KEGG   Homo sapiens (human): 7306
Entry
7306              CDS       T01001                                 
Symbol
TYRP1, CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRP, b-PROTEIN
Name
(RefSeq) tyrosinase related protein 1
  KO
K00506  tyrosinase-related protein 1 [EC:1.14.18.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00350  Tyrosine metabolism
hsa01100  Metabolic pathways
hsa04916  Melanogenesis
Network
nt06028  Dopamine and serotonin metabolism
  Element
N01552  Eumelanin biosynthesis
Disease
H00168  Oculocutaneous albinism
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    7306 (TYRP1)
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    7306 (TYRP1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    7306 (TYRP1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of melanoma cells
   7306 (TYRP1)
SSDB
Motif
Pfam: Tyrosinase EGF_laminin CD34_antigen EGF_Teneurin
Other DBs
NCBI-GeneID: 7306
NCBI-ProteinID: NP_000541
OMIM: 115501
HGNC: 12450
Ensembl: ENSG00000107165
UniProt: P17643
Structure
Position
9:12693385..12710285
AA seq 537 aa
MSAPKLLSLGCIFFPLLLFQQARAQFPRQCATVEALRSGMCCPDLSPVSGPGTDRCGSSS
GRGRCEAVTADSRPHSPQYPHDGRDDREVWPLRFFNRTCHCNGNFSGHNCGTCRPGWRGA
ACDQRVLIVRRNLLDLSKEEKNHFVRALDMAKRTTHPLFVIATRRSEEILGPDGNTPQFE
NISIYNYFVWTHYYSVKKTFLGVGQESFGEVDFSHEGPAFLTWHRYHLLRLEKDMQEMLQ
EPSFSLPYWNFATGKNVCDICTDDLMGSRSNFDSTLISPNSVFSQWRVVCDSLEDYDTLG
TLCNSTEDGPIRRNPAGNVARPMVQRLPEPQDVAQCLEVGLFDTPPFYSNSTNSFRNTVE
GYSDPTGKYDPAVRSLHNLAHLFLNGTGGQTHLSPNDPIFVLLHTFTDAVFDEWLRRYNA
DISTFPLENAPIGHNRQYNMVPFWPPVTNTEMFVTAPDNLGYTYEIQWPSREFSVPEIIA
IAVVGALLLVALIFGTASYLIRARRSMDEANQPLLTDQYQCYAEEYEKLQNPNQSVV
NT seq 1614 nt   +upstreamnt  +downstreamnt
atgagtgctcctaaactcctctctctgggctgtatcttcttccccttgctactttttcag
caggcccgggctcaattcccaagacagtgtgccactgttgaggctttgagaagtggtatg
tgttgcccagacctgtcccctgtgtctgggcctgggacagaccgctgtggctcatcatca
gggaggggcagatgtgaggcagtgactgcagactcccggccccacagccctcagtatccc
catgatggcagagatgatcgggaggtctggcccttgcgcttcttcaataggacatgtcac
tgcaacggcaatttctcaggacacaactgtgggacgtgccgtcctggctggagaggagct
gcctgtgaccagagggttctcatagtcaggagaaatcttctggacttaagtaaagaagaa
aagaaccactttgtccgggccctggatatggcaaagcgcacaactcaccctttatttgtc
attgccaccaggagatcagaagaaatactggggccagatggcaacacgccacaatttgag
aacatttccatttataactactttgtttggacacactattactcagtcaaaaagactttc
cttggggtaggacaggaaagctttggtgaagtggatttctctcatgagggaccagctttt
ctcacatggcacaggtaccacctcctgcgtctggagaaagacatgcaggaaatgttgcaa
gagccttctttctcccttccttactggaattttgcaacggggaaaaatgtctgtgatatc
tgcacggatgacttgatgggatccagaagcaactttgattccactctaataagcccaaac
tctgtcttttctcaatggcgagtggtctgtgactccttggaagattatgataccctggga
acactttgtaacagcaccgaggatgggccaattaggagaaatccagctggaaatgtggcc
agaccaatggtgcaacgtcttcctgaaccacaggatgtcgctcagtgcttggaagttggt
ttatttgacacgcctcctttttattccaactctacaaacagtttccgaaacacagtggaa
ggttacagtgaccccacgggaaagtatgaccctgctgttcgaagtcttcacaatttggct
catctattcctgaatggaacagggggacaaacccatttgtctccaaatgatcctattttt
gtcctcctgcacaccttcacagatgcagtctttgatgaatggctgaggagatacaatgct
gatatatccacatttccattggaaaatgcccctattggacataatagacaatacaacatg
gtgccattctggcccccagtcaccaacacagaaatgtttgttactgctccagacaacctg
ggatacacttatgaaattcaatggccaagtcgggagtttagtgtacctgagataattgcc
atagcagtagttggcgctttgttactggttgcactcatttttgggactgcttcttatctg
attcgtgccagacgcagtatggatgaagctaaccagcctctcctcactgatcagtatcaa
tgctatgctgaagaatatgaaaaactccagaatcctaatcagtctgtggtctaa

  All links  
Disease (3)   
   OMIM (3)   
Gene (17)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (19)   
   RefSeq(nuc) (3)   
   GenBank (8)   
   EMBL (8)   
3D Structure (13)   
   PDB (13)   
Protein domain (4)   
   Pfam (4)   
All databases (61)   

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