KEGG   Homo sapiens (human): 729438Help
Entry
729438            CDS       T01001                                 

Gene name
CASTOR2, GATSL1, GATSL2
Definition
(RefSeq) cytosolic arginine sensor for mTORC1 subunit 2
  KO
K23081  cytosolic arginine sensor for mTORC1 subunit 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04150  mTOR signaling pathway
Drug target
Sapanisertib: D11183
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    729438 (CASTOR2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: ACT_7 Castor1_N
Motif
Other DBs
NCBI-GeneID: 729438
NCBI-ProteinID: NP_001138536
OMIM: 617033
HGNC: 37073
Ensembl: ENSG00000274070
Vega: OTTHUMG00000181541
Pharos: A6NHX0(Tdark)
UniProt: A6NHX0
Position
7q11.23
AA seq 329 aa AA seqDB search
MELHILEHRLQVASVAKESIPLFTYGLIKLAFLSSKTRCKFFSLTETPEDYTIIVDEEGF
LELPSSEHLSVADATWLALNVVSGGGSFSSSQPIGVTKIAKSVIAPLADQNISVFMLSTY
QTDFILVRERDLPFVTHTLSSEFTILRVVNGETVAAENLGITNGFVKPKLVQRPVIHPLS
SPSNRFCVTSLDPDTLPAVATLLMDVMFYSNGVKDPMATGDDCGHIRFFSFSLIEGYISL
VMDVQTQQRFPSNLLFTSASGELWKMVRIGGQPLGFDECGIVAQISEPLAAADIPAYYIS
TFKFDHALVPEENINGVISALKVSQAEKH
NT seq 990 nt NT seq  +upstreamnt  +downstreamnt
atggaactccacatcctggagcaccggctgcaagttgccagcgtcgccaaggagagtatc
ccgctgttcacctacggcctgatcaaacttgccttcctgtcctccaagaccaggtgcaag
ttcttcagtctgactgagacgccagaggattacactatcattgtcgatgaggaaggattc
ctagagctgccctcctcggagcacctgagtgtggcagatgccacctggctggccctgaac
gtggtgtccggcggtggcagcttctccagctcccagcccatcggcgtgaccaagatcgcc
aagtcagtcatcgccccactggctgaccagaacatatccgtgttcatgctgtccacgtat
cagacagacttcatcctggtgcgcgagcgggacctgccctttgtcacccacacattgtca
tcagagttcaccatcctgcgggtcgtcaatggcgagaccgtggcagccgagaacctcggc
atcaccaatggcttcgtgaagcccaagctggtccagaggccagtcatccacccactgtcc
agcccgagcaacaggttctgtgtcaccagcctggaccctgacacgctgcctgctgttgcc
acactcctcatggatgtcatgttctactccaatggagtgaaggaccccatggccactggg
gatgactgcggccacatccgcttcttctccttctccctcatcgagggctacatctccctg
gtgatggacgtgcagacgcagcagaggtttcctagtaacttgctgttcacaagcgcatcc
ggagagctctggaagatggtccggattggaggacagcccctggggtttgatgagtgtggc
atcgtggcccagatctcagagcccttggctgctgcagacatcccagcctactacatcagt
actttcaagtttgatcatgcacttgtccccgaagagaacatcaatggtgtcatcagtgcc
ctgaaggtcagccaagcagagaagcactag

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (24)   
   RefSeq(nuc) (2)   
   GenBank (11)   
   EMBL (11)   
Protein domain (2)   
   Pfam (2)   
All databases (44)   

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