KEGG   Homo sapiens (human): 7294Help
Entry
7294              CDS       T01001                                 

Gene name
TXK, BTKL, PSCTK5, PTK4, RLK, TKL
Definition
(RefSeq) TXK tyrosine kinase
  KO
K08016  tyrosine-protein kinase TXK [EC:2.7.10.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04670  Leukocyte transendothelial migration
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    7294 (TXK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    7294 (TXK)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     7294 (TXK)
Protein kinases [BR:hsa01001]
 Non-receptor tyrosine kinases
  TEC family
   7294 (TXK)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase_Tyr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH3_10
Motif
Other DBs
NCBI-GeneID: 7294
NCBI-ProteinID: NP_003319
OMIM: 600058
HGNC: 12434
Ensembl: ENSG00000074966
Vega: OTTHUMG00000102065
Pharos: P42681(Tchem)
UniProt: P42681
Structure
PDB: 

Position
4p12
AA seq 527 aa AA seqDB search
MILSSYNTIQSVFCCCCCCSVQKRQMRTQISLSTDEELPEKYTQRRRPWLSQLSNKKQSN
TGRVQPSKRKPLPPLPPSEVAEEKIQVKALYDFLPREPCNLALRRAEEYLILEKYNPHWW
KARDRLGNEGLIPSNYVTENKITNLEIYEWYHRNITRNQAEHLLRQESKEGAFIVRDSRH
LGSYTISVFMGARRSTEAAIKHYQIKKNDSGQWYVAERHAFQSIPELIWYHQHNAAGLMT
RLRYPVGLMGSCLPATAGFSYEKWEIDPSELAFIKEIGSGQFGVVHLGEWRSHIQVAIKA
INEGSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENKG
KLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDDEY
VSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAIS
EGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAETW
NT seq 1584 nt NT seq  +upstreamnt  +downstreamnt
atgatcctttcctcctataacaccatccagtcggttttctgttgctgctgttgctgttca
gtgcagaagcgacaaatgagaacacagataagcctgagcacagatgaagagcttccagaa
aaatacacccagcgtcgcaggccgtggctcagccaattgtcaaataagaagcaatccaac
acgggccgtgtgcagccgtcaaaacgaaagccactgcctcccctcccaccctctgaggtt
gctgaagagaagatccaagtcaaggcactttatgattttctgcccagagaaccctgtaat
ttagccttaaggagagcagaagaatacctgatactggagaaatacaatcctcactggtgg
aaggcaagagaccgtttggggaatgaaggcttaatcccaagcaactatgtgactgaaaac
aaaataactaatttagaaatatatgagtggtaccatagaaacattaccagaaatcaggca
gaacatctattgagacaagagtctaaagaaggtgcatttattgtcagagattcaagacat
ttaggatcctacacaatttccgtatttatgggagctagaagaagtacggaggctgccata
aaacattatcagataaaaaagaatgactcaggacagtggtatgtggctgaaagacacgcc
tttcaatcaatccctgagttaatctggtatcaccagcacaatgcagccggtctcatgact
cgtctccgatatccagttgggctgatgggcagttgtttaccagccacagctgggtttagc
tacgaaaagtgggagatagatccatctgagttggcttttataaaggagattggaagcggt
cagtttggagtggtccatttaggtgaatggcggtcacatatccaggtagctatcaaggcc
atcaatgaaggctccatgtctgaagaggatttcattgaagaggccaaagtgatgatgaaa
ttatctcattcaaagctagtgcaactttatggagtctgtatacagcggaagcccctttac
attgtgacagagttcatggaaaatggctgcctgcttaactatctcagggagaataaagga
aagcttaggaaggaaatgctactgagtgtatgccaggatatatgtgaaggaatggaatat
ctggagaggaatggctatattcatagggatttggcggcaaggaattgtttggtcagttca
acatgcatagtaaaaatttcagactttggaatgacaaggtacgttttggatgatgagtat
gtcagttcttttggagccaagttcccaatcaagtggtcccctcctgaagtttttcttttc
aataagtacagcagtaaatctgatgtctggtcatttggagttttaatgtgggaagttttt
acagaaggaaaaatgccttttgaaaataagtcaaatttgcaagtcgtggaagctatttct
gaaggcttcaggctatatcgccctcacctggcaccaatgtccatatatgaagtcatgtac
agctgctggcatgagaaacctgaaggccgccctacatttgccgagctgctgcgggctgtc
acagagattgcggaaacctggtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (17)   
   RefSeq(nuc) (7)   
   GenBank (5)   
   EMBL (5)   
Protein domain (7)   
   Pfam (7)   
All databases (64)   

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