatagaaggaaagcaacttgattatttc
tctgagccagcatcattgaaggaagcccgttgtttaatatggctgctagaagaacacaga
gacaagttcccagcattgcatagtgctttagatgaattctttgatataatggacagccgc
tgtactgtgttaaggaaacaagatagtggtgaagcaccgtttagttcaaccaaggtgaaa
aacaaaagcaagaaaaagaagccaaaggattcaaagcctatgttagttgggtctggaaca
acttcagtaacttcaaataatgagatcatcacttcaagtgaagaccatagcaatcgaaat
tcagattctgcaggcccatttgcagtgcctgaccatcttcggcaagatgtagaagaattc
gaagctctctatgaccaacacagtaacgaatatgttgtccgcaataagaagctatgggac
atgaacccaaaacaaaaatgttcaactctatatgattacttctctcagtttttggaggaa
catggtcccttggacatgagtaacaagatgttctctgcagaatatgagtttttcccagaa
gaaactcgacagatactagaaaaagcaggaggtttaaaaccttttctcttgggatgccct
cgttttgttgtgattgacaactgtattgcactgaagaaggttgcatcacggctcaagaaa
aaaaggaagaagaaaaacattaaaacaaaagtagaagaaatttcaaaagcaggggagtat
gtacgagttaaactacaactgaatccagctgctagggaatttaaaccagatgtaaagtct
aaaccagtgtcagattcatcttcagcaccagcttttgaaaatgtgaaacccaaacctgtg
tctgcaaattctcccaagccagcttgtgaagatgtgaaggccaaaccagtatccgacaat
tcttctagacaagtttctgaggatgggcaacccaaaggggtctcttctaattctcctaaa
ccaggctctgaggatgcaaattacaagcgagtctcctgtaattcccccaaaccggttctt
gaggatgtgaaaccaacttattgggctcaatcccatttggtcacaggatactgtacgtat
cttcctttccagagatttgatatcacccagacaccgccagcatacataaacgtgttacca
ggtttgccccagtacaccagcatatatacacccttggccagcctttctcctgaatatcag
ctaccaagatcagtaccagtggtgccgtcttttgtagccaatgacagagcagataaaaat
gctgctgcctattttgagggtcatcatttgaatgctgagaatgttgctggtcaccagatt
gcctctgaaacacagatccttgagggctctttgggaatatctgtaaagtcacactgcagc
acaggtgatgctcatacagtcctgagtgagtctaacagaaatgatgagcactgtggaaat
tctaacaacaaatgtgaagtaattccagaaagcaccagtgcagtaacaaacattccacac
gtgcagatggttgccatacaggtatcttggaacataatacaccaagaagtcaatactgag
ccatataatccttttgaggaacgacaaggggaaatttcacggattgaaaaggagcaccaa
gtattacaagaccaacttcaagaagtgtatgaaaattatgagcagataaaacttaagggc
ttagaagagaccagggacctggaagagaagttgaaaaggcacttagaagaaaacaagatc
tcaaagacggaattagattggttccttcaagatttggaaagagaaattaaaaaatggcaa
caggaaaaaaaagaaatccaagaaagactaaaatcactgaagaagaaaattaaaaaggtt
tcaaatgccagtgaaatgtatacccagaaaaatgatggaaaggaaaaggaacatgaatta
catctggatcagtcccttgaaatcagcaacacacttacaaatgagaaaatgaaaatagaa
gagtatataaagaaagggaaagaggattatgaagagagtcatcagagagctgtggctgca
gaggtatccgtacttgaaaactggaaggagagtgaagtgtataagctacagatcatggag
tcacaagcagaagcctttctgaagaagctggggctgattagccgtgatcctgcagcatat
cctgacatggagtctgatatacgttcatgggaattgtttctttctaatgttacaaaagaa
attgagaaagcaaagtctcagtttgaagaacaaattaaggcaattaaaaatggttctcgg
ctcagtgaactttctaaagtgcagatttctgagctttcatttcctgcctgtaacacggtt
catcccgagttactccctgagtcttcaggcgacgatggccaagggcttgtgacttctgca
agcgacgtgactggaaaccacgcagcacttcacagggatcctagtgtgttctctgctggt
gattccccaggggaggctccttctgcgctgttgccagggccaccccctggtcagcctgaa
gccactcagctgacagggccaaaacgggctggccaggcagctctgtcagaacgaagccct
gtggctgatcggaagcagcctgttcctccaggacgtgctgcgcgttcaagccagtctcca
aaaaagccgttcaatagtattattgagcacctgtcagtggtattcccatgttacaacagc
actgagcttgctggttttattaaaaaagtgcgaagcaaaaacaagaactcactctcagga
ttgagtattgatgaaattgtccaaagagtgacagaacacattctagatgaacagaaaaag
aaaaagccaaacccaggaaaggacaagaggacttatgagcccagctctgccacccccgtg
accaggtcctcccagggctcaccctcggtggttgttgcaccatcacccaaaaccaagggg
cagaaagcagaagatgtccctgtgaggattgcactgggtgcaagttcctgtgaaatatgc
cacgaggtgttcaaatcaaaaaacgtgcgtgtgctcaaatgtgggcacaagtatcacaaa
gggtgctttaagcagtggcttaaagggcagagcgcttgcccggcctgccagggtcgtgat
ctcctgacagaagagtcaccttctggaagaggctggcccagtcagaatcaggagctgcct
tcctgctcttctaggtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (49)   
   KEGG ORTHOLOGY (1)   
   RefGene (39)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
Protein sequence (12)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (86)   
   RefSeq(nuc) (10)   
   GenBank (38)   
   EMBL (38)   
Protein domain (17)   
   Pfam (17)   
All databases (170)   

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